Surgery or antibiotics for acute appendicitis? Take care about study’s design and methodology!
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We read with interest the recent article published in your journal by Poillucci et al. about conservative treatment in acute appendicitis. The study is a multicentric retrospective case control study with a propensity score-based matching of the patients with acute appendicitis who received surgery or antibiotic treatment . The study showed that conservative treatment when effective allowed a significant reduction in length of stay and time to return to normal activity. On the other hand, authors found that conservative treatment had an immediate failure rate of 20% and after a mean follow-up of 20 months other 20% of patients had a recurrence of acute appendicitis. Surgical treatment was associated with complications in 13.6% of the patients.
The debate about which is the best treatment in acute appendicitis is very intense and interesting. As well noticed by the authors the debate is not new and despite a discrete number of studies on this topic, we still need...
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- 5.Podda M, Serventi F, Mortola L et al (2017) A prospective non-randomized controlled, multicenter trial comparing Appendectomy and Conservative Treatment for Patients with Uncomplicated Acute Appendicitis (the ACTUAA study). Int J Colorectal Dis 32:1649–1660. https://doi.org/10.1007/s00384-017-2878-5 CrossRefPubMedGoogle Scholar