Skip to main content

Sclerosing angiomatoid nodular transformation of spleen in a 3-year-old child

Indian Pediatrics volume 52, pages 1081–1083 (2015)Cite this article

Abstract

Background

Reports of sclerosing angiomatoid nodular transformation in the pediatric population are rare.

Case characteristics

The 3-year-old child was injured in a car accident and then diagnosed with sclerosing angiomatoid nodular transformation. The patient underwent exploratory surgery with partial splenectomy including total excision of the tumor mass.

Outcome

Neither recurrence nor metastasis occurred over 20 months of follow-up.

Message

Sclerosing angiomatoid nodular transformation can occur in early childhood.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

References

  1. Martel M, Cheuk W, Lombardi L, Lifschitz-Mercer B, Chan JK, Rosai J. Sclerosing angiomatoid nodular transformation (SANT): Report of 25 cases of a distinctive benign splenic lesion. Am J Surg Pathol. 2004,28:1268–79.

    PubMed  Article  Google Scholar 

  2. Budzyñski A, Demczuk S, Kumiega B, Migaczewski M, Mat³ok M, Zub-Pokrowiecka A. Sclerosing angiomatoid nodular transformation of the spleen treated by laparoscopic partial splenectomy. Videosurgery and Other Miniinvasive Techniques. 2011;6: 249–55.

    PubMed  PubMed Central  Article  Google Scholar 

  3. Bamboat ZM, Masiakos PT. Sclerosing angiomatoid nodular transformation of the spleen in an adolescent with chronic abdominal pain. J Pediatr Surg. 2010;45:E13–6.

    PubMed  Article  Google Scholar 

  4. Vyas M, Deshmukh M, Shet T, Jambhekar N. Splenic angiomatoid nodular transformation in child with inflammatory pseudotumor-like areas. Indian J Pathol Microbiol. 2011;54:829–31.

    PubMed  Google Scholar 

  5. Hou J, Ji Y, Tan YS, Shi DR, Liu YL, Xu C, et al. Sclerosing angiomatoid nodulartransformation of spleenÿa clinicopathologic study of 10 cases with review of literature. Chin J Pathol. 2010;39:84–7.

    Google Scholar 

  6. Zhang MQ, Lennerz JK, Dehner LP. Granulomatous inflammatory pseudotumor of the spleen: association with Epstein-Barr virus. Appl Immunohistochem Mol Morphol. 2009;17:259–63.

    PubMed  Article  Google Scholar 

  7. Falk GA, Nooli NP, Morris-Stiff GÿPlesec TP, Rosenblatt S. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen: Case report and review of the literature. Int J Surg Case Rep. 2012;3:492–500.

    PubMed  PubMed Central  Article  Google Scholar 

  8. Li L, Fisher DA, Stanek AE. Sclerosing angiomatoid nodular transformation (SANT) of the spleen: addtion of a case with focal CD68 staining and distinctive CT features. Am J Surg Pathol. 2005;29:839–41.

    PubMed  Article  Google Scholar 

  9. Zeeb LM, Johnson JM, Madsen M S, Keating DP. Sclerosing angiomatoid nodular transformation. Am J Roentgenol. 2009;192:W236–8.

    Article  Google Scholar 

  10. Thacker C, Korn R, Millstine J, Harvin H, Van Lier Ribbink JA, Gotway MB. Sclerosing angiomatoid nodular transformation of the spleen: CT,MR,PET, and 99mTcsulfur colloid SPECT CT findings with gross and histopathological correlation. Abdom Imaging. 2010;35:683–9.

    PubMed  PubMed Central  Article  Google Scholar 

Download references

Author information

Affiliations

  1. From Departments of Pathology, Jiangxi Children’s Hospital, Nanchang, 330006, China

    Shouhua Zhang, Wenping Yang & Hongyan Xu

  2. General Surgery, Jiangxi Children’s Hospital, Nanchang, 330006, China

    Zhuqiang Wu

Authors
  1. Shouhua Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wenping Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hongyan Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zhuqiang Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Wenping Yang.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Zhang, S., Yang, W., Xu, H. et al. Sclerosing angiomatoid nodular transformation of spleen in a 3-year-old child. Indian Pediatr 52, 1081–1083 (2015). https://doi.org/10.1007/s13312-015-0776-x

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-015-0776-x

Keywords

  • Abdominal pain
  • Neoplasms
  • Splenectomy