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Noonan Syndrome in Thai Children

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Abstract

This study describes clinical features of Noonan syndrome and gene mutations, including PTPN11, SOS1, and BRAF in the Thai population. Widely spaced eyes were the most common finding from the digital facial analysis technology used in this study.

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Acknowledgments

Antonio R. Porras and Professor Marius George Linguraru, Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National Hospital, Washington DC for facial profile data analysis. Dr. Paul Kruszka, Medical Genetics Branch, National Human Genome Research Institute, NIH, for genetic testing.

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Authors and Affiliations

  1. Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

    Nonglak Boonchooduang & Orawan Louthrenoo

  2. Division of Genetics and Metabolism, Children National Health System, Washington, District of Columbia, USA

    Pranoot Tanpaiboon

Authors
  1. Nonglak Boonchooduang
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  2. Orawan Louthrenoo
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  3. Pranoot Tanpaiboon
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Contributions

All authors contributed to the study design, data interpretation, drafting the article/critical review and final approval of the manuscript.

Corresponding author

Correspondence to Nonglak Boonchooduang.

Ethics declarations

Ethics Research Committee of the Faculty of Medicine, Chiang Mai University; No. PED-2559-04024 dated 9 September, 2016.

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Competing interest

None stated.

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Boonchooduang, N., Louthrenoo, O. & Tanpaiboon, P. Noonan Syndrome in Thai Children. Indian Pediatr 57, 967–968 (2020). https://doi.org/10.1007/s13312-020-2007-3

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  • DOI: https://doi.org/10.1007/s13312-020-2007-3

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