Abstract
This case-series analyzed the outcome of live donor liver transplantation (LT) performed in children <7.5kg from January 2008 to June 2009 at our center. Five patients (3 males, 2 females, mean age, 8.2 ±.4 months; mean weight 6.8 ± 0.4 kg) underwent LT. The indications of LT included biliary atresia (3) and idiopathic neonatal hepatitis (2). Postoperative complications included acute rejection (1), portal venous thrombosis (1), bile leak (1), severe hypertension (1) and bacterial sepsis (4). There were no donor related complications. The median follow-up duration is 11 months with patient and graft survival rates of 100% each, respectively.
References
Shneider BL, Mazariegos GV. Biliary atresia: a transplant perspective. Liver Transpl. 2007;13:1482–1495.
Karakayali H, Ozcay F, Sevmis S, Savas N, Haberal M. Liver transplantation for small babies. Transplant Proc. 2007;39:1153–1156.
Lucianetti A, Guizzetti M, Bertani A, Corno V, Maldini G, Pinelli D, et al. Liver transplantation in children weighting less than 6 kg: The Bergamo Experience. Transplantation Proceedings. 2005;37:1143–1145.
Darwish AA, Bourdeaux C, Kader HA, Janssen M, Sokal E, Lerut J, et al. Pediatric liver transplantation using left hepatic segments from living related donors: surgical experience in 100 recipients at Saint-Luc University Clinics. Pediatr Transplant. 2006;10:345–343.
Saad S, Tanaka K, Inomata Y, Uemoto S, Ozaki N, Okajima H, et al. Portal vein reconstruction in pediatric liver transplantation from living donors. Ann Surg. 1998; 227:275–281.
Kumar N, Atkison P, Fortier MV, Grant DR, Wall WJ. Cavoportal transposition for portal vein thrombosis in a pediatric living-related liver transplantation. Liver Transpl. 2003;9:874–876.
Poonacha P, Sibal A, Soin AS, Rajashekar MR, Rajakumari DV. India’s first successful pediatric liver transplantation. Indian Pediatr. 2001;38:287–291.
Kim JS, Groteluschen R, Mueller T, Ganschow R, Bicak T. Wilms C, et al. Pediatric transplantation: the Hamburg experience. Transplantation. 2005;79:1206–1209.
Haberal M, Sevmis S, Karakayali H, Ozcay F, Moray G, Yilmaz U, et al. Pediatric liver transplant: results of a single center. Exp Clin Transplant. 2008;6:7–13.
Jain A, Mazariegos G, Kashyap R. Pediatric liver transplantation. A single center experience spann-ing 20 years. Transplantation. 2002;73:941–947.
Bucuvalas JC, Zeng L, Anand R. Studies of Pediatric Liver Transplantation Research Group. Predictors of length of stay for pediatric liver transplant recipients. Liver Transpl. 2004;10:1011–1017.
Kelly DA, Sibal A. Liver transplantation in children. Indian Pediatr. 2006;43:389–391.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kaur, S., Wadhwa, N., Sibal, A. et al. Outcome of live donor liver transplantation in indian children with bodyweight <7.5 kg. Indian Pediatr 48, 51–54 (2011). https://doi.org/10.1007/s13312-011-0024-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13312-011-0024-y