Atmospheric particulate matter and breast cancer survival: estrogen receptor triggered?
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To the Editor,
Recently, a study has reported the effect of ambient particulate matter (PM) on the outcome of breast cancer in the USA . The authors indicated that exposure to higher PM was significantly associated with poorer survival, particularly among females diagnosed with early-stage cancer. Actually solid data and analyses given by several studies have revealed that atmospheric PM is associated with the increased morbidity and mortality of breast cancer patients [2, 3, 4]. However, to date, the underlying mechanism was not mentioned and still remains unclear.
KeywordsAir pollution Breast cancer Cancer survival Estrogen receptor Particulate matter
This work was supported by the National Adolescents Science and Technology Innovation Award Foundation of China and the National Natural Science Foundation of China (No. 30772133; No. 81072150; No. 81172529; No. 81272903) and the Shandong Science and Technology Development Plan (No. 2012GZC22115). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
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