Tumor Biology

, Volume 35, Supplement 1, pp 33–50 | Cite as

Poster presentation


PP-1. Case Report: Alpha-fetoprotein-producing lung adenocarcinoma

Bauça JM (, Robles J, Morell D, Fueyo L, García A, Barceló A

BACKGROUND Alpha-fetoprotein (AFP) is usually elevated in patients with liver cancer or gonadal germ cell tumors. Some cases of extra-hepatic tumors able to produce AFP have been reported, such as ovarian and gastric. However, AFP-producing lung malignancies are rare. CASE PRESENTATION: We present a 60-year-old woman, active smoker, previously diagnosed with COPD, diabetes, osteoporosis and dyslipidemia. Both her father and uncle died from metastatic hepatocarcinoma. She visited a doctor’s office claiming sternal oppression. A chest X-ray showed a mass at the superior lobule of the right lung. Subsequent biochemical testing yielded an AFP of 9796ng/ml, whereas all other magnitudes were within normal ranges. Thoracic CT showed a heterogeneous lung mass, with slight bilateral emphysema, without lymph node invasion. Bronchial biopsy confirmed...


Epidermal Growth Factor Receptor Prostate Specific Antigen KRAS Mutation Fecal Occult Blood Testing Epidermal Growth Factor Receptor Gene 
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© International Society of Oncology and BioMarkers (ISOBM) 2014

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