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Resource diversity of Chinese macrofungi: edible, medicinal and poisonous species

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Abstract

The huge land areas in China provide highly diverse habitats for macrofungi. Of these macrofungi, many are directly related to people’s daily life and have been utilized by ancient Chinese for at least 6800 years. In this study, we evaluate the current known resource diversity of Chinese macrofungi. A total of 1662 taxa are summarized, and all species names and their authorities have been checked and corrected according to authentic mycological databases. Among the 1662 taxa, 1020, 692, and 480 are considered to be edible, medicinal and poisonous mushrooms, respectively. A few of edible macrofungi in China are commonly used for commercial production. All known medicinal functions are labeled for medicinal species. The most common medicinal functions possessed by Chinese macrofungi are antitumor or anticancer, followed by antioxidant and antimicrobial. A total of 277 Chinese macrofungi are edible simultaneously with certain medicinal functions and without known toxicity. These species could be treated as “Gold Mushrooms”. Contrarily, 193 edible and/or medicinal species are also recognized as poisonous mushrooms. To avoid poisoning caused by these species, ingestion either in a proper way or in small amounts is important. However, the mycotoxins metabolized by these poisonous species could be a huge wealth of natural products yet to be explored. How to utilize these Chinese macrofungal resources is a critical to benefit humans worldwide.

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References

  • Acharya K, Chatterjee S, Biswas G, Chatterjee A, Saha GK (2012) Hepatoprotective effect of a wild edible mushroom on carbon tetrachloride-induced hepatotoxicity in mice. J Pharm Pharm Sci 4:285–288

    CAS  Google Scholar 

  • Adebayo EA, Oloke JK, Majolagbe ON, Ajani RA, Bora TC (2012) Antimicrobial and anti-inflammatory potential of polysaccharide from Pleurotus pulmonarius LAU 09. Afr J Microbiol Res 6:3315–3323

    CAS  Google Scholar 

  • Ahmed MS, Noor ZM, Ariffin ZZ (2013) New thrombolytic agent from endophytic fungi and Lignosus rhinocerus. Open Conf Proc J 4(Suppl. 2):95–98

    Google Scholar 

  • Aina DA, Jonathan SG, Olawuyi OJ, Ojelabi DO, Durowoju BM (2012) Antioxidant, antimicrobial and phytochemical properties of alcoholic extracts of Cantharellus cibarius—a Nigerian mushroom. N Y Sci J 5:114–120

    Google Scholar 

  • Akata I, Zengin G, Picot CMN, Mahomoodally MF (2019) Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family. S Afr J Bot 120:95–99

    Article  CAS  Google Scholar 

  • Akyuz M, Kirbag S (2009) Antimicrobial activity of Pleurotus eryngii var. ferulae grown on various agro-wastes. Eurasia J Biosci 3:58–63

    Article  Google Scholar 

  • Alam N, Yoon KN, Lee TS (2011) Antihyperlipidemic activities of Pleurotus ferulae on biochemical and histological function in hypercholesterolemic rats. J Res Med Sci 16:776–786

    PubMed  PubMed Central  Google Scholar 

  • Al-Fatimi M, Schröder G, Kreisel H, Lindequist U (2013) Biological activities of selected basidiomycetes from Yemen. Die Pharm 68:221–226

    CAS  Google Scholar 

  • Altuner EM, Akata I (2010) Antimicrobial activity of some macrofungi extracts. SAÜ. Fen Bilim Derg 14:45–49

    Google Scholar 

  • Altuner EM, Akata I, Canli K (2012) In vitro antimicrobial activity screening of Bovista nigrescens Pers. J For Fac Kast Univ 12:90–96

    Google Scholar 

  • Alves MJ, Ferreira ICFR, Martins A, Pintado M (2012) Antimicrobial activity of wild mushroom extracts against clinical isolates resistant to different antibiotics. J Appl Microbiol 113:466–475

    Article  CAS  PubMed  Google Scholar 

  • Amen YM, Zhu QC, Afifi MS, Halim AF, Ashour A, Shimizu K (2016) New cytotoxic lanostanoid triterpenes from Ganoderma lingzhi. Phytochem Lett 17:64–70

    Article  CAS  Google Scholar 

  • Amen YM, Zhu QC, Tran HB, Afifi MS, Halim AF, Ashour A, Shimizu K (2017) Partial contribution of Rho-kinase inhibition to the bioactivity of Ganoderma lingzhi and its isolated compounds: insights on discovery of natural Rho-kinase inhibitors. J Nat Med 71:380–388

    Article  CAS  PubMed  Google Scholar 

  • Angelini P, Tirillini B, Venanzoni R (2012) In vitro antifungal activity of Calocybe gambosa extracts against yeasts and filamentous fungi. Afr J Microbiol Res 6:1810–1814

    Article  Google Scholar 

  • Anonymous (1955) Shen Nong materia medica, 102-200 AD (E. Reprinted. People’s Hygiene Press, Beijing, Han)

    Google Scholar 

  • Antonyuk VO, Nemchenko II, Tymchuk IV, Danileuchenko VV, Stoika RS (2010) Studies of hemolytical and antimicrobial action of poisonous mushrooms lectins of Amanita virosa Secr. and Mycena pura /Fr./Kumm. Biopolym Cell 26:29–35

    Article  CAS  Google Scholar 

  • Aslim B, Ozturk S (2011) Phenolic composition and antimicrobial and antioxidant activities of Leucoagaricus leucothites (Vittad.) Wasser. J Med Food 14:1419–1424

    Article  CAS  PubMed  Google Scholar 

  • Athanasakis G, Aligiannis N, Gonou-Zagou Z, Skaltsounis AL, Fokialakis N (2013) Antioxidant properties of the wild edible mushroom Lactarius salmonicolor. J Med Food 16:760–764

    Article  CAS  PubMed  Google Scholar 

  • Awala SI, Oyetayo VO (2015) The phytochemical and antimicrobial properties of the extracts obtained from Trametes elegans collected from Osengere in Ibadan, Nigeria. Jordan J Biol Sci 8:289–299

    Article  CAS  Google Scholar 

  • Ayodele SM, Idoko ME (2011) Antimicrobial activities of four wild edible mushrooms in Nigeria. Int J Sci Nat 2:55–58

    Google Scholar 

  • Baggio CH, Freitas CS, Marcon R, Werner MF, Rae GA, Smiderle FR, Sassaki GL, Iacomini M, Marques MC, Santos AR (2012) Antinociception of β-d-glucan from Pleurotus pulmonarius is possibly related to protein kinase C inhibition. Int J Biol Macromol 50:872–877

