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Comparison of lateral transperitoneal versus retroperitoneal laparoscopic adrenalectomy for pheochromocytoma: a single-centre retrospective study

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Abstract

Laparoscopic adrenalectomy (LA) has became the standardized treatment for pheochromocytoma. The aim of this study was to evaluate outcomes of lateral transperitoneal and retroperitoneal LA for pheochromocytoma. Between January 2011 and December 2021, 142 patients with pheochromocytoma underwent LA via lateral transperitoneal (123 patients) or retroperitoneal (19 patients) approaches. Data of these patients were assessed to investigate the differences in perioperative outcomes and intraoperative haemodynamic parameters between the two procedures. Clinical parameters at presentation were comparable between the two groups, except for tumour size, which was larger in the transperitoneal group (50 [10–115] mm vs 35 [7–110] mm, P = 0.012). There were no significant differences between the two groups in terms of operation time, estimated blood loss, intraoperative transfusion rate, incidence of complications, conversion to open surgery, postoperative analgesic requirement, time to first oral intake, or mean hospital stay. Intraoperative haemodynamic parameters of the two groups were similar. After adjusting for tumour size using propensity score matching, both perioperative outcomes and haemodynamic parameters were still comparable. Lateral transperitoneal and retroperitoneal laparoscopic adrenalectomies provide similar perioperative and haemodynamic outcomes for surgical resection of pheochromocytoma.

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Data availability

The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

Abbreviations

CT:

Computed tomography

LA:

Laparoscopic adrenalectomy

MRI:

Magnetic resonance imaging

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Funding

This study was supported by grants from Natural Science Foundation of Shandong Province (ZR2021MH049).

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Author notes

  1. Qing-bo Zhang and Yong-sheng Huang contributed equally to this study.

Authors and Affiliations

  1. Department of Urology, Qilu Hospital, Shandong University, No 107, Wenhuaxi Road, Jinan, 250012, People’s Republic of China

    Qing-bo Zhang, Yong-sheng Huang, Lei Yan, Zhao Liu, Zhong-hua Xu & Gang-li Gu

Authors
  1. Qing-bo Zhang
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  2. Yong-sheng Huang
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  3. Lei Yan
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  4. Zhao Liu
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  5. Zhong-hua Xu
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  6. Gang-li Gu
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Contributions

Conception and design: QBZ and YSH; Perform research: QBZ, LY and ZL; Data analysis and technical support: YSH, ZHX and GLG; Manuscript writing: QBZ.

Corresponding author

Correspondence to Gang-li Gu.

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The authors declare that they have no relevant financial interests.

Ethical approval

The protocol of this research has been approved by the Ethics Committee of Qilu Hospital, Shandong University. All methods were performed in accordance with the Declaration of Helsinki.

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Zhang, Qb., Huang, Ys., Yan, L. et al. Comparison of lateral transperitoneal versus retroperitoneal laparoscopic adrenalectomy for pheochromocytoma: a single-centre retrospective study. Updates Surg 75, 1259–1266 (2023). https://doi.org/10.1007/s13304-023-01475-x

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  • DOI: https://doi.org/10.1007/s13304-023-01475-x

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