A new antimicrobial polyelectrolyte polymer was prepared based on chitosan and alternating styrene maleic anhydride (SMA) copolymer. The SMA was subjected to alkaline hydrolysis, followed by blending with chitosan and chitosan in the nano form which has been prepared by self-assembly technique with particle size 46±0.08 nm. The composition was investigated and characterized by spectral and, thermogravimetric analysis, dynamic light scattering, and transmission electron microscopy. The nano polyelectrolyte complexes and composite were screened for their antimicrobial behavior and showed excellent antifungal as well as antibacterial efficacy against four bacterial and fungal strains. The hydrolyzed styrene maleic anhydride-nano-chitosan exhibited higher antimicrobial activity than the hydrolyzed styrene maleic anhydride-chitosan.
S. S. Elkholy, K. D. Khalil, and M. Z. Elsabee, J. Appl. Polym. Sci., 99, 3308 (2006).CrossRefGoogle Scholar
(10).
S. Elkholy, K. D. Khalil, M. Z. Elsabee, and M. Eweis, J. Appl. Polym. Sci., 103, 1651 (2007).CrossRefGoogle Scholar
(11).
L. Qi, Z. Xu, X. Jiang, C. Hu, and X. Zou, Carbohydr. Res., 339, 2693 (2004).CrossRefGoogle Scholar
(12).
A. Sorrentino, G. Gorrasi, and V. Vittoria, Trends Food Sci. Technol., 18, 84 (2007).CrossRefGoogle Scholar
(13).
L. E. Chavez de Paz, A. Resin, K. A. Howard, D. S. Sutherland, and P. L. Wejse, Appl. Environ. Microbiol., 77, 3892 (2011).CrossRefGoogle Scholar
(14).
M. Z. Elsabee and E. S. Abdou, Mater. Sci. Eng. C, 33, 1819 (2013).CrossRefGoogle Scholar
(15).
A. Hebeish, S. Sharaf, and A. Farouk, Int. J. Biol. Macromol., 60, 10 (2013).CrossRefGoogle Scholar
(16).
S. W. Ali, M. Joshi, and S. Rajendran, Int. J. Nanosci., 10, 979 (2011).CrossRefGoogle Scholar
(17).
K. Vellingiri, T. Ramachandran, and M. Senthilkumar, Nanosci. Nanotechnol. Lett., 5, 519 (2013).CrossRefGoogle Scholar
(18).
M. R. Noor El-Din, R. E. Morsi, and M. Z. Elsabee, J. Appl. Polym. Sci., 108, 2301 (2008).CrossRefGoogle Scholar
(19).
A. M. Al-Sabagh, M. R. Noor El-Din, R. E. Morsi, and M. Z. Elsabee, J. Pet. Sci. Eng., 65, 139 (2009).CrossRefGoogle Scholar
(20).
H. Maeda, M. Ueda, T. Morinaga, and T. Matsumoto, J. Med. Chem., 28, 455 (1985).CrossRefGoogle Scholar
(21).
E. Bacu, G. Charlotte, A. Couture, P. Grandclaudon, G. Singurel, and A. Carpov, Eur. Polym. J., 38, 1509 (2002).CrossRefGoogle Scholar
(22).
W. Fang, Y. Cai, X. Chen, R. Su, T. Chen, N. Xia, L. Li, Q. Yang, J. Han, and S. Han, Bioorg. Med. Chem. Lett., 19, 1903 (2009).CrossRefGoogle Scholar
(23).
A. Khazaei, S. Saednia, J. Saien, M. Kazem-rostami, M. Sadeghpour, M. K. Borazjani, and F. Abbasi, J. Braz. Chem. Soc., 24, 1109 (2013).Google Scholar
(24).
W. J. Cloete, L. Verwey, and B. Klumperman, Eur. Polym. J., 49, 1080 (2013).CrossRefGoogle Scholar
(25).
M. Ignatova, O. Stoilova, N. Manolova, N. Markova, and I. Rashkov, Macromol. Biosci., 10, 944 (2010).CrossRefGoogle Scholar
(26).
M. Ignatova, Z. Petkova, N. Manolova, N. Markova, and I. Rashkov, Macromol. Biosci., 12, 104 (2012).CrossRefGoogle Scholar
(27).
J. S. Patel, S. V Patel, N. P. Talpada, and H. A. Patel, Angew. Makromol. Chem., 271, 24 (1999).CrossRefGoogle Scholar
(28).
R. R. De Chimie, I. Popescu, D. M. Suflet, I. M. Pelin, and G. C. Chitanu, Rev. Roum. Chim., 56, 173 (2011).Google Scholar
(29).
A. R. Long, C. C. O’Brien, K. Malhotra, C. T. Schwall, A. D. Albert, A. Watts, and N. N. Alder, BMC Biotechnol., 13, 41 (2013).CrossRefGoogle Scholar
(30).