    Article  CAS  PubMed  Google Scholar 

  • Bai HN, Wang ZY, Cui J, Yun KL, Zhang H, Liu RH, Fan ZL, Cheng CL (2014) Synergistic radiation protective effect of purified Auricularia auricular-judae polysaccharide (AAP IV) with grape seed procyanidins. Molecules 19:20675–20694

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Bal C, Akgul H, Sevindik M, Akata I, Yumrutas O (2017) Determination of the anti-oxidative activities of six mushrooms. Fresen Environ Bull 26:6246–6252

    CAS  Google Scholar 

  • Bala N, Aitken EAB, Cusack A, Steadman KJ (2012) Antimicrobial potential of Australian macrofungi extracts against foodborne and other pathogens. Phytother Res 26:465–469

    PubMed  Google Scholar 

  • Bao HY, Sun Q, Huang W, Sun X, Bau T, Li Y (2015) Immunological regulation of fermentation mycelia of Fomitopsis pinicola on mice. Mycosystema 34:287–292

    CAS  Google Scholar 

  • Bao Y, Ma Y, Li YS, Zhang YQ, Wu Y, Liu CL (2016) Structure identification and free radical scavenging activity of polysaccharide from fruit bodies of Leucopaxillus giganteus. Food Sci 37:71–76

    CAS  Google Scholar 

  • Bao HY, Li ZJ, Yang SD, Ma WC, Bai L, Wang XB, Bau T, Li Y (2019) Photosensitive toxic component of Bulgaria inquinans. Mycosystema 38:117–126

    Google Scholar 

  • Bau T, Bao HY, Li Y (2014) A revised checklist of poisonous mushrooms in China. Mycosystema 33:517–548

    Google Scholar 

  • Beara IN, Lesjak MM, Cetojević-Simin DD, Marjanović ZS, Ristić JD, Mrkonjić ZO, Mimica-Dukić NM (2014) Phenolic profile, antioxidant, anti-inflammatory and cytotoxic activities of black (Tuber aestivum Vittad.) and white (Tuber magnatum Pico) truffles. Food Chem 165:460–466

    Article  CAS  PubMed  Google Scholar 

  • Benarous K, Bombarda I, Iriepa I, Moraleda I, Gaetan H, Linani A, Tahri D, Sebaa M, Yousfi M (2015) Harmaline and hispidin from Peganum harmala and Inonotus hispidus with binding affinity to Candida rugosa lipase: In silico and in vitro studies. Bioorg Chem 62:1–7

    Article  CAS  PubMed  Google Scholar 

  • Berek I, Becker A, Schrödera H, Härtl A, Höllt V, Grecksch G (2009) Ampullosporin A, a peptaibol from Sepedonium ampullosporum HKI-0053 with neuroleptic-like activity. Behav Brain Res 203:232–239

    Article  CAS  PubMed  Google Scholar 

  • Bhunia SK, Dey B, Maity KK, Patra S, Mandal S, Maiti S, Maiti TK, Sikdar SR, Islam SS (2010) Structural characterization of an immunoenhancing heteroglycan isolated from an aqueous extract of an edible mushroom, Lentinus squarrosulus (Mont.) Singer. Carbohydr Res 345:2542–2549

    Article  CAS  PubMed  Google Scholar 

  • Bi HT, Han H, Li ZH, Ni WH, Chen Y, Zhu JJ, Gao TT, Hao M, Zhou YF (2011) A water-soluble polysaccharide from the fruit bodies of Bulgaria inquinans (Fries) and its anti-malarial activity. Evid Based Compl Alt. https://doi.org/10.1093/ecam/neq070

    Article  Google Scholar 

  • Bi HT, Gao TT, Li ZH, Ji L, Yang W, Iteku BJ, Liu EX, Zhou YF (2013a) Structural elucidation and antioxidant activity of a water-soluble polysaccharide from the fruit bodies of Bulgaria inquinans (Fries). Food Chem 138:1470–1475

    Article  CAS  PubMed  Google Scholar 

  • Bi HT, Gao TT, Liu DB, Tai GH, Wei M, Zhou YF (2013b) Structures of (1 → 6)-β-d-glucans from Bulgaria inquinans (Fries) and their immunological activities. Carbohydr Polym 93:547–552

    Article  CAS  PubMed  Google Scholar 

  • Biswas G, Sarkar S, Acharya K (2010) Free radical scavenging and anti-inflammatory activities of the extracts of Astraeus hygrometricus (Pers.) Morg. Lat Am J Pharm 29:549–553

    Google Scholar 

  • Biswas G, Sarkar S, Acharya K (2011) Hepatoprotective activity of the ethanolic extract of Astraeus hygrometricus (Pers.) Morg. Dig J Nanomater Bios 6:637–641

    Google Scholar 

  • Borges GM, De Barba FFM, Schiebelbein AP, Pereira BP, Chaves MB, Silveira MLL, Pinho MSL, Furlan SA, Wisbeck E (2014) Extracellular polysaccharide production by a strain of Pleurotus djamor isolated in the south of Brazil and antitumor activity on Sarcoma 180. Braz J Microbiol 44:1059–1065

    Article  PubMed  PubMed Central  Google Scholar 

  • Bunbamrung N, Intaraudom C, Dramae A, Boonyuen N, Veeranondha S, Rachtawee P, Pittayakhajonwut P (2017) Antimicrobial activity of illudalane and alliacane sesquiterpenes from the mushroom Gloeostereum incarnatum BCC41461. Phytochem Lett 20:274–281

    Article  CAS  Google Scholar 

  • Butkhup L, Samappito W, Jorjong S (2018) Evaluation of bioactivities and phenolic contents of wild edible mushrooms from northeastern Thailand. Food Sci BioTechnol 27:193–202

    Article  CAS  PubMed  Google Scholar 

  • Byeon SE, Lee J, Lee E, Lee SY, Hong EK, Kim YE, Cho JY (2009) Functional activation of macrophages, monocytes and splenic lymphocytes by polysaccharide fraction from Tricholoma matsutake. Arch Pharm Res 32:1565–1572

    Article  CAS  PubMed  Google Scholar 

  • Cai Q, Cui YY, Yang ZL (2016) Lethal Amanita species in China. Mycologia 108:993–1009

    Article  CAS  PubMed  Google Scholar 

  • Cai Q, Chen ZH, He ZM, Luo H, Yang ZL (2018) Lepiota venenata, a new species related to toxic mushroom in China. J Fungal Res 16:63–69

    Google Scholar 

  • Cao Y, Yuan HS (2013) Ganoderma mutabilis sp. nov. from southwestern China based on morphological and molecular data. Mycol Prog 12:121–126

