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Tumor Biology

, Volume 31, Issue 4, pp 243–253 | Cite as

Emerging strategies for the identification and targeting of cancer stem cells

Research Article

Abstract

The hypothesis of cancer stem cells (CSCs) is receiving increasing interest and has become the subject of considerable debate among cancer researchers. Recent rapid progress in CSC research has encountered increasing difficulties and challenges. Understanding the biologic characteristic of CSCs is crucial to start with better identification and diagnosis based on CSC markers and eventually targeting to CSCs will undoubtedly result in improved prevention and treatment of many types of CSCs. We discuss here some of the approaching strategies that include establishing special methods of identifying CSCs and targeting therapies of CSCs.

Keywords

Cancer stem cells Challenge Strategy 

Notes

Acknowledgements

This work was supported by the Science Foundation of Southeast University (No. 9223001446), in part by the National Natural Science Foundation of China (No. 90406023), and in part by the 973 Program of China (No.2006CB933206). We also thank Dr. Lin Wang in Atlanta, GA, USA for kindly editing the manuscript.

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Copyright information

© International Society of Oncology and BioMarkers (ISOBM) 2010

Authors and Affiliations

  1. 1.Department of Pathogenic Biology and Immunology, School of Basic Medical ScienceSoutheast UniversityNanjingChina
  2. 2.School of Biological Science & Medical EngineeringSoutheast UniversityNanjingChina

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