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Necrotizing polyarteritis nodosa-like vasculitis in a child with systemic lupus erythematosus

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Abstract

A 10-year-old child presented with prolonged fever, lymphadenopathy, weight loss, oral ulcers, alopecia and parotitis. She later developed arterial thrombosis, poly-serositis, nephritis, myocarditis, sacro-ilitis, autoimmune hemolytic anemia and refractory thrombocytopenia. Though anti-dsDNA was negative, she was diagnosed to have systemic lupus erythematosus (SLE). Terminally, she had pulmonary symptoms and succumbed to her illness. The autopsy showed lupus nephritis-Class II, polyserositis, myocarditis, inflammatory myositis, immune mediated vasculitis involving renal, coronary, pancreatic, adrenal, dermal and intramuscular arteries, and pulmonary hemorrhages and edema.

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Authors and Affiliations

  1. Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India

    Joseph L. Matthews, Sagar Bhattad, Anju Gupta & Surjit Singh

  2. Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India

    Ritambhra Nada

Authors
  1. Ritambhra Nada
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  2. Joseph L. Matthews
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  3. Sagar Bhattad
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  4. Anju Gupta
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  5. Surjit Singh
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Nada, R., Matthews, J.L., Bhattad, S. et al. Necrotizing polyarteritis nodosa-like vasculitis in a child with systemic lupus erythematosus. Indian Pediatr 54, 139–144 (2017). https://doi.org/10.1007/s13312-017-1017-2

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  • DOI: https://doi.org/10.1007/s13312-017-1017-2

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