    Article  Google Scholar 

  • Cao Y, Wu SH, Dai YC (2012) Species clarification of the prize medicinal Ganoderma mushroom “Lingzhi”. Fungal Divers 56:49–62

    Article  Google Scholar 

  • Cao CL, Han ML, Cui BK, Yu HY (2013) Antioxidant activities of different fractional extracts from fruiting bodies of three Phellinus species. Mycosystema 32:883–890

    Google Scholar 

  • Cao J, Zhang HJ, Xu CP (2014) Culture characterization of exopolysaccharides with antioxidant activity produced by Pycnoporus sanguineus in stirred-tank and airlift reactors. J Taiwan Inst Chem E 45:2075–2080

    Article  CAS  Google Scholar 

  • Cao YC, Bao HY, Li X, Bau T, Li Y (2017) Anti-tumor activities of Auricularia cornea fruiting body extract in H22 bearing mice. Mycosystema 36:1289–1298

    Google Scholar 

  • Castillo TA, Pereira JRG, Alves JMA, Teixeira MFS (2017) Mycelial growth and antimicrobial activity of species of genus Lentinus (Agaricomycetes) from Brazil. Int J Med Mushrooms 19:1135–1143

    Article  PubMed  Google Scholar 

  • Cen WY, Yu XN, Huang WJ, Zhu F, Chu CF (2016) Chemical components and antioxidant activity of essential oil from Earliella scabrosa (Pers.) Gilb. & Ryarden. Guangxi Agric Sci 47:2129–2133

    Google Scholar 

  • Chakraborty P, Thangaraman V, Thangamani S, Ravi D, Abraham J (2016) Bioactivity of Hypomyces chrysospermus methanol extract. Res J Pharm Technol 9:157–161

    Article  Google Scholar 

  • Chan PM, Kanagasabapathy G, Tan YS, Sabaratnam V, Kuppusamy UR (2013) Amauroderma rugosum (Blume & T. Nees) Torrend: nutritional composition and antioxidant and potential anti-inflammatory properties. Evid Based Compl Alt. https://doi.org/10.1155/2013/304713

    Article  Google Scholar 

  • Chan PM, Tan YS, Chua KH, Sabaratnam V, Kuppusamy UR (2015) Attenuation of inflammatory mediators (TNF-α and nitric oxide) and up-regulation of IL-10 by wild and domesticated basidiocarps of Amauroderma rugosum (Blume & T. Nees) Torrend in LPS-stimulated RAW264.7 cells. PloS ONE 10:e0139593

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Chandrasekaran G, Lee YC, Park H, Wu YZ, Shin HJ (2016) Antibacterial and antifungal activities of lectin extracted from fruiting bodies of the Korean cauliflower medicinal mushroom, Sparassis latifolia (Agaricomycetes). Int J Med Mushrooms 18:291–299

    Article  PubMed  Google Scholar 

  • Chang GY (2015) Optimization of the extraction process of polysaccharide from Gloeostereum incarnatum by response surface methodology. Food Res Dev 36:16–20

    Google Scholar 

  • Chang CJ, Lu CC, Lin CS, Martel J, Ko YF, Ojcius DM, Wu TR, Tsai YH, Yeh TS, Lu JJ, Lai HC, Young JD (2018) Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. Int J Obesity 42:231–243

    Article  Google Scholar 

  • Chatterjee A, Khatua S, Chatterjee S, Mukherjee S, Mukherjee A, Paloi S, Acharya K, Bandyopadhyay SK (2013) Polysaccharide-rich fraction of Termitomyces eurhizus accelerate healing of indomethacin induced gastric ulcer in mice. Glycoconj J 30:759–768

    Article  CAS  PubMed  Google Scholar 

  • Chen B (2010) Optimization of extraction of Tremella fuciformis polysaccharides and its antioxidant and antitumour activities in vitro. Carbohydr Polym 81:420–424

    Article  CAS  Google Scholar 

  • Chen JY (2015) Study on effect of carboxymethyl-pachymaran on anti-hepatitis virus in vivo and in vitro. Chin J Biochem Pharm 35:66–70

    Google Scholar 

  • Chen YY, Cui BK (2015) Phylogenetic analysis and taxonomy of the Antrodia heteromorpha complex in China. Mycoscience 57:1–10

    Article  CAS  Google Scholar 

  • Chen H, Cui BK (2017) Multi-locus phylogeny and morphology reveal five new species of Fomitiporia (Hymenochaetaceae) from China. Mycol Prog 16:687–701

    Article  Google Scholar 

  • Chen Y, Sun H, Zhang SB, Wang LA (2009) Antioxidant and anti-tumor activities of extracts from Lepista irina. Food Sci 30:214–217

    CAS  Google Scholar 

  • Chen JN, Ma CY, Tsai PF, Wang YT, Wu JSB (2010a) In vitro antitumor and immunomodulatory effects of the protein PCP-3A from mushroom Pleurotus citrinopileatus. J Agric Food Chem 58:12117–12122

    Article  CAS  PubMed  Google Scholar 

  • Chen XH, Xia LX, Zhou HB, Qiu GZ (2010b) Chemical composition and antioxidant activities of Russula griseocarnosa sp. nov. J Agric Food Chem 58:6966–6971

    Article  CAS  PubMed  Google Scholar 

  • Chen YC, Ho HL, Su CH, Sheu MT (2010c) Anticancer effects of Taiwanofungus camphoratus extracts, isolated compounds and its combinational use. J Exper Clin Med 2:274–281

    Article  Google Scholar 

  • Chen YY, Gu XH, Huang SQ, Li JW, Wang X, Tang J (2010d) Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and evaluation of its anti-tumor activities. Int J Biol Macromol 46:429–435

    Article  CAS  PubMed  Google Scholar 

  • Chen J, Zhang LZ, Wei D, Xu XF (2011a) Composition and antitumor activity of polysaccharides from Sarcodon imbricatus. J S China Univ Technol (Nat Sci Ed) 39:110–114

    Google Scholar 

  • Chen JN, de Mejia EG, Wu JSB (2011b) Inhibitory effect of a glycoprotein isolated from golden oyster mushroom (Pleurotus citrinopileatus) on the lipopolysaccharide-induced inflammatory reaction in RAW 264.7 macrophage. J Agric Food Chem 59:7092–7097

    Article  CAS  PubMed  Google Scholar 

  • Chen XL, Li TH, Shen YH (2011c) In vitro antioxidative and antitumor activities of fermentions of Lepista sordida (Schumach.:Fr.) Singer. J Anhui Agric Sci 39:8276–8278

    Google Scholar 

  • Chen GT, Ma XM, Liu ST, Liao YL, Zhao GQ (2012a) Isolation, purification and antioxidant activities of polysaccharides from Grifola frondosa. Carbohydr Polym 89:61–66

