The Antimicrobial Behavior of Polyelectrolyte Chitosan-Styrene Maleic Anhydride Nano Composites

  • Eman A. Ali
  • Mohamed Eweis
  • Said Elkholy
  • Mohamed N. Ismail
  • Maher Elsabee
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Abstract

A new antimicrobial polyelectrolyte polymer was prepared based on chitosan and alternating styrene maleic anhydride (SMA) copolymer. The SMA was subjected to alkaline hydrolysis, followed by blending with chitosan and chitosan in the nano form which has been prepared by self-assembly technique with particle size 46±0.08 nm. The composition was investigated and characterized by spectral and, thermogravimetric analysis, dynamic light scattering, and transmission electron microscopy. The nano polyelectrolyte complexes and composite were screened for their antimicrobial behavior and showed excellent antifungal as well as antibacterial efficacy against four bacterial and fungal strains. The hydrolyzed styrene maleic anhydride-nano-chitosan exhibited higher antimicrobial activity than the hydrolyzed styrene maleic anhydride-chitosan.
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Keywords

styrene maleic anhydride copolymer chitosan polyelectrolyte nano-composites antimicrobial properties 
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Copyright information

© The Polymer Society of Korea and Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Eman A. Ali
    • 3
  • Mohamed Eweis
    • 2
  • Said Elkholy
    • 1
  • Mohamed N. Ismail
    • 3
  • Maher Elsabee
    • 1
  1. 1.Chemistry Department, Faculty of ScienceCairo UniversityGizaEgypt
  2. 2.Botany and Microbiology Department, Faculty of ScienceCairo UniversityGizaEgypt
  3. 3.Polymers and Pigments DepartmentNational Research CenterGizaEgypt

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