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Nebulized N-Acetylcysteine for Management of Plastic Bronchitis

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Abstract

Background

Plastic bronchitis is characterized by formation of extensive obstructive endobronchial casts and high recurrence rates.

Case characteristics

Two children (1-year-old girl, 7-year-old boy) who had recurrent episodes of respiratory distress with acute worsening. Bronchoscopy revealed membrane-like casts. Both children were managed with nebulized N-acetylcysteine in addition to management for asthma.

Outcome

Symptom-free without recurrence for more than 9 months of follow-up.

Message

Nebulized N-acetylcysteine may be helpful in prevention of recurrence of plastic bronchitis due to asthma.

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References

  1. Seear M, Hui H, Magee F, Bohn D, Cutz E. Bronchial casts in children: A proposed classification based on nine cases and a review of the literature. Am J Respir Crit Care Med. 1997;155:364–70.

    Article  PubMed  CAS  Google Scholar 

  2. Eberlein MH, Drummond MB, Haponik EF. Plastic bronchitis: A management challenge. Am J Med Sci. 2008;335:163–9.

    Article  PubMed  Google Scholar 

  3. Berlucchi M, Pelucchi F, Timpano S, Zorzi A, Padoan R. A conservative treatment for plastic bronchitis in pediatric age. Am J Otolaryngol. 2014;35:204–6.

    Article  PubMed  Google Scholar 

  4. Kim E, Park J, Kim D, Lee J. Plastic bronchitis in an adult with asthma. Tuber Respir Dis. 2012;73:122–6.

    Article  Google Scholar 

  5. Colaneri M, Quarti A, Pozzi M, Gasparini S, Carloni I, de Benedictis F. Management of plastic bronchitis with nebulized tissue plasminogen activator: another brick in the wall. Italian J Pediatr. 2014;40:1–8.

    Article  CAS  Google Scholar 

  6. Kunder R, Kunder C, Mark J, Berry G, Roth S, Frankovich J, et al. Pediatric plastic bronchitis: case report and retrospective comparative analysis of epidemiology and pathology. Case Rep Pulmonol. 2013;2013:649365.

    PubMed  PubMed Central  Google Scholar 

  7. Turgut T, Ýn E, Özercan Ý, Kaplanmd M. A case of plastic bronchitis. Arch Iranian Med. 2014;17:589–90.

    Google Scholar 

  8. Hasan R, Black C, Reddy R. Plastic bronchitis in children. Fetal Pediatr Pathol. 2012;31:87–93.

    Article  PubMed  Google Scholar 

  9. Dori Y, Keller M, Rychik J, Itkin M. Successful treatment of plastic bronchitis by selective lymphatic embolization in a Fontan patient. Pediatrics. 2014;134:e590–5.

    Article  Google Scholar 

  10. Mateos–Corral D, Cutz E, Solomon M, Ratjen F. Plastic bronchitis as an unusual cause of mucus plugging in cystic fibrosis. Pediatr Pulmonol. 2009;44:939–40.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India

    Animesh Kumar, Kana Ram Jat & Rakesh Lodha

  2. Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India

    M. Srinivas

Authors
  1. Animesh Kumar
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  2. Kana Ram Jat
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  3. M. Srinivas
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  4. Rakesh Lodha
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Corresponding author

Correspondence to Rakesh Lodha.

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Kumar, A., Jat, K.R., Srinivas, M. et al. Nebulized N-Acetylcysteine for Management of Plastic Bronchitis. Indian Pediatr 55, 701–703 (2018). https://doi.org/10.1007/s13312-018-1363-8

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  • DOI: https://doi.org/10.1007/s13312-018-1363-8

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