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2019 Update on Primary Immunodeficiency Disorders by the International Union of Immunological Societies

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Abstract

International Union of Immunological Societies working group recently updated the human inborn errors of immunity. This classification includes 65 new disorders that have been added since the last classification in 2018. This article highlights the important aspects of new classification for the benefit of general pediatricians.

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References

  1. Tangye SG, Al-Herz W, Bousfiha A, Chatila T, Cunningham-Rundles C, Etzioni A, et al. Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee. J Clin Immunol. 2020

  2. Picard C, Bobby Gaspar H, Al-Herz W, Bousfiha A, Casanova J-L, Chatila T, et al. International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity. J Clin Immunol. 2018;38(1):96–128.

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  3. Bousfiha A, Jeddane L, Picard C, Al-Herz W, Ailal F, Chatila T, et al. Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. J Clin Immunol. 2020: 11; 1–16.

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Funding

Indian Council of Medical Research (ICMR)

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BU: conceived and written the manuscript. MM revised the manuscript for important intellectual content. The final manuscript was approved by all authors.

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Correspondence to Manisha Rajan Madkaikar.

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Bargir, U.A., Madkaikar, M.R. 2019 Update on Primary Immunodeficiency Disorders by the International Union of Immunological Societies. Indian Pediatr 57, 565–567 (2020). https://doi.org/10.1007/s13312-020-1856-0

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  • DOI: https://doi.org/10.1007/s13312-020-1856-0

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