    Article  CAS  PubMed  Google Scholar 

  • Chen JJ, Mao D, Yong YY, Li JL, Wei H, Lu L (2012b) Hepatoprotective and hypolipidemic effects of water-soluble polysaccharidic extract of Pleurotus eryngii. Food Chem 130:687–694

    Article  CAS  Google Scholar 

  • Chen SM, Lu C, Gu HB, Mehta A, Li JW, Romano PB, Horn D, Hooper DC, Bazemore-Walker CR, Block T (2012c) Aleuria Aurantia Lectin (AAL)-reactive immunoglobulin G rapidly appears in sera of animals following antigen exposure. PloS ONE 7:e44422

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chen Y, Hu ML, Wang C, Yang YL, Chen JH, Ding JN, Guo WQ (2013) Characterization and in vitro antitumor activity of polysaccharides from the mycelium of Sarcodon aspratus. Int J Biol Macromol 52:52–58

    Article  CAS  PubMed  Google Scholar 

  • Chen ZH, Zhang P, Zhang ZG (2014) Investigation and analysis of 102 mushroom poisoning cases in Southern China from 1994 to 2012. Fungal Divers 64:123–131

    Article  Google Scholar 

  • Chen YI, Tzeng CY, Cheng YW, Hsu TH, Ho WJ, Liang ZC, Hsieh CW, Tzen JTC, Chang SL (2015a) The involvement of serotonin in the hypoglycemic effects produced by administration of the aqueous extract of Xylaria nigripes with steroid-induced insulin-resistant rats. Phytother Res 29:770–776

    Article  CAS  PubMed  Google Scholar 

  • Chen YJ, Sun JC, Zhang XQ, Du SM, Zhao P, Zhang YZ (2015b) Effects of N 6-(2-hydroxyethyl) adenosine in Cordyceps militaris on the hypnotic of mice. Chin J New Drug 24:813–817

    CAS  Google Scholar 

  • Chen GJ, Zhang SQ, Ran CX, Wang LS, Kan JQ (2016a) Extraction, characterization and antioxidant activity of water-soluble polysaccharides from Tuber huidongense. Int J Biol Macromol 91:431–442

    Article  CAS  PubMed  Google Scholar 

  • Chen H, Zhou JL, Cui BK (2016b) Two new species of Fomitiporia (Hymenochaetales, Basidiomycota) from Tibet, southwest China. Mycologia 108:1010–1017

    Article  CAS  PubMed  Google Scholar 

  • Chen HP, Zhao ZZ, Zhang Y, Bai X, Zhang L, Liu JK (2016c) (+)- and (−)-ganodilactone, a pair of meroterpenoid dimers with pancreatic lipase inhibitory activities from the macromycete Ganoderma leucocontextum. RSC Adv 6:64469–64473

    Article  CAS  Google Scholar 

  • Chen YX, Zhang K, Gong SZ (2017a) Tyrosinase activity inhibition kinetics and skin irritation of Poria cocos extract. China Surfactant Deterg Cosmet 47:317–321

    Google Scholar 

  • Chen Y, Du XJ, Zhang Y, Liu XH, Wang XD (2017b) Ultrasound extraction optimization, structural features, and antioxidant activity of polysaccharides from Tricholoma matsutake. J Zhejiang Univ Sci B (Biomed Biotechnol) 18:674–684

    Article  CAS  Google Scholar 

  • Chen P, Yan J, Liang L, Liu W, Gou XJ, He G (2019) Degradation, phosphate modification and antioxidant activity of Tremella fuciformis polysaccharide. Sci Technol Food Ind 40(9):34–37

    Google Scholar 

  • Cheng XY, Bao HY, Ding Y, Kim YH (2011) Free radical scavenging activities of phenolic and flavonoid compounds from fruiting body of Phellinus vaninii. Mycosystema 30:281–287

    CAS  Google Scholar 

  • Cheng HY, Chang DR, Feng CP, Chang MC, Wang J, Li HJ, Li Y (2012) Effects of Agaricus blazei polysaccharides on the mRNA expression of cytokines in lead-poisoning rats. Mycosystema 31:258–266

    CAS  Google Scholar 

  • Cheng SJ, Eliaz I, Lin JF, Sliva D (2013) Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7. Int J Oncol 42:1869–1874

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Cheng LJ, Xie XR, Yang M, Liu F, Lian XJ, Jiang FR (2017a) Study on effects of Ganoderma lucidum extract on immunity of mice organism. J Chengdu Univ (Nat Sci Ed) 36:361–363

    Google Scholar 

  • Cheng P, Geng Y, Xu HY, Lu ZM, Shi JS, Xu ZH (2017b) Isolation and anti-inflammatory activity of n-hexane extract from Armillaria mellea. Nat Prod Res Dev 29:1523–1528

    Google Scholar 

  • Chien RC, Tsai SY, Lai EI, Mau JL (2015) Antiproliferative activities of hot water extracts from culinary-medicinal mushrooms, Ganoderma tsugae and Agrocybe cylindracea (higher basidiomycetes) on cancer cells. Int J Med Mushrooms 17:453–462

    Article  PubMed  Google Scholar 

  • Chirinang P, Intarapichet KO (2009) Amino acids and antioxidant properties of the oyster mushrooms, Pleurotus ostreatus and Pleurotus sajor-caju. Scienceasia 35:326–331

    Article  CAS  Google Scholar 

  • Chittaragi A, Naika R (2014) Antifungal properties of Hygrocybe cantharellus (schwein.) Murrill. Int J Biol Pharm Res 5:581–589

    Google Scholar 

  • Chittaragi A, Naika R, Ashwani HS, Nagaraj K (2013) Antibacterial potential of Geastrum triplex Jungh. against plant and human pathogens. Int J PharmTechnol Res 5:1456–1464

    Google Scholar 

  • Choi HN, Jang YH, Kim MJ, Seo MJ, Kang BW, Jeong YK, Kim JI (2014a) Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice. Nutr Res Pract 8:172–176

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Choi MH, Han HK, Lee YJ, Jo HG, Shin HJ (2014b) In vitro anti-cancer activity of hydrophobic fractions of Sparassis latifolia extract using AGS, A529, and HepG2 cell lines. J Mushroom 12:304–310

    Article  Google Scholar 

  • Choi MH, Wu YZ, Oh DS, Kim SK, Shin HJ (2016) Antioxidant and antidiabetic activities of mycelial and fruit-body extracts from Mycoleptodonoides aitchisonii. Biotechnol Bioproc E 21:355–363

    Article  CAS  Google Scholar 

  • Chong EL, Sia CM, Chang SK, Yim HS, Khoo HE (2014) Antioxidative properties of an extract of Hygrocybe conica, a wild edible mushroom. Malays J Nutr 20:101–111

