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Tumor Biology

, Volume 34, Issue 5, pp 3271–3271 | Cite as

Long noncoding RNA AC096655.1-002 has been officially named as gastric cancer-associated transcript 1, GACAT1

  • Bingxiu Xiao
  • Junming Guo
Editorial

Shortly after the article entitled “Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance” published in Tumor Biology [1], the long noncoding RNA AC096655.1-002 that studied in this paper has been officially named by HUGO Gene Nomenclature Committee (HGNC). Readers can find the detail information from Human Gene Nomenclature Database (www.genenames.org/hgnc-searches). Its HGNC ID is HGNC: 48336. Its synonym is AC096655.1-002, LINC00876, “long intergenic non-protein coding RNA 876.” Its gene is located at 2q12.3.

As long noncoding RNA AC096655.1-002 was first found associated with gastric cancer, the committee has named it as “gastric cancer-associated transcript 1, GACAT1.” That is, approved symbol is GACAT1 and approved name is gastric cancer-associated transcript 1 (http://www.genenames.org/data/hgnc_data.php?hgnc_id=48336). GACAT1 has been found significantly downregulated in gastric cancer tissues compared with paired-adjacent non-tumorous tissues. Its expression level was significantly correlated with lymph node metastasis, distant metastasis, TNM stages, and differentiation [1]. These results indicated that GACAT1 may be a potential biomarker in the diagnosis of gastric carcinoma.

Notes

Conflicts of interest

None

Reference

  1. 1.
    Sun W, Wu Y, Yu X, Liu Y, Song H, Xia T, et al. Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance. Tumor Biol. 2013. doi: 10.1007/s13277-013-0821-0.Google Scholar

Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2013

Authors and Affiliations

  1. 1.Zhejiang Provincial Key Laboratory of PathophysiologyNingbo University School of MedicineNingboChina

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