S. Scheidelaar, M. C. Koorengevel, J. D. Pardo, J. D. Meeldijk, E. Breukink, and J. A. Killian, Biophys. J., 108, 279 (2015).CrossRefGoogle Scholar
(31).
D. J. K. Swainsbury, S. Scheidelaar, R. Van Grondelle, J. A. Killian, and M. R. Jones, Angew. Chem. Int. Ed., 53, 11803 (2014).CrossRefGoogle Scholar
(32).
R. M. Ottenbrite, L. A. Utracki, and S. Inoue, Current Topics in Polymer Science: Rheology and Polymer Processing, Multiphase Systems, Hanser Publishers, Munich, 1987.Google Scholar
(33).
L. A. Utracki and B. D. Favis, Polymer Alloys and Blends, Marcel Dekker, New York, 1989.Google Scholar
(34).
J. Washiyama, E. J. Kramer, and C. Y. Hui, Macromolecules, 26, 2928 (1993).CrossRefGoogle Scholar
(35).
I. Insua, A. Wilkinson, and F. Fernandez-Trillo, Eur. Polym. J., 81, 198 (2016).CrossRefGoogle Scholar
(36).
J. R. Potts, D. R. Dreyer, C. W. Bielawski, and R. S. Ruoff, Polymer (Guildf), 52, 5 (2011).CrossRefGoogle Scholar
(37).
M. R. Nikpour, S. M. Rabiee, and M. Jahanshahi, Compos. Part B: Eng., 43, 1881 (2012).CrossRefGoogle Scholar
(38).
C. Demitri, A. Moscatello, A. Giuri, M. G. Raucci, and C. E. Corcione, Polymers (Basel)., 7, 2584 (2015).CrossRefGoogle Scholar
(39).
A. Samzadeh-kermani, and N. Esfandiary, Adv. Nanoparticles, 18 (2016).Google Scholar
(40).
X. Lai, C. Sun, H. Tian, W. Zhao, and L. Gao, Int. J. Pharm., 352, 66 (2008).CrossRefGoogle Scholar
(41).
V. R. Pereira, A. M. Isloor, U. K. Bhat, and A. F. Ismail, Desalination, 351, 220 (2014).CrossRefGoogle Scholar
(42).
N. A. Samoilova, M. A. Krayukhina, and I. A. Yamskov, Appl. Biochem. Microbiol., 38, 386 (2002).CrossRefGoogle Scholar
(43).
M. R. de Moura, F. A. Aouada, and L. H. C. Mattoso, J. Colloid Interface Sci., 321, 477 (2008).CrossRefGoogle Scholar
(44).
E. S. Abdou, S. S. Elkholy, M. Z. Elsabee, and M. Eweis, J. Appl. Polym. Sci., 108, 2290 (2008).CrossRefGoogle Scholar
(45).
P. F. Olurinola, J. O. Ehinmidu, and J. J. Bonire, Appl. Envir. Microbiol., 58, 758 (1992). http://aem.asm.org/cgi/content/long/58/2/758 (accessed December 27, 2015).Google Scholar
(46).
M. G. Nair, S. K. Mishra, A. R. Putnam, and R. C. Pahdey, J. Antibiot. (Tokyo)., 45, 1738 (1992).CrossRefGoogle Scholar
(47).
J. S. Park, J. H. Kim, Y. C. Nho, and O. H. Kwon, J. Appl. Polym. Sci., 69, 2213 (1998).CrossRefGoogle Scholar
(48).
G. W. Snedecor and W. G. Cochran, Statistical Methods, 6th ed., Oxford and IBH Publishing Co., New Delhi, 1967.Google Scholar
(49).
X. Jiang, L. Chen, and W. Zhong, Polymer, 54, 457 (2003).Google Scholar
(50).
M. R. Kasaai, J. Arul, and G. Charlet, J. Polym. Sci., Part B: Polym. Phys., 38, 2591 (2000).CrossRefGoogle Scholar
(51).
W. Wang, S. Bo, S. Li, and W. Qin, Int. J. Biol. Macromol., 13, 281 (1991).CrossRefGoogle Scholar
(52).
E. Ryuichi, T. Hinokuma, and M. Takeda, J. Polym. Sci., Part A-2 Polym. Phys., 6, 665 (1968).Google Scholar
Y. Chen, M. T. Guarnieri, A. I. Vasil, M. L. Vasil, C. T. Mant, and R. S. Hodges, Antimicrob. Agents Chemother., 51, 1398 (2007).CrossRefGoogle Scholar
(55).
J. J. Bonire, Niger. J. Sci., 19, 145 (1985).Google Scholar
(56).
P. F. Olurinola, J. O. Ehinmidu, and J. J. Bonire, Appl. Environ. Microbiol., 58, 758 (1992).Google Scholar