    Google Scholar 

  • Ćilerdžić J, Stajić M, Vukojević J, Milovanović I, Muzgonja N (2015) Antioxidant and antifungal potential of Pleurotus ostreatus and Agrocybe cylindracea basidiocarps and mycelia. Curr Pharm Biotechnol 16:179–186

    Article  PubMed  CAS  Google Scholar 

  • Ćilerdžić JL, Stajić MM, Milovanović IN, Galić MM, Vukojević JB (2017) Antioxidative potential of Daedaleopsis tricolor basidiocarps and mycelium. Matica Srpska J Nat Sci 132:19–27

    Article  Google Scholar 

  • Cui DJ (2009) Cordyceps pruinosa for the treatment of inflammatory bowel disease. Iran J Med Hypoth Ideas 3:23

    Google Scholar 

  • Cui BK, Dai YC (2012) Wood-decaying fungi in eastern Himalayas 3. Polyporus from Laojunshan Mountains, Yunnan Province. Mycosystema 31:486–492

    Google Scholar 

  • Cui BK, Tang LP, Dai YC (2011) Morphological and molecular evidences for a new species of Lignosus (Polyporales, Basidiomycota) from tropical China. Mycol Prog 10:267–271

    Article  Google Scholar 

  • Cui LX, Zhang Y, Zheng Y (2013) Optimization of extraction and antioxidant activities of polysaccharides from Sparassis crispa. Food Ind 34(6):24–28

    CAS  Google Scholar 

  • Cui YY, Feng B, Wu G, Xu JP, Yang ZL (2016) Porcini mushrooms (Boletus sect. Boletus) from China. Fungal Divers 81:189–212

    Article  Google Scholar 

  • Cui YY, Cai Q, Tang LP, Liu JW, Yang ZL (2018) The family Amanitaceae: molecular phylogeny, higher-rank taxonomy and the species in China. Fungal Divers 91:5–230

    Article  Google Scholar 

  • Dai YC (2010) Hymenochaetaceae (Basidiomycota) in China. Fungal Divers 45:131–343

    Article  Google Scholar 

  • Dai YC, Xiong HX (2008) Irpex (Basidiomycota, Steccherinaceae) in China. Mycosystema 27:515–519

    Google Scholar 

  • Dai YC, Yang ZL, Cui BK, Yu CJ, Zhou LW (2009) Species diversity and utilization of medicinal mushrooms and fungi in China (Review). Int J Med Mushrooms 11:287–302

    Article  Google Scholar 

  • Dai YC, Zhou LW, Yang ZL, Wen HA, Bau T, Li TH (2010) A revised checklist of edible fungi in China. Mycosystema 29:1–21

    Google Scholar 

  • Dai SJ, Vlasák J, Tomšovský M, Wu F (2017) Porodaedalea chinensis (Hymenochaetaceae, Basidiomycota)—a new polypore from China. Mycosphere 8:986–993

    Article  Google Scholar 

  • Deng G, Lin H, Seidman A, Fornier M, D’Andrea G, Wesa K, Yeung S, Cunningham-Rundles S, Vickers AJ, Cassileth B (2009) A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects. J Cancer Res Clin 135:1215–1221

    Article  CAS  Google Scholar 

  • Deng C, Hu Z, Fu HT, Hu MH, Xu X, Chen JH (2012) Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata. Int J Biol Macromol 51:70–75

    Article  CAS  PubMed  Google Scholar 

  • Deng C, Fu HT, Teng LP, Hu Z, Xu XF, Chen JH, Ren TL (2013) Anti-tumor activity of the regenerated triple-helical polysaccharide from Dictyophora indusiata. Int J Biol Macromol 61:453–458

    Article  CAS  PubMed  Google Scholar 

  • Deng XB, Zhou X, Zhang N, Li AX, Wang SM (2015) Research on Pleurotus spodoleucas zymotic fluid’s capability of preventing mice’s hyperlipidemia, liver protection and antioxidation. Edible Fungi China 34:37–40

    Google Scholar 

  • Deng C, Fu HT, Shang JY, Qiao ZQ, Zhao C, Chen JH (2017) Preparation, chemical analysis and biological activity of polysaccharides from fermented Tremella aurantialba. J Food Sci Biotechnol 36:67–73

    Google Scholar 

  • Dharmaraj K, Kuberan T, Mahalakshmi R (2014) Comparison of nutrient contents and antimicrobial properties of Pleurotus djamor, Agaricus bisporus and Ganoderma tsugae. Int J Curr Microbiol Appl Sci 3:518–526

    Google Scholar 

  • Dimitrijevic M, Jovanovic VS, Cvetkovic J, Mihajilov-Krstev T, Stojanovic G, Mitic V (2015) Screening of antioxidant, antimicrobial and antiradical activities of twelve selected Serbian wild mushrooms. Anal Methods-UK 7:4181–4191

    Article  CAS  Google Scholar 

  • Ding X, Hou YL, Hou WR (2012) Structure feature and antitumor activity of a novel polysaccharide isolated from Lactarius deliciosus Gray. Carbohydr Polym 89:397–402

    Article  CAS  PubMed  Google Scholar 

  • Ding X, Hou YL, Qin H, Qv W (2015a) On extraction, purification and antioxidant activity of polysaccharide from Sarcodon imbricatum (L.:Fr.) Karst. J Southwest China Normal Univ (Nat Sci Ed) 40:37–42

    CAS  Google Scholar 

  • Ding X, Hou YL, Zhu YX, Wang PP, Fu L, Zhu HQ, Zhang N, Qin H, Qu W, Wang F, Hou WR (2015b) Structure elucidation, anticancer and antioxidant activities of a novel polysaccharide from Gomphus clavatus Gray. Oncol Rep 33:3162–3170

    Article  CAS  PubMed  Google Scholar 

  • Dogan HH, Aydin S (2013) Some biological activities of Lactarius vellereus (Fr.) Fr. in Turkey. Pakistan J Biol Sci 16:1279–1286

    Article  Google Scholar 

  • Dong LJ, Wang Q (2017) Research on chemical constituents and pharmacological activities of Pleurotus pulmonarius. J Fungal Res 15:208–212

    Google Scholar 

  • Dong M, Chen SP, Kita K, Ichimura Y, Guo WZ, Lu S, Sugaya S, Hiwasa T, Takiguchi M, Mori N, Kashima A, Morimura K, Hirota M, Suzuki N (2009) Anti-proliferative and apoptosis-inducible activity of sarcodonin G from Sarcodon scabrosus in HeLa cells. Int J Oncol 34:201–207

