Tumor Biology

, Volume 34, Issue 4, pp 2379–2382 | Cite as

Is breast cancer in young Asian women more aggressive than in Caucasians? A cross-sectional analysis

  • Muy-Kheng M. Tea
  • Lei Fan
  • James W. Delancey
  • Christine Staudigl
  • Stefan Steurer
  • Christina Lang
  • Zhi-Ming Shao
  • Christian F. Singer
Research Article

Abstract

Ethnic differences in breast cancer are well described in studies comparing Hispanic and African-American populations to Caucasian populations. The aim of this study was to analyze the biological characteristics of breast cancer (BC) in the young Asian/Han Chinese population compared to Caucasians/Central Europeans. Histopathologies of 642 invasive BC in women at the age of 40 years and younger were analyzed in China and Austria. Pearson’s chi-squared test was used to assess differences in the analyzed populations. Significantly larger BC >2 cm (p < 0.0001) and poorly differentiated BC (p = 0.02) as well as more triple-negative BC (p = 0.002) were identified among the Han Chinese group compared to the Central European group. This analysis will provide ethnic-specific insight into the biological characteristics of BC in young patients worldwide.

Keywords

Breast cancer in the young Ethnic differences China Asian breast cancer Biological characteristics 

Notes

Conflicts of interest

None

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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2013

Authors and Affiliations

  • Muy-Kheng M. Tea
    • 1
    • 2
  • Lei Fan
    • 1
  • James W. Delancey
    • 3
  • Christine Staudigl
    • 2
  • Stefan Steurer
    • 2
    • 4
  • Christina Lang
    • 2
  • Zhi-Ming Shao
    • 1
  • Christian F. Singer
    • 2
  1. 1.Department of Breast Surgery, Shanghai Cancer InstituteFudan UniversityShanghaiChina
  2. 2.Department of Obstetrics and GynecologyMedical University of ViennaViennaAustria
  3. 3.Department of Health Systems ManagementNew OrleansUSA
  4. 4.Institute for PathologyMedical University EppendorfHamburgGermany

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