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Risk factors associated with Methicillin-resistant Staphylococcus aureus infection in children

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Abstract

Objective

To identify the clinical variables that differentiate MRSA (Methicillin-resistant Staphylococcus aureus) from MSSA (Methicillin-sensitive S. aureus) infection.

Methods

Cases having culture isolates of Staphylococcus species were recruited. Baseline and other laboratory parameters were compared between MSSA and MRSA sub-groups to identify the predictors for MRSA.

Results

Out of 98 isolates of S.aureus, 46 (47%) were MRSA. Significant leukocytosis was found in cases with MRSA (P <0.03). None of the other clinical variables could differentiate MRSA from MSSA infection.

Conclusion

Presence of leukocytosis was twice more likely to predict MRSA than MSSA at admission. Empiric therapy must be guided by antimicrobial sensitivity pattern of regional culture isolates.

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Authors and Affiliations

  1. Departments of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), 605006, Pondicherry, India

    Kandasamy Senthilkumar & Niranjan Biswal

  2. Departments of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India

    Sujatha Sistla

Authors
  1. Kandasamy Senthilkumar
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  2. Niranjan Biswal
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  3. Sujatha Sistla
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Corresponding author

Correspondence to Niranjan Biswal.

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Senthilkumar, K., Biswal, N. & Sistla, S. Risk factors associated with Methicillin-resistant Staphylococcus aureus infection in children. Indian Pediatr 52, 31–33 (2015). https://doi.org/10.1007/s13312-015-0562-9

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  • DOI: https://doi.org/10.1007/s13312-015-0562-9

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