    CAS  PubMed  Google Scholar 

  • Dong XY, Lv QT, Zhang GY, Ling JY, Zhang CK (2011) Determination of the antioxidant capacity of Cordyceps Kyushuensis with DPPH assay in vitro. Chin J Exipe Trad Med Form 17:70–73

    CAS  Google Scholar 

  • Dong HJ, Wu PP, Yan RY, Xu QH, Li H, Zhang FB, Li JR, Yang B (2015) Enrichment and separation of antitumor triterpene acids from the epidermis of Poria cocos by pH-zone-refining counter-current chromatography and conventional high-speed counter-current chromatography. J Sep Sci 38:1977–1982

    Article  CAS  PubMed  Google Scholar 

  • Dong F, Yan SF, Gao CL, Chen J (2017) Structural analysis and antioxidation activity of polysaccharide RBP-I from Ramaria botrytoides. Sci Technol Food Ind 38:124–128

    Google Scholar 

  • Du XJ, Zhang JS, Yang Y, Tang QJ, Jia W, Pan YJ (2010) Purification, chemical modification and immunostimulating activity of polysaccharides from Tremella aurantialba fruit bodies. J Zhejiang Univ Sci B 11:437–442

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Du T, Wang Y, Jing J, Zhao YL, Wei XY (2017) Hepatoprotective effects of Pleurotus ferulae polysaccharide on carbon tetrachloride-induced acute hepatic injury in mice. J Shenyang Pharm Univ 34:250–253

    Google Scholar 

  • Dulay RMR, Flores KS, Tiniola RC, Marquez DHH, Cruz AGD, Kalaw SP, Reyes RG (2015) Mycelial biomass production and antioxidant activity of Lentinus tigrinus and Lentinus sajor-caju in indigenous liquid culture. Mycosphere 6:659–666

    Article  Google Scholar 

  • Dyakov MY, Kamzolkina OV, Shtaer OV, Bis’ko NA, Poedinok NL, Mikhailova OB, Tikhonova OV, Tolstikhina TE, Vasil’eva BF, Efremenkova OV (2011) Morphological characteristics of natural strains of certain species of Basidiomycetes and biological analysis of antimicrobial activity under submerged cultural conditions. Microbiology 80:274–285

    Article  CAS  Google Scholar 

  • Ebrahimzadeh MA, Nabavi SM, Nabavi SF, Eslami S (2010) Antioxidant and free radical scavenging activities of culinary-medicinal mushrooms, golden chanterelle Cantharellus cibarius and angel’s wings Pleurotus porrigens. Int J Med Mushrooms 12:265–272

    Article  Google Scholar 

  • Eguchi F, Dulay RMR, Kalaw SP, Yoshimoto H, Miyazawa N, Seyama T, Reyes R (2014) Antihypertensive activities of a Philippine wild edible white rot fungus (Lentinus sajor-caju) in spontaneously hypertensive rats as models. Adv Environ Biol 8:74–81

    Google Scholar 

  • Egwin EC, Elem RC, Egwuche RU (2011) Proximate composition, phytochemical screening and antioxidant activity of ten selected wild edible Nigerian mushrooms. Am J Food Nutr 1:89–94

    Article  Google Scholar 

  • Eik LF, Naidu M, David P, Wong KH, Tan YS, Sabaratnam V (2012) Lignosus rhinocerus (Cooke) Ryvarden: a medicinal mushroom that stimulates neurite outgrowth in PC-12 cells. Evid Based Compl Alt. https://doi.org/10.1155/2012/320308

    Article  Google Scholar 

  • Ekin S, Uzun Y, Demirel K, Bayramoglu M, Kiziltas H (2015) Chemical composition and antioxidant activity of two wild edible mushrooms from Turkey. Int J Med Mushrooms 17:1179–1188

    Article  PubMed  Google Scholar 

  • Endo M, Beppu H, Akiyama H, Wakamatsu K, Ito S, Kawamoto Y, Shimpo K, Sumiya T, Koike T, Matsui T (2010) Agaritine purified from Agaricus blazei Murrill exerts anti-tumor activity against leukemic cells. Biochem Biophy Acta 1800:669–673

    Article  CAS  Google Scholar 

  • Endo N, Fangfuk W, Kodaira M, Sakuma D, Hadano E, Hadano A, Murakami Y, Phosri C, Matsushita N, Fukuda M, Yamada A (2017) Reevaluation of Japanese Amanita section Caesareae species with yellow and brown pileus with descriptions of Amanita kitamagotake and A. chatamagotake spp. nov. Mycoscience 58:457–471

    Article  Google Scholar 

  • Engels B, Heinig U, Grothe T, Stadler M, Jennewein S (2011) Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. J Biol Chem 286:6871–6878

    Article  CAS  PubMed  Google Scholar 

  • Fan XD, Chen YH, Chang J, Chen J (2014) Structure and antitumor activity of water-soluble polysaccharide from Craterellus cornucopioides. Mod Food Sci Technol 30:50–54

    CAS  Google Scholar 

  • Fan MC, Li WX, Hu XL, Sun YN, Yu G (2017) Effect of Pleurotus eryngii different extracts on immunity activity of mice macrophages. J Food Sci Biotechnol 36:1210–1217

    Google Scholar 

  • Fatmawati S, Kondo R, Shimizu K (2013) Structure–activity relationships of lanostane-type triterpenoids from Ganoderma lingzhi as a-glucosidase inhibitors. Bioorg Med Chem Lett 23:5900–5903

    Article  CAS  PubMed  Google Scholar 

  • Feleke HT, Doshi A (2017) Antimicrobial activity and bioactive compounds of Indian wild mushrooms. Indian J Nat Prod Res 8:254–262

    CAS  Google Scholar 

  • Feng Y, Peng YM, Lu WH, He LL, Zhu F (2011) Studies on antibacterial activities of the crude extracts of the Basidiomycete Craterellus aureus (Cantharellaceae) by disk diffusion method. J Foshan Univ (Nat Sci Ed) 4:52–54

    Google Scholar 

  • Feng HQ, Sun T, Jia DM, Mu JF, Zhang YM (2013a) Study on chemical constituents and antimicrobial activity of extracts from fruit bodies of Bulgaria inquinans Fr. Mod Agric Sci Technol 10:153–154

    Google Scholar 

  • Feng W, Wu Y, You Y, Yao K, He XS (2013b) The study of Scorias spongiosa on the enzymes activity and the antioxidant activity of polysaccharide. Food Fermen Technol 49:34–37

    CAS  Google Scholar 

  • Feng T, Wang WH, Zhang JS, Fan H, Jia W, Bao HY (2016) Effects of Flammulina velutipes different extracts on tumor cells. Mycosystema 35:1234–1243

