Tumor Biology

, Volume 36, Issue 5, pp 3191–3193 | Cite as

Atmospheric particulate matter and breast cancer survival: estrogen receptor triggered?

  • Qiang Huo
  • Chang Cai
  • Qifeng Yang
Research Commentary

To the Editor,

Recently, a study has reported the effect of ambient particulate matter (PM) on the outcome of breast cancer in the USA [1]. The authors indicated that exposure to higher PM was significantly associated with poorer survival, particularly among females diagnosed with early-stage cancer. Actually solid data and analyses given by several studies have revealed that atmospheric PM is associated with the increased morbidity and mortality of breast cancer patients [2, 3, 4]. However, to date, the underlying mechanism was not mentioned and still remains unclear.

Atmospheric PM is the major air pollutant found in northern China, including Shandong Province. Our team presented an interesting report a few months ago [ 5], and the study has been continued. As reported, we previously recruited female patients who had resided in the same cities of Shandong Province for at least 10 years prior to their diagnosis of early-stage breast cancers [ 5]. Informed consent was obtained from all...


Air pollution Breast cancer Cancer survival Estrogen receptor Particulate matter 



This work was supported by the National Adolescents Science and Technology Innovation Award Foundation of China and the National Natural Science Foundation of China (No. 30772133; No. 81072150; No. 81172529; No. 81272903) and the Shandong Science and Technology Development Plan (No. 2012GZC22115). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Compliance with ethical standards

Conflicts of interest


Ethics committee approval

For this type of study, formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2015

Authors and Affiliations

  1. 1.Department of Breast SurgeryQilu Hospital of Shandong UniversityJinanChina
  2. 2.Department of Orthopaedic SurgeryZibo Central HospitalZiboChina

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