Skip to main content

Table 3 Adverse pregnancy events in pregnant women with pT1D: MDI vs. CSII

From: Evaluation of Glycaemic Control, Glucose Variability and Hypoglycaemia on Long-Term Continuous Subcutaneous Infusion vs. Multiple Daily Injections: Observational Study in Pregnancies With Pre-Existing Type 1 Diabetes

 MDI (n = 80)CSII (n = 48)P value
Gestational week at delivery37.5 ± 1.537.1 ± 1.40.15
Apgar score8.1 ± 0.98.07 ± 1.50.58
Hypertension (%, n)25 (20)12.8 (6)0.09
Preeclampsia (%, n)3.8 (3)2.1 (1)NA
Preterm delivery (%, n)17.5 (14)27.7 (13)0.17
Emergency caesarean section (%, n)16.3 (13)25.5 (12)0.2
Macrosomia (%, n)19.2 (15)14 (6)0.46
Stillbirth (%, n)2.1 (1)NA
Neonanatal hypoglycaemia (%, n)7.5 (6)10.6 (5)0.54
NICU admission (%, n)10.7 (8)17.4 (8)0.28
Neonatal hyperbilirubinaemia (%, n)30 (24)14.9 (7)0.005
Neonatal weight (g)3456.7 ± 801.43459 ± 639.40.98
LGA (%, n)50 (40)44 (21)0.59
SGA (%, n)4 (5)NA
Congenital malformation (%)NA
  1. Data are counts (percentages) or mean ± SD
  2. Significance was found for neonatal hyperbilirubinaemia in the CSII group
  3. Comparisons in boldface type indicate significant differences (p < 0.05)
  4. Because of the limited number of events, significance could not be assessed in terms of preeclampsia, stillbirth and SGA
  5. NICU neonatal intensive care unit, LGA large for gestational age, SGA small for gestational age