    Google Scholar 

  • Fernandes Â, Petrović J, Stojković D, Barros L, Glamočlija J, Soković M, Martins A, Ferreira ICFR (2016) Polyporus squamosus (Huds.) Fr from different origins: chemical characterization, screening of the bioactive properties and specific antimicrobial effects against Pseudomonas aeruginosa. LWT Food Sci Technol 69:91–97

    Article  CAS  Google Scholar 

  • Fernando MDM, Wijesundera RLC, Soysa SSBDP, de Silva ED, Nanayakkara CM (2016) Antioxidant potential and content of the polyphenolic secondary metabolites of white rot macrofungi; Flavodon flavus (Klotzsch.) and Xylaria feejeensis (Berk.). SDRP J Plant Sci 1:1–6

    Google Scholar 

  • Figueira MS, Sá LA, Vasconcelos AS, Moreira DR, Laurindo PS, Ribeiro DR, Santos RS, Guzzo P, Dolabela MF, Percaria S (2014) Nutritional supplementation with the mushroom Agaricus sylvaticus reduces oxidative stress in children with HIV. Can J Infect Dis Med 25:257–264

    Article  Google Scholar 

  • Froufe HJC, Abreu RMV, Ferreira ICFR (2009) A QCAR model for predicting antioxidant activity of wild mushrooms. J SAR QSAR Environ Res 20:579–590

    Article  CAS  Google Scholar 

  • Fu ZY, Wang JB, Aisa H (2016) Determination of chemical composition and antioxidant properties of a novel wild edible mushroom. Toxico Environ Chem 98:439–449

    Article  CAS  Google Scholar 

  • Gan D, Ma LP, Jiang CX, Xu RJ, Zeng XX (2011) Production, preliminary characterization and antitumor activity in vitro of polysaccharides from the mycelium of Pholiota dinghuensis Bi. Carbohydr Polym 84:997–1003

    Article  CAS  Google Scholar 

  • Gan N, Xu HL, Wu XY, Yin H, Huang YS, Ning CG (2018) Auricularia auricula-judae polysaccharide AAP-10 and its immunoregulatory activity on immunosuppressed mice. Food Sci 39:196–200

    Google Scholar 

  • Gao HL, Lei LS, Yu CL, Zhu ZG, Chen NN, Wu SG (2009) Immunomodulatory effects of Fomes fomentarius polysaccharides: an experimental study in mice. J South Med Univ 29:458–461

    CAS  Google Scholar 

  • Gao MY, Zheng LY, Yu MY, Wei W, Luo X, Wang SK (2011) Effect of Morchella conica mycelial water extract on experimental gastric ulcer. Mycosystema 30:325–330

    Google Scholar 

  • Gao WB, Zhang YM, Song XZ, Tian Y, Cheng H, Bao HY (2012) Study on the antimicrobial activity of extracts from fruit bodies of Hygrophorus lucorum Kalchbr and chemical constituents of petroleum ether part. Edible Fungi China 31:35–38

    Google Scholar 

  • Gao C, Luo J, Liu X, Ma L, Yuan XH (2016a) Recent advances in the studies of chemical compositions and bioactivities of the genus Xylaria. Mycosystema 35:767–781

    CAS  Google Scholar 

  • Gao HJ, Liu ZF, Xi YL, Zhang FQ, Zhao C, Wei SL (2016b) Effect of seleniumon crude exopolysaccharide of Lyophyllum decastes and optimization of cultivation condition. Nat Prod Res Dev 28:1965–1970

    Google Scholar 

  • Gao XY, Xia JL, Bao HY, Bau T, Li Y (2017) Antitumor activities of fruiting body extract of Funalia trogii in H22 bearing mice. Mycosystema 36:1278–1288

    Google Scholar 

  • Gaur T, Rao PB (2016) Antioxidant potential of the giant mushroom, Macrocybe gigantea (Agaricomycetes), from India in different drying methods. Int J Med Mushrooms 18:133–140

    Article  PubMed  Google Scholar 

  • Ge XJ, Zhou DJ, Wang B, Chen Y (2017) Optimization of neutroproteinase-assistant extraction of polysaccharide from the stroma of Shiraia bambusicola Henn by response surface analysis and characterization of the extracted polysaccharide. Food Sci 38:193–199

    Google Scholar 

  • Ge WJ, Zhao Y, Bau T, Li W, Gao YG, Zhu HY, Li Y, Bao HY (2018) Antitumor effect of acid-soluble polysaccharides from Trametes versicolor (L.) Lloyd in H22 tumor-bearing mice. J Northwest Agric For Univ (Nat Sci Ed) 46:8–14

    Google Scholar 

  • Geng XR, Tian GT, Zhang WW, Zhao YC, Zhao LY, Wang HX, Ng TB (2016) A Tricholoma matsutake Peptide with angiotensin converting enzyme inhibitory and antioxidative activities and antihypertensive effects in spontaneously hypertensive rats. Sci Rep UK 6:24130

    Article  CAS  Google Scholar 

  • Giri S, Biswas G, Pradhan P, Mandal SC, Acharya K (2012) Antimicrobial activities of basidiocarps of wild edible mushrooms of West Bengal, India. Int J PharmTechnol Res 4:1554–1560

    Google Scholar 

  • Gong M, Piraino F, Yan N, Zhang J, Xia M, Ma J, Cheng J, Liu X (2009) Purification, partial characterization and molecular cloning of the novel antiviral protein RC28. Peptides 30:654–659

    Article  CAS  PubMed  Google Scholar 

  • Gong SL, Xu ZL, Zhang HJ, Shan WX, Zhao C, Yan TH, Wang SM (2017) Treatment and mechanism of Lycoperdon pedicellatus Peck. on cigarette-induced chronic obstructive pulmonary disease in mice. J Pharm Res 36:435–438

    Google Scholar 

  • Greeshma P, Ravikumar KS, Neethu MN, Pandey M, Zuhara KF, Janardhanan KK (2016) Antioxidant, anti-inflammatory, and antitumor activities of cultured mycelia and fruiting bodies of the elm oyster mushroom, Hypsizygus ulmarius (Agaricomycetes). Int J Med Mushrooms 18:235–244

    Article  PubMed  Google Scholar 

  • Grzywacz A, Argasinska JG, Kala K, Opoka W, Muszynska B (2016) Anti-inflammatory activity of biomass extracts of the bay mushroom, Imleria badia (Agaricomycetes), in RAW 264.7 cells. Int J Med Mushrooms 18:769–779

