Abstract
Objective
To estimate the burden of rotavirus-associated gastroenteritis in India.
Methods
Hospital-based surveillance network was established, with clinical evaluation and laboratory testing for rotavirus among children aged below 5 years hospitalized with acute gastroenteritis.
Results
Between September 2012 and December 2014, stool samples from 10207 children were tested and rotavirus was detected in 39.6% of cases. Infections were more commonly seen among younger children (<2 years). Detection rates were higher during cooler months of September–February. Among rotavirus infected-children, 64.0% had severe or very severe disease. G1P[8] was the predominant rotavirus genotype (62.7%) observed during the surveillance period.
Conclusions
Surveillance data highlights the high rotavirus disease burden and emphasizes the need for close monitoring to reduce morbidity and mortality associated with rotavirus gastroenteritis in India.
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References
World Health Organization. Rotavirus Mortality Estimates. Available from: http://www.who.int/immunization/monitoring_surveillance/burden/estimates/rotavirus/en. Accessed March 21, 2016.
John J, Sarkar R, Muliyil J, Bhandari N, Bhan MK, Kang G. Rotavirus gastroenteritis in India, 2011-2013: Revised estimates of disease burden and potential impact of vaccines. Vaccine. 2014;32:A5–9.
World Health Organization. Generic protocols (i) hospitalbased surveillance to estimate the Burden of Rotavirus Gastroenteritis in Children and (ii) a Community Based Survey on Utilization of Health Care Services for Gastroenteritis in Children. Geneva. 2002.
Mehendale S, Venkatasubramanian S, Girish Kumar CP, Kang G, Gupte MD, Arora R. Expanded Indian National Rotavirus Surveillance Network in the context of rotavirus vaccine introduction. Indian Pediatr.2016;53:575–81.
Kang G, Desai R, Arora R, Chitambar S, Naik TN, Krishnan T, et al. Diversity of circulating rotavirus strains in children hospitalized with diarrhea in India, 2005–2009. Vaccine. 2013;31:2879–83.
Kang G, Arora R, Chitambar SD, Deshpande J, Gupte MD, Kulkarni M, et al. Multicenter, hospital-based surveillance of rotavirus disease and strains among Indian children aged <5 years. J Infect Dis. 2009;200:S147–S53.
Saluja T, Sharma SD, Gupta M, Kundu R, Kar S, Dutta A, et al. A multicenter prospective hospital-based surveillance to estimate the burden of rotavirus gastroenteritis in children less than five years of age in India. Vaccine. 2014;32:A13–9.
Brandt CD, Kim HW, Rodriguez WJ, Arrobio JO, Jeffries BC, Parrott RH. Rotavirus gastroenteritis and weather. J Clin Microbiol. 1982;16:478–82.
Jagai JS, Sarkar R, Castronovo D, Kattula D, McEntee J, Ward H, et al. Seasonality of rotavirus in South Asia: A meta-analysis approach assessing associations with temperature, precipitation, and vegetation index. PLoS ONE. 2012;7:e38168.
Ministry of Health and Family Welfare Notable Achievements and Initiatives-2015. Press Information Bureau. Available from: http://pib.nic.in/newsite/Print Release.aspx?relid=133853. Accessed March 21, 2016.
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Girish Kumar, C.P., Venkatasubramanian, S., Kang, G. et al. Profile and trends of rotavirus gastroenteritis in under-five children in India (2012-2014): Preliminary report of the Indian national rotavirus surveillance network. Indian Pediatr 53, 619–622 (2016). https://doi.org/10.1007/s13312-016-0897-x
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DOI: https://doi.org/10.1007/s13312-016-0897-x