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Haemodynamics Study of Tapered Stents Intervention to Tapered Arteries

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Abstract

Purpose

In-stent restenosis (ISR) is related to local haemodynamics in the arteries after stent intervention. However, the haemodynamics of stents implanted into tapered vessels is rarely studied and remains unclear. This study aimed to study the haemodynamic performance of a stent in a tapered artery to reveal the haemodynamic differences between tapered and cylindrical stents after stent implantation and guide the stent selection for the treatment of coronary artery stenosis.

Methods

Cylindrical and tapered stents were implanted into the tapered arteries. A model of a cylindrical stent implanted into a cylindrical artery was established as the contrast model. Using the finite element method, the flow velocity and wall shear stress distribution of the three models were compared.

Results

At t1, t2, t3 and t4, the flow rate of the tapered artery with tapered stents (TT) after the implantation increased by 8.59, 3.80, 12.81 and 3.66%, respectively. In addition, the wall shear stress in the tapered arteries of TT was 23.48, 36.67, 13.00 and 8.06% higher than that of the tapered arteries with cylindrical stents (TC).

Conclusions

The implantation of a tapered stent in the tapered artery can effectively improve intravascular haemodynamics. The tapered stent allows the tapered artery to obtain better haemodynamics and reduces the probability of ISR.

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Acknowledgments

This project is supported by National Natural Science Foundation of China (51305171), Natural Science Foundation of Jiangsu Province (BK20130525), Natural Science Foundation of the Higher Education Institutions of Jiangsu Province (13KJB460006), China Postdoctoral Science Foundation (2011M500858), Foundation of Jiangsu University (10JDG123) and Project of Jiangsu University for training young backbone teachers.

Conflict of interest

Xiang Shen, Jiabao Jiang, Yongquan Deng, Hongfei Zhu, and Kaikai Lu declare that they have no conflict of interest.

Ethical Standards

This article does not contain any studies with human participants or animals performed by any of the authors.

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Authors and Affiliations

  1. School of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, Jiangsu, China

    Xiang Shen, Jiabao Jiang, Yongquan Deng, Hongfei Zhu & Kaikai Lu

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  1. Xiang Shen
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  2. Jiabao Jiang
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  3. Yongquan Deng
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Correspondence to Xiang Shen.

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Associate Editor Hwa Liang Leo oversaw the review of this article.

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Shen, X., Jiang, J., Deng, Y. et al. Haemodynamics Study of Tapered Stents Intervention to Tapered Arteries. Cardiovasc Eng Tech 10, 583–589 (2019). https://doi.org/10.1007/s13239-019-00437-y

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  • DOI: https://doi.org/10.1007/s13239-019-00437-y

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