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Maternal pseudo-Bartter syndrome associated with severe perinatal brain injury

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Abstract

Background

Maternal electrolyte imbalance is rarely reported as causative factor of severe perinatal brain injury.

Case characteristics

This case outlines a unique maternal and neonatal pseudo-Bartter syndrome presented with metabolic alkalosis and hypochloremia due to maternal severe vomiting.

Observation

Neonatal MRI brain revealed extensive brain hemorrhages with porencephalic cysts. Subsequent investigation workup points towards maternal severe metabolic alkalosis as its cause.

Message

Careful medical attention should be paid to pregnant women with excessive vomiting to ensure a healthy outcome for both the mother and the baby.

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References

  1. Calisici E, Eras Z, Oncel MY, Oguz SS, Gokce ÝK, Dilmen U. Neurodevelopmental outcomes of premature infants with severe intraventricular hemorrhage. J Matern Fetal Neonatal Med. 2015;28:2115–20.

    Article  PubMed  Google Scholar 

  2. Lee NM, Saha S. Nausea and vomiting of pregnancy. Gastroenterol Clin North Am. 2011;40:309.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Mathot M, Maton P, Henrion E, Francosis-Adant A, Murguglio A, Gaillez S, et al. Pseudo-Bartter syndrome in a pregnant mother and her fetus. Pediatr Nephrol. 2006;21:1037–40.

    Article  PubMed  Google Scholar 

  4. Nakagawa A, Furuhashi M, Kidokoro K, Yoshida K, Kuno N, Ishikawa K. Maternal excessive vomiting: Association with periventricular leukomalacia. J Maternal-Fetal Neonatal Med. 2006;19:675–7.

    Article  Google Scholar 

  5. Amirlak I, Dawson KP. Bartter syndrome: an overview. Q J Med. 2000;93:207–15.

    Article  CAS  Google Scholar 

  6. Amorim JBO, Bailey MA, Musa-Aziz R, Giebisch G, Malnic G. Role of luminal anion and pH in distal tubule potassium secretion. Am J Physiol. 2003;284:F381–8.

    CAS  Google Scholar 

  7. Seed AE. Maternal-fetal acid-base relationships and fetal scalp-blood analysis. Clin Obstet Gynecol. 1978;21:579–91.

    Article  Google Scholar 

  8. Yoon SH, Zuccarello M, Rapoport RM. pCO2 and pH regulation of cerebral blood flow. Front Physiol. 2012;3:365.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Watanabe K, Hayakawa F, Okumura A. Neonatal EEG: A powerful tool in the assessment of brain damage in preterm infants. Brain Dev. 1999;21:361–72.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Neonatology, KK Women’s and Children’s Hospital, 100, Bukit Timah Road, Singapore, 229899, Singapore

    Shrenik Vora, Thowfique Ibrahim & Victor Samuel Rajadurai

Authors
  1. Shrenik Vora
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  2. Thowfique Ibrahim
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  3. Victor Samuel Rajadurai
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Corresponding author

Correspondence to Shrenik Vora.

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Cite this article

Vora, S., Ibrahim, T. & Rajadurai, V.S. Maternal pseudo-Bartter syndrome associated with severe perinatal brain injury. Indian Pediatr 54, 771–773 (2017). https://doi.org/10.1007/s13312-017-1173-4

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  • DOI: https://doi.org/10.1007/s13312-017-1173-4

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