Skip to main content

Acute kidney injury following plastic bronchitis associated with influenza B virus in a child with nephrotic syndrome

Abstract

Background

Plastic bronchitis is a rare but life-threatening disorder and is usually associated with congenital heart disease or pulmonary disease.

Case characteristics

A 5-year-old boy with minimal change nephrotic syndrome who developed a relapse along with cough, fever and dyspnea. Observation: Chest X-ray showed atelectasis of right upper lobe of lung, and nasal swab was positive for influenza B virus. His respiratory condition worsened, and required ventilation; bronchoscopy revealed bronchial casts. This was followed by acute kidney injury which was successfully managed with hemodialysis.

Message

Children with nephrotic syndrome on immunosuppressive agents can develop plastic bronchitis and acute kidney injury, following influenza virus infection.

This is a preview of subscription content, access via your institution.

References

  1. Brogan TV, Finn LS, Pyskaty DJ, Redding GJ, Ricker D, Inglis A, et al. Plastic bronchitis in children: A case series and review of the medical literature. Pediatr Pulmonol. 2002;34:482–7.

    PubMed  Article  Google Scholar 

  2. Deng J, Zheng Y, Li C, Ma Z, Wang H, Rubin BK. Plastic bronchitis in three children associated with 2009 influenza A (H1N1) virus infection. Chest. 2010;138: 1486–8.

    PubMed  Article  Google Scholar 

  3. Hasegawa M, Inamo Y, Fuchigami T, Hashimoto K, Morozumi M, Ubukata K, et al. Bronchial casts and pandemic (H1N1) 2009 virus infection. Emerg Infect Dis. 2010;16:344–6.

    PubMed Central  PubMed  Article  Google Scholar 

  4. Terano C, Miura M, Fukuzawa R, Saito Y, Arai H, Sasaki M, et al. Three children with plastic bronchitis associated with 2009 H1N1 influenza virus infection. Pediatr Infect Dis J. 2011;30:80–2.

    PubMed  Article  Google Scholar 

  5. Ding XF, Zhong LL, Zhang B, Lin L, Huang H, Liang M. Clinical features and pathogens of plastic bronchitis in children: an analysis of 9 cases. Zhongguo Dang Dai Er Ke Za Zhi. 2014;16:729–33.

    PubMed  Google Scholar 

  6. Stiller B, Riedel F, Paul K, van Landeghem FKH. Plastic bronchitis in children with Fontan palliation: Analogue to protein losing enteropathy? Pediatr Cardiol. 2002;23:90–4.

    CAS  PubMed  Article  Google Scholar 

  7. Rychik J, Goldberg D, Rand E, Semeao E, Russo P, Dori Y, et al. End-organ consequences of Fontan operation: Liver fibrosis, protein-losing enteropathy and plastic bronchitis. Cardiol Young. 2013;23:831–40.

    PubMed  Article  Google Scholar 

  8. Seear M, Hui H, Magee F, Bohn D, Cutz E. Bronchial casts in children: A proposed classification based on nine cases and a review of the literature. Am J Respir Crit Care Med. 1997;155:364–70.

    CAS  PubMed  Article  Google Scholar 

  9. Agarwal N, Phadke KD, Garg I, Alexander P. Acute renal failure in children with idiopathic nephrotic syndrome. Pediatr Nephrol. 2003;18:1289–92.

    PubMed  Article  Google Scholar 

  10. MacDonald NE, Wolfish N, McLaine P, Phipps P, Rossier E. Role of respiratory viruses in exacerbations of primary nephrotic syndrome. J Pediatr. 1986;108: 378–82.

    CAS  PubMed  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Shuichiro Fujinaga.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Fujinaga, S., Hara, T. Acute kidney injury following plastic bronchitis associated with influenza B virus in a child with nephrotic syndrome. Indian Pediatr 52, 523–525 (2015). https://doi.org/10.1007/s13312-015-0669-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-015-0669-z

Keywords

  • Acute kidney injury
  • Influenza B virus
  • Minimal change nephrotic syndrome