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Evolution and time trends of nipple-sparing mastectomy: a single-center experience

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Abstract

Nipple Sparing Mastectomy (NSM) requires the entire breast tissue to be removed, maintaining the nipple-areola complex, and represents nowadays the gold standard of the demolitive breast surgery. Although it represents the evolution of conservative breast surgery, NSM presents some limitations in the selection of women candidates for treatment, and still there are no real guidelines regarding its indications, but simply objective data to address the choice. How the breast surgery approach to demolitive and conservative surgery has changed over time? We evaluated throughout the years (from 2009 up to 2018) the time trend of NSM at our institution and analysed the main differences between patients undergone NSM and other mastectomies and/or breast conserving surgery in terms of cancer size, multicentricity and biological profile. We found 781 NSMs, 1261 other mastectomies and 5621 breast conservative surgeries. Among NSMs, 39.6% were reconstructed with tissue expander and 58.1% with definitive prosthesis. From 2009 to 2018 we found a general increase of NSM rate (from 21.3% of all mastectomies in 2009 to 67.3% in 2018) and a decrease of total mastectomies (from 78.7% of all mastectomies in 2009 to 32.7% in 2018). In line with the literature data, our data confirm that in the recent years NSM represents the gold standard for radical breast surgery. Undisputed in prophylaxis, NSM is continuously acquiring more support in being used as first line treatment for locally advanced disease.

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Abbreviations

NSM:

Nipple Sparing Mastectomy

NAC:

Nipple-Areola Complex

BCS:

Breast-Conserving Surgery

pCR:

Pathologic Complete Response

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Funding

All authors disclose any financial and personal relationships with other people or organizations in the writing of this paper.

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Authors and Affiliations

  1. Breast Surgery Department, Humanitas Research Hospital and Cancer Center, Rozzano, Milan, Italy

    Erika Barbieri, Alberto Bottini, Andrea Sagona, Wolfgang Gatzemeier, Giuseppe Canavese, Chiara Annunziata Pasqualina Anghelone, Emilia Marrazzo & Corrado Tinterri

  2. Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy

    Federico Frusone, Alessandro De Luca & Maria Ida Amabile

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  1. Erika Barbieri
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  2. Federico Frusone
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Correspondence to Federico Frusone.

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Barbieri, E., Frusone, F., Bottini, A. et al. Evolution and time trends of nipple-sparing mastectomy: a single-center experience. Updates Surg 72, 893–899 (2020). https://doi.org/10.1007/s13304-020-00796-5

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