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Genes & Genomics

, Volume 40, Issue 7, pp 701–705 | Cite as

Multivariate genome-wide association studies on tenderness of Berkshire and Duroc pig breeds

  • Dongsung Jang
  • Joon Yoon
  • Mengistie Taye
  • Wonseok Lee
  • Taehyung Kwon
  • Seunghyun Shim
  • Heebal Kim
Research Article
  • 260 Downloads

Abstract

Genome-wide association studies (GWAS) have been steadily used for identification of genomic links to disease and various economical traits. Of those traits, a tenderness of pork is one of the most important factors in quality evaluation of consumers. In this study, we use two pig breed populations; Berkshire is known for its excellent meat quality and Duroc which is known for its high intramuscular fat content in meat. Multivariate genome-wide association studies (MV-GWAS) was executed to compare SNPs of two pigs to find out what genetic variants occur the tenderness of pork. Through MV-GWAS, we have identified candidate genes and the association of biological pathways involved in the tenderness of pork. From these direct and indirect associations, we displayed the usefulness of simple statistical models and their potential contribution to improving the meat quality of pork. We identified a candidate gene related to the tenderness in only Berkshire. Furthermore, several of the biological pathways involved in tenderness in both Berkshire and Duroc were found. The candidate genes identified in this study will be helpful to use them in breeding programs for improving pork quality.

Keywords

Berkshire Duroc Multivariate GWAS Pork quality Tenderness 

Notes

Acknowledgements

This work was carried out with the support of “Cooperative Research Program for Agriculture Science & Technology Development (Project No. PJ01111501)” Rural Development Administration, Republic of Korea.

Compliance with ethical standards

Conflict of interest

Dongsung Jang declares that he/she does not have conflict of interest on the contents of manuscript. Joon Yoon declares that he/she does not have conflict of interest on the contents of manuscript. Mengistie Taye declares that he/she does not have conflict of interest on the contents of manuscript. Wonseok Lee declares that he/she does not have conflict of interest on the contents of manuscript. Taehyung Kwon declares that he/she does not have conflict of interest on the contents of manuscript. Seunghyun Shim declares that he/she does not have conflict of interest on the contents of manuscript. Heebal Kim declares that he/she does not have conflict of interest on the contents of manuscript.

Ethical approval

The regional Ethical Committees approved whole experiment and all its procedures (JNU Animal Bioethics Committee Approval Number: 2013-0009, National Institute of Animal Science’s Institutional Animal Care and Use Committee: 2009-077).

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Copyright information

© The Genetics Society of Korea and Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Interdisciplinary Program in Agricultural GenomicsSeoul National UniversitySeoulRepublic of Korea
  2. 2.Department of Natural Science, Interdisciplinary Program in BioinformaticsSeoul National UniversitySeoulRepublic of Korea
  3. 3.Department of Agricultural Biotechnology, Animal Biotechnology and Research Institute of Agriculture and Life SciencesSeoul National UniversitySeoulRepublic of Korea
  4. 4.College of Agriculture and Environmental SciencesBahir Dar UniversityBahir DarEthiopia
  5. 5.LAS Inc.Gimpo-siRepublic of Korea
  6. 6.Institute for Biomedical SciencesShinshu UniversityNaganoJapan

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