Tumor Biology

, Volume 36, Issue 1, pp 5–6 | Cite as

Comments on Li H et al. “A systematic review of matrix metalloproteinase 9 as a biomarker of survival in patients with osteosarcoma”

  • Qingyu Zhang
  • Jianmin Li
  • Fanxiao Liu
  • Zhenfeng Li
Research Commentary

Abstract

With great interest, we read the article “A systematic review of matrix metalloproteinase 9 as a biomarker of survival in patients with osteosarcoma” (by Li H et al.). This article suggests that high expression of matrix metalloproteinase 9 (MMP-9) is associated with a poor prognosis for patients with osteosarcoma [1]. The result is encouraging. Nevertheless, some flaws existed in this meta-analysis that we would like to point out.

Keywords

Matrix metalloproteinase 9 Osteosarcoma Prognosis Meta-analysis 

References

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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2014

Authors and Affiliations

  • Qingyu Zhang
    • 1
  • Jianmin Li
    • 1
  • Fanxiao Liu
    • 2
  • Zhenfeng Li
    • 1
  1. 1.Department of OrthopedicsQilu Hospital Shandong UniversityJinanChina
  2. 2.Department of OrthopedicsProvincial Hospital affiliated to Shandong UniversityJinanChina

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