Skip to main content
Log in

Joint involvement in children with celiac disease

  • Research Paper
  • Published:
Indian Pediatrics Aims and scope Submit manuscript

Abstract

Objective

To determine early joint involvement as detected by ultrasonography in children with newly diagnosed celiac disease, and in children with celiac disease on gluten-free diet for more than 6 months.

Methods

Cross-sectional comparative study evaluating joint abnormalities by ultrasonography.

Results

Ultrasonography showed abnormalities in 19 out of 60 (31.7%) children with newly diagnosed celiac disease as compared to 2 (3.3%) out of 60 in those on a gluten-free diet for more than 6 months.

Conclusion

Subclinical synovitis as detected by ultrasound is a frequent finding in newly diagnosed children with celiac disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Garg K, Gupta RK. What a practitioner needs to know about celiac disease? Indian J Pediatr. 2015;82:145–51.

    Article  PubMed  Google Scholar 

  2. Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, et al. European Society for Paediatric Gastroenterology, Hepatology, and Nutrition Guidelines for the diagnosis of celiac disease. J Pediatr Gastroenterol Nutr. 2012;54:136–60.

    Article  CAS  PubMed  Google Scholar 

  3. Demir H, Yüce A, Koçak N, Özen H, Gürakan F. Celiac disease in Turkish children: Presentation of 104 cases. Pediatr Int. 2000;42:483–7.

    Article  CAS  PubMed  Google Scholar 

  4. Celiloðlu C, Karabiber H, Selimoðlu MA. Atypical presentations of celiac disease. Turkish J Pediatr. 2011;53:241–9.

    Google Scholar 

  5. Bourne JT, Kumar P, Huskisson EC, Mageed R, Unsworth DJ, Wojtulewskija. Arthritis and coeliac disease. Ann Rheum Dis. 1985;44:592–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Dawidowicz K, EA HK, Lahalle S, Qubaja M, Liote F. Unexplained polyarthralgia and celiac disease. Joint Bone Spine. 2008;75:325–8.

    Article  PubMed  Google Scholar 

  7. Hadjivassiliou M, Chattopadhyay AK, Grunewald RA, Jarratt JA, Kandler RH, Rao DG, et al. Myopathy associated with gluten sensitivity. Muscle Nerve. 2007;35:443–50.

    Article  CAS  PubMed  Google Scholar 

  8. Iagnocco A, Ceccareli F, Perricone C, Valesini G. The role of ultrasound in rheumatology. Semin Ultrasound CT MR. 2011;32:66–73. 29-350.

    Article  PubMed  Google Scholar 

  9. Tok F, Demirkaya E, Ozcakar L. Musculoskeletal ultrasound in pediatric rheumatology. Pediatric Rheumatol WHAT THIS STUDY ADDS? • Subclinical synovitis, most commonly in knee joint, as detected by ultrasonography may be present in about one-third of newly diagnosed children with celiac disease. Online J. 2011;9:25.

    Google Scholar 

  10. Porta F, Radunovic G, Vlad V, Micu MC, Nestorova R, Petranova T, et al. The role of Doppler ultrasound in rheumatic diseases. Rheumatology (Oxford). 2012;51:976–82.

    Article  PubMed  Google Scholar 

  11. Ramos PC, Ceccarelli F, Jousse-Joulin S. Role of ultrasound in the assessment of juvenile idiopathic arthritis. Rheumatology (Oxford). 2012;51:vii10-2. 16

    Article  Google Scholar 

  12. Adelizzi RA, Pecora AA, Chiesa JC. Celiac disease: Case report with an associated arthropathy. Am J Gastroenterol. 1982;77:481–5.

    CAS  PubMed  Google Scholar 

  13. Chakravarty K, Scott DG. Oligoarthritis-A presenting feature of occult coeliac disease. Br J Rheumatol. 1992;31:349–50.

    Article  CAS  PubMed  Google Scholar 

  14. Borg AA, Dawes CH, Swan CH, Hothersall TE. Persistent monoarthritis and occult coeliac disease. P ostgrad Med J. 1994;70:51–63.

    CAS  Google Scholar 

  15. Lubrano E, Ciacci C, Ames PR, Mazzacca G, Oriente P, Scarpa R. The arthritis of coeliac disease: Prevalence and pattern in 200 adult patients. Br J Rheumatol. 1996;35:1314–8.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kapil Garg.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Garg, K., Agarwal, P., Gupta, R.K. et al. Joint involvement in children with celiac disease. Indian Pediatr 54, 946–948 (2017). https://doi.org/10.1007/s13312-017-1188-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-017-1188-x

Keywords

Navigation