Skip to main content

Advertisement

Log in

Laparoscopic surgical technique for left intrahepatic cholangiocarcinoma with lymph node metastasis after conversion therapy (with video)

  • Technical Note
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

Intrahepatic cholangiocarcinoma (ICC) with lymph node metastasis has a poor clinical prognosis. Comprehensive surgical treatment based on surgery is critical for improving the prognosis. Conversion therapy provides an opportunity for radical surgery in such patients but also increases the difficulty of surgery. The technical barrier to laparoscopic lymph node dissection is determining the extent of regional lymph node dissection after conversion therapy and formulating a suitable procedure to ensure the quality of lymph node dissection and oncological safety. One patient with initially unresectable left ICC underwent successful conversion therapy at another hospital. Then, we performed laparoscopic left hemihepatectomy with middle hepatic vein resection and regional lymph node dissection. Specific surgical techniques are used to reduce injury and bleeding, ultimately reducing the incidence of complications and promoting rapid recovery of patients. No postoperative complications were noted. The patient recovered well; no tumor recurrence was observed during the follow-up. Preoperatively planned regional lymph node dissection provides a reference for exploring the standard laparoscopic surgical treatment of ICC. Procedural regional lymph node dissection and artery protection techniques ensure quality and oncological safety in lymph node dissection. When selecting appropriate cases, as long as the laparoscopic surgical technique is mastered, laparoscopic surgery is safe and feasible with faster postoperative recovery and less trauma for left ICC.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Data availability

The data that support the findings of this study are available on request from the corresponding author, Jian-Wei Li, upon reasonable request.

References

  1. Umeda Y, Mitsuhashi T, Kojima T et al (2022) Impact of lymph node dissection on clinical outcomes of intrahepatic cholangiocarcinoma: inverse probability of treatment weighting with survival analysis. J Hepatobiliary Pancreat Sci 29:217–229. https://doi.org/10.1002/jhbp.1038

    Article  PubMed  Google Scholar 

  2. Weber SM, Ribero D, O’Reilly EM, Kokudo N, Miyazaki M, Pawlik TM (2015) Intrahepatic cholangiocarcinoma: expert consensus statement. HPB (Oxford) 17:669–680. https://doi.org/10.1111/hpb.12441

    Article  PubMed  Google Scholar 

  3. Patrone R, Izzo F, Palaia R et al (2021) Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma: a systematic review. World J Gastrointest Oncol 13:2203–2215. https://doi.org/10.4251/wjgo.v13.i12.2203

    Article  PubMed  PubMed Central  Google Scholar 

  4. Navarro JG, Lee JH, Kang I et al (2020) Prognostic significance of and risk prediction model for lymph node metastasis in resectable intrahepatic cholangiocarcinoma: do all require lymph node dissection? HPB (Oxford) 22:1411–1419. https://doi.org/10.1016/j.hpb.2020.01.009

    Article  PubMed  Google Scholar 

  5. Zhang XF, Chen Q, Kimbrough CW et al (2018) Lymphadenectomy for intrahepatic cholangiocarcinoma: has nodal evaluation been increasingly adopted by surgeons over time? A national database analysis. J Gastrointest Surg 22:668–675

    Article  PubMed  Google Scholar 

  6. Bagante F, Spolverato G, Weiss M et al (2018) Assessment of the lymph node status in patients undergoing liver resection for intrahepatic cholangiocarcinoma: the new Eighth Edition AJCC staging system. J Gastrointest Surg 22:52–59. https://doi.org/10.1007/s11605-017-3426-x

    Article  PubMed  Google Scholar 

  7. Kim SH, Han DH, Choi GH et al (2019) Oncologic impact of lymph node dissection for intrahepatic cholangiocarcinoma: a propensity score-matched study. J Gastrointest Surg 23:538–544. https://doi.org/10.1007/s11605-018-3899-2

    Article  PubMed  Google Scholar 

  8. Yamashita YI, Wang H, Kurihara T et al (2016) Clinical significances of preoperative classification of intrahepatic cholangiocarcinoma: different characteristics of perihilar vs. peripheral ICC. Anticancer Res 36:6563–6569. https://doi.org/10.21873/anticanres.11260

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

Xing-Ru Wang and Jian-Wei Li have contributed equally to this work.

Funding

This study did not receive any funding.

Author information

Authors and Affiliations

Authors

Contributions

X-RW: study concepts and design, analysis and interpretation of data, manuscript preparation. J-WL: drafting of the manuscript, software development, technical instruction, and critical revision of the manuscript. LC: acquisition of data.

Corresponding author

Correspondence to Jian-Wei Li.

Ethics declarations

Conflict of interest

Xing-Ru Wang, Li Cao, and Jian-Wei Li have no conflicts of interest or financial ties to disclose. All authors have completed the ICMJE uniform disclosure form.

Research involving human participants and/or animals

The study was approved by the ethics committee of the First Affiliated Hospital of Army Medical University. The patient signed informed consent forms before participating in the study.

Informed consent

Written informed consent was obtained from the patients or their relatives. This study was approved by the ethics committee of First Affiliated Hospital, Army Medical University.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (MP4 495628 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, XR., Cao, L. & Li, JW. Laparoscopic surgical technique for left intrahepatic cholangiocarcinoma with lymph node metastasis after conversion therapy (with video). Updates Surg 75, 1351–1353 (2023). https://doi.org/10.1007/s13304-023-01552-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13304-023-01552-1

Keywords

Navigation