Abstract
The eleven member states of World Health Organization South-East Asia Region committed to eliminate measles by 2020. In phased manner, Government of India is working on this goal, and has introduced two-dose strategy for measles vaccine in the routine immunization. Molecular epidemiology of measles in India has been considerably growing that would be useful for understanding the circulation of wild type measles in pre- and post-elimination period. However, importations of cases from other countries may be likely. This article describes major challenges to achieve the measles elimination goal in India.
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References
World Health Organization SEARO. Measles Elimination by 2020. Available from: http://www.searo.who.int/mediacentre/releases/2013/pr1565. Accessed July 18, 2014.
World Health Organization. Measles vaccines: WHO position paper. Wkly Epidemiol Rec. 2009;84:349–60.
Press Information Bureau, Government of India. Prime Minister’s Office 03-July-2014 16:31 IST. Available from: http://pib.nic.in/newsite/PrintRelease.aspx?relid=106055. Accessed September 30, 2014.
Indian Academy of Pediatrics, Advisory Committee on Vaccines and Immunization Practices (ACVIP), Vashishtha VM, Yewale VN, Bansal CP, Mehta PJ. IAP perspectives on measles and rubella elimination strategies. Indian Pediatr. 2014;51:719–22.
Centers for Disease Control and Prevention (CDC). Progress in implementing measles mortality reduction strategies—India, 2010–2011. Morb Mortal Wkly Rep. 2011;60:1315–9.
Simons E, Ferrari M, Fricks J, Wannemuehler K, Anand A, Burton A, et al. Assessment of the 2010 global measles mortality reduction goal: Results from a model of surveillance data. Lancet. 2012;379:2173–8.
Murhekar MV, Ahmad M, Shukla H, Abhishek K, Perry RT, Bose AS, et al. Measles case fatality rate in Bihar, India, 2011–12. PLoS One. 2014;9:e96668.
Sudfeld CR, Halsey NA. Measles case fatality ratio in India a review of community based studies. Indian Pediatr. 2009;46:983–9.
Morris SK, Awasthi S, Kumar R, Shet A, Khera A, Nakhaee F, et al. MDS Collaborators. Measles mortality in high and low burden districts of India: Estimates from a nationally representative study of over 12,000 child deaths. Vaccine. 2013;31:4655–61.
Garg S, Laskar AR. Measles elimination goal: Is it feasible for India? Indian J Public Health. 2010;54:190–3.
Gupta SK, Sosler S, Haldar P, Hombergh Hv, Bose AS. Introduction strategy of a second dose measles containing vaccine in India. Indian Pediatr. 2011;48:379–82.
Bhuniya S, Maji D, Mandal D, Mondal N. Measles outbreak among the Dukpa tribe of Buxa hills in West Bengal, India: Epidemiology and vaccine efficacy. Indian J Public Health. 2013;57:272–5.
Mishra PP, Chauhan NT. Double outbreak of measles in the Talaja block of Bhavnagar district, Gujarat, India 2011: A need for improving the vaccine coverage and the community participation. J Clin Diagn Res. 2012;6:1713–7.
Murhekar MV, Hutin YJ, Ramakrishnan R, Ramachandran V, Biswas AK, Das PK, et al. The heterogeneity of measles epidemiology in India: implications for improving control measures. J Infect Dis. 2011;204:S421–6.
Wairagkar N, Chowdhury D, Vaidya S, Sikchi S, Shaikh N, Hungund L, et al. MeaslesNetIndia collaborators. Molecular epidemiology of measles in India, 2005–2010. J Infect Dis. 2011;204:S403–13.
Vaidya SR, Wairagkar NS, Raja D, Khedekar DD, Gunasekaran P, Shankar S, et al. First detection of measles genotype D7 from India. Virus Genes. 2008;36:31–4.
Shakya AK, Shukla V, Maan HS, Dhole TN. Identification of different lineages of measles virus strains circulating in Uttar Pradesh, North India. Virol J. 2012;9:237.
Shakya AK, Shukla V, Maan HS, Dhole TN. Epidemiology and genetic relatedness of measles virus infection in Uttar Pradesh, India, during 2009–2010. Arch Virol. 2012,157:723–31.
Ramamurty N, Raja D, Gunasekaran P, Varalakshmi E, Mohana S, Jin L. Investigation of measles and rubella outbreaks in Tamil Nadu, India-2003. J Med Virol. 2006;78:508–13.
Kuttiatt VS, Kalpathodi S, Gangadharan ST, Kailas L, Sreekumar E, Sukumaran SM, et al. Detection of measles virus genotype B3, India. Emerg Infect Dis. 2014;20:1764–6.
Bhargava I, Chhaparwal BC, Phadke MA, Irani SF, Chhaparwal D, Dhorje S, et al. Immunogenicity and reactogenicity of indigenously produced MMR vaccine. Indian Pediatr. 1995;32:983–8.
Raut SK, Kulkarni PS, Phadke MA, Jadhav SS, Kapre SV, Dhere RM, et al. Persistence of antibodies induced by measles-mumps-rubella vaccine in children in India. Clin Vaccine Immunol. 2007;14:1370–1.
Gomber S, Arora SK, Das S, Ramachandran VG. Immune response to second dose of MMR vaccine in Indian children. Indian J Med Res. 2011;134:302–6.
Arunkumar G, Vandana KE, Sathiakumar N. Prevalence of measles, mumps, rubella, and varicella susceptibility among health science students in a University in India. Am J Ind Med. 2013;56:58–64.
Vaidya SR, Brown DW, Jin L, Samuel D, Andrews N, Brown KE. Development of a focus reduction neutralization test (FRNT) for detection of mumps virus neutralizing antibodies. J Virol Methods. 2010;163:153–6.
Vaidya SR, Kumbhar NS, Bhide VS. Detection of measles, mumps and rubella viruses by immuno-colorimetric assay and its application in a focus reduction neutralization tests. Microbiol Immunol. 2014;58:666–74.
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Vaidya, S.R. Commitment of measles elimination by 2020: Challenges in India. Indian Pediatr 52, 103–106 (2015). https://doi.org/10.1007/s13312-015-0580-7
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DOI: https://doi.org/10.1007/s13312-015-0580-7


