Abstract
Objective
To assess outcomes and factors influencing outcomes in neonates requiring cardiac surgery in India.
Methods
This study reports on review of hospital data from a tertiary care cardiac surgical institute from January-2009 to December-2015.
Results
A total of 200 neonates were included; of them, 5% of the cases were antenatally diagnosed and most of them had unmonitored transport (111, 55.5%). The overall mortality rate was 13.5%, (n=27) and 178 (89%) underwent complete defect repair. There was a significant association of mortality with shock, the number of inotropes, intra-operative procedure, residual lesion, aortic cross-clamp and deep hypothermic circulatory arrest time (all P<0.05). Logistic regression analysis showed ventilation duration, cardiac-bypass time, shock, and residual cardiac lesion as independent predictors of mortality.
Conclusion
Cardiac defects were found to have late detection and most transports were unmonitored. Complete surgical repair and shorter cardiac bypass time can potentially improve neonatal cardiac surgical outcomes.
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VS: conceptualized and planned the study, drafted the proposal and manuscript, planned and conducted data collection, revised the manuscript; PB: planned the study design, conducted data collection, analyzed the data, and modified the manuscript for important intellectual points; SM,SR: planned the study design, modified the manuscript for important intellectual points; PJ: planned the study design, oversaw data collection, modified the manuscript for important intellectual points; VJ: conceptualized and devised the study, oversaw data collection, supervised the progress of the study, analyzed the data, provided important intellectual inputs to the manuscript. He will be the guarantor for the study. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.
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Shukla, V.V., Bobhate, P., Mohanty, S. et al. Early Outcomes of Neonatal Cardiac Surgery in India. Indian Pediatr 57, 129–132 (2020). https://doi.org/10.1007/s13312-020-1729-6
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DOI: https://doi.org/10.1007/s13312-020-1729-6