Tumor Biology

, Volume 36, Issue 4, pp 2815–2819 | Cite as

RETRACTED ARTICLE: Augmented TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells

  • Chenggang Li
  • Zhiming Zhao
  • Zhipeng Zhou
  • Rong Liu
Research Article


Pancreatic ductal adenocarcinoma (PDAC) is an extremely malignant tumor in humans. Thus, understanding the tumorigenesis of PDAC appears to help develop efficient therapy. Here, we show that activated TGFβ receptor signaling induces apoptosis of pancreatic carcinoma cells in vitro and in vivo, suggesting that activation of TGFβ receptor signaling may prevent development of PDAC.


Pancreatic ductal adenocarcinoma TGFβ Apoptosis 


Conflicts of interest



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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2014

Authors and Affiliations

  • Chenggang Li
    • 1
  • Zhiming Zhao
    • 1
  • Zhipeng Zhou
    • 1
  • Rong Liu
    • 1
  1. 1.Department of Surgical OncologyChinese PLA General HospitalBeijingChina

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