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Antimicrobial Activity of Polymeric Microfibers Containing Coix Lacryma-Jobi Extract

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An Erratum to this article was published on 12 October 2020

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Abstract

Wound dressings are based on the creation of ideal environments for cell mobility, gas exchanges and to promote tissue healing and regeneration, besides controlling bacterial proliferation. Electrospinning is a simple, cheap and common technique used for such purposes and Ecovio®, a polymeric blend based on biocompatible polymers (poly(butylene adipate-co-terephthalate) (PBAT) and poly(lactic acid) (PLA)), is a good example of polymer with unique properties for wound dressing materials development. To ensure antimicrobial properties, Job’s tears (Coix lacrymajobi) extract was incorporated into the material. The obtained fiber mats were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), X-ray diffractometry (DRX), optical microscopy (OM), and microbiological analysis. The interaction among the compounds of the extract and the polymeric matrix was inferred by the increase in the crystallinity degree and thermal stability of the fibers/extract. Also, a decrease in the diameter, roughness, and fiber homogeneity was observed. It happened due to the presence of extract in the fibers. Microbiological analysis (antimicrobial activity against S. aureus) indicated the effectiveness of the fibers/extract in preventing this bacteria growth, demonstrating the potential of this material for wound dressing purposes.

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Change history

  • 12 October 2020

    The 8th author���s name should be corrected as follows: Edvani Curti Muniz

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Authors and Affiliations

  1. Center of Engineer and Exact Sciences, State University of West Parana, 85903-000, Toledo, PR, Brazil

    Gabriela Lauer Breitenbach, Andressa Giombelli Rosenberger, Josiane Caetano, Desirée Tamara Scheidt, Cleide Viviane Buzanello Martins & Douglas Cardoso Dragunski

  2. Department of Biosciences, Federal University of Parana, 85950-000, Palotina, PR, Brazil

    Marina Giombelli Rosenberger

  3. Department of Chemistry, State University of Maringa, 87020-900, Maringa, PR, Brazil

    Michelly Cristina Galdioli Pellá & Edvani Curti Munizc

  4. Department of Chemistry, Federal University of Piaui, 64049-550, Teresina, PI, Brazil

    Edvani Curti Munizc

  5. Material Sci. and Eng. Post-graduation Progr., Federal University of Technology, Parana, 87036-370, Londrina, PR, Brazil

    Edvani Curti Munizc

Authors
  1. Gabriela Lauer Breitenbach
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  2. Marina Giombelli Rosenberger
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  3. Andressa Giombelli Rosenberger
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  4. Josiane Caetano
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  5. Michelly Cristina Galdioli Pellá
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  6. Desirée Tamara Scheidt
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  7. Cleide Viviane Buzanello Martins
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  8. Edvani Curti Munizc
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  9. Douglas Cardoso Dragunski
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Correspondence to Douglas Cardoso Dragunski.

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Acknowledgments: This study was supported by UNIOESTE (Campus Toledo-PR, Brazil) and UFPR (Sector Palotina-PR, Brazil). The authors would like to thank both Brazilian official agencies CNPq and CAPES for financial support and fellowships.

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Breitenbach, G.L., Rosenberger, M.G., Rosenberger, A.G. et al. Antimicrobial Activity of Polymeric Microfibers Containing Coix Lacryma-Jobi Extract. Macromol. Res. 28, 869–876 (2020). https://doi.org/10.1007/s13233-020-8115-z

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  • DOI: https://doi.org/10.1007/s13233-020-8115-z

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