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Rotavirus diarrhea in children presenting to an urban hospital in Western Uttar Pradesh, India

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Abstract

Objective

To determine the proportion and clinical profile of rotavirus-associated diarrhea in children aged 6 months to 5 years.

Methods

Clinical details and stool samples were collected from 254 children aged between 6 months to 5 years presenting with acute diarrhea, irrespective of hydration status, to the outpatient department or emergency room of a hospital in Meerut, Uttar Pradesh, India.

Results

Rotavirus accounted for 26.3% (51 of 194) of diarrhea cases overall, and 41.2% (14 of 34) in hospitalized children. Rotavirus infection was associated with significantly longer duration [3.3 (1.4) d vs. 2.5 (1.1) d; P=0.004) of diarrhea, and more chances of dehydration (OR 1.85; 95% CI 1.19, 3.57) as compared to non-rotavirus diarrhea.

Conclusion

Rotavirus is a common cause of acute diarrhea in under-five children, and is associated with a longer duration and more chances of dehydration than non-rotavirus diarrhea.

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References

  1. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095–128.

    Article  PubMed  Google Scholar 

  2. Tate JE, Chitambar S, Esposito DH, Sarkar R, Gladstone B, Ramani S, et al. Disease and economic burden of rotavirus diarrhoea in India. Vaccine. 2009;27:18–24.

    Article  Google Scholar 

  3. Kahn G, Fitzwater S, Tate J, Kang G, Ganguly N, Nair G, et al. Epidemiology and prospects for prevention of rotavirus disease in India. Indian Pediatr. 2012;49: 467–74.

    Article  CAS  PubMed  Google Scholar 

  4. Kang G, Arora R, Chitambar SD, Deshpande J, Gupte MD, Kulkarni M, et al. Multicenter, hospital-based surveillance of rotavirus disease and strains among Indian children aged <5 years. J Infect Dis. 2009;200:147–53.

    Article  Google Scholar 

  5. Morris SK, Awasthi S, Khera A, Bassani DG, Kang G, Parashar UD, et al. Rotavirus mortality in India: Estimates based on a nationally representative survey of diarrhoeal deaths. Bull World Health Organ. 2012;90: 720–7.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Arora NK, Das MK, Mathur P. Diseases of Gastrointestinal Tract and Liver. In: Ghai OP, Paul VK, Bagga A, editors. Ghai Essential Pediatrics. 7th ed. Delhi: CBS Publishers; 2009. p. 251–95.

    Google Scholar 

  7. Aggarwal S, Upadhyay A, Shah D, Teotia N, Agarwal A, Jaiswal V. Lactobacillus GG for treatment of acute childhood diarrhoea: An open labelled, randomized controlled trial. Indian J Med Res. 2014;139:379–85.

    PubMed  PubMed Central  Google Scholar 

  8. Bahl R, Ray P, Subodh S, Shambharkar P, Saxena M, Parashar U, et al. Incidence of severe rotavirus diarrhea in New Delhi, India, and G and P types of infecting strains. J Infect Dis. 2005;192:114–9.

    Article  Google Scholar 

  9. Banerjee I, Ramani S, Primrose B, Moses P, Iturriza-Gomara M, Gray JJ, et al. Comparative study of the epidemiology of rotavirus in children from a communitybased birth cohort and a hospital in South India. J Clin Microbiol. 2006;44:2468–74.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Ramani S, Kang G. Burden of disease and molecular epidemiology of group A rotavirus infections in India. Indian J Med Res. 2007;125:619–32.

    CAS  PubMed  PubMed Central  Google Scholar 

  11. Gladstone BP, Ramani S, Mukhopadhya I, Muliyil J, Sarkar R, Rehman AM, et al. Protective effect of natural rotavirus infection in an Indian birth cohort. N Engl J Med. 2011;365:337–46.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Correspondence to Neeraj Teotia.

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Teotia, N., Upadhyay, A., Agarwal, S. et al. Rotavirus diarrhea in children presenting to an urban hospital in Western Uttar Pradesh, India. Indian Pediatr 53, 627–629 (2016). https://doi.org/10.1007/s13312-016-0899-8

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  • DOI: https://doi.org/10.1007/s13312-016-0899-8

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