    Article  PubMed  Google Scholar 

  • Gui Y, Zhu GS, Callac P, Hyde KD, Parra LA, Chen J, Yang TJ, Huang WB, Gong GL, Liu ZY (2015) Agaricus section Arvenses: three new species in highland subtropical Southwest China. Fungal Biol 119:39–94

    Article  CAS  Google Scholar 

  • Guler P, Akata I, Kutluer F (2009) Antifungal activities of Fomitopsis pinicola (Sw.:Fr.) Karst. and Lactarius vellereus (Pers.) Fr. Afr J Biotechnol 8:3811–3813

    Google Scholar 

  • Güler P, Kutluer F, Erol T, Eren E, Kunduz İ, Biçer H (2012) Screening of antifungal effects of Pseudoclitocybe cyathiformis Bull. (Singer). Int J App Biol Pharma Technol 3:96–99

    Google Scholar 

  • Guo YM (2015) Determination of polysaccharide in Cantharellus cibarius and its antioxidant activity. Technol Dev Chem Ind 44:4–6

    CAS  Google Scholar 

  • Guo X, Hu SQ (2013) Purification and antioxidant activity of exopolysaccharides from Clitocybe maxima. J Southwest Univ (Nat Sci Ed) 35:36–40

    CAS  Google Scholar 

  • Guo SS, Wolf DR (2018) Study on neuroprotective effects of water extract of Fomitopsis pinicola on dopaminergic neurons in vitro. Chin J Pharma 15:582–586

    Google Scholar 

  • Guo CX, Wong KH, Cheung PCK (2011a) Hot water extract of the sclerotium of Polyporus rhinocerus Cooke enhances the immune functions of murine macrophages. Int J Med Mushrooms 13:237–244

    Article  PubMed  Google Scholar 

  • Guo T, Wei L, Sun J, Hou CL, Fan L (2011b) Antioxidant activities of extract and fractions from Tuber indicum Cooke & Massee. Food Chem 127:1634–1640

    Article  CAS  Google Scholar 

  • Guo YJ, Deng GF, Xu XR, Wu S, Li S, Xia EQ, Li F, Chen F, Ling WH, Li HB (2012) Antioxidant capacities, phenolic compounds and polysaccharide contents of 49 edible macro-fungi. Food Funct 3:1195–1205

    Article  CAS  PubMed  Google Scholar 

  • Guo JJ, Li DW, Yao HY, Xie XM, Su MS, Liang YH (2017) Study on the antimicrobial activites of the extracts of Inonotus obliquus fungal substance in vitro. Heilongjiang Med J 30:949–950

    Google Scholar 

  • Guo H, Diao QP, Zhang B, Hou DY (2018a) Optimization of ultrasonic-assisted extraction and antioxidant activity of polysaccharides from Tricholoma populinum. Sci Technol Food Ind 39:180–184

    Google Scholar 

  • Guo HY, Wang GK, Liu JK, Wang G (2018b) Chemical constituents from Perenniporia subacida. Chin Trad Patent Med 40:130–133

    Google Scholar 

  • Gursoy N, Sarikurkcu C, Cengiz M, Solak MH (2009) Antioxidant activities, metal contents, total phenolics and flavonoids of seven Morchella species. Food Chem Toxicol 47:2381–2388

    Article  CAS  PubMed  Google Scholar 

  • Han XQ, Chan BCL, Dong CX, Yang YH, Ko CH, Yue GGL, Chen D, Wong CK, Lau CBS, Tu PF, Shaw PC, Fung KP, Leung PC, Hsiao WL, Han QB (2012) Isolation, structure characterization, and immunomodulating activity of a hyperbranched polysaccharide from the fruiting bodies of Ganoderma sinense. J Agric Food Chem 60:4276–4281

    Article  CAS  PubMed  Google Scholar 

  • Han JJ, Chen YH, Bao L, Yang XL, Liu DL, Li SJ, Zhao F, Liu HW (2013) Anti-inflammatory and cytotoxic cyathane diterpenoids from the medicinal fungus Cyathus africanus. Fitoterapia 84:22–31

    Article  CAS  PubMed  Google Scholar 

  • Han L, Feng N, Feng J, Han W, Ma D, Zhang JS (2014) major chemical components and antioxidant activity of aqueous and ethanolic extracts of Dictyophora echinovolvata mycelia and spent culture broth. Acta Edulis Fungi 21(4):53–57

    Google Scholar 

  • Han CK, Chiang HC, Lin CY, Tang CH, Lee H, Huang DD, Zeng YR, Chuang TN, Huang YL (2015) Comparison of immunomodulatory and anticancer activities in different strains of Tremella fuciformis Berk. Am J Chin Med 43:1637–1655

    Article  PubMed  Google Scholar 

  • Han LR, Cheng D, Wang LR, Wang CL (2016) Structure and immunomodulatory activity of extracellular polysaccharide from Grifola frondosa. Chin J Biotechnol 32:648–656

    Google Scholar 

  • Han Y, Bao HY, Ma L, Chen WJ, Bau T (2019) Prevention and treatment of chronic glomerulonephritis in mice by administrating Irpex lacteus fruiting body extract. Mycosystema 38(3):428–439

    Google Scholar 

  • Hao YJ, Zhao Q, Wang SX, Yang ZL (2016) What is the radicate Oudemansiella cultivated in China? Phytotaxa 286:1–12

    Article  Google Scholar 

  • Hasnat MA, Pervin M, Debnath T, Lim BO (2014) DNA protection, total phenolics and antioxidant potential of the mushroom Russula virescens. J Food Biochem 38:6–17

    Article  CAS  Google Scholar 

  • He LH, Zhou B, Li QS (2011) Chemical constituents of Russula subnigricans. J Northwest For Univ 26:110–113

    Google Scholar 

  • He PX, Wu SS, He XS, Xu CP (2015) The molecular structure and antioxidant activity of polysaccharides from Scleroderma areolatum Ehrenb. J Henan Univ Technol (Nat Sci Ed) 36:45–50

    Google Scholar 

  • Heleno SA, Barros L, Sousa MJ, Martins A, Ferreira ICFR (2010) Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity. Food Chem 119:1443–1450

    Article  CAS  Google Scholar 

  • Heleno SA, Barros L, Martins A, Queiroz MJ, Santos-Buelga C, Ferreira IC (2012) Phenolic, polysaccharidic, and lipidic fractions of mushrooms from northeastern Portugal: chemical compounds with antioxidant properties. J Agric Food Chem 60:4634–4640

    Article  CAS  PubMed  Google Scholar 

  • Heleno SA, Stojković D, Barros L, Glamočlija J, Soković M, Martins A, Queiroz MJRP, Ferreira ICFR (2013) A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia. Food Res Int 51:236–243

    Article  CAS  Google Scholar 

  • Heleno SA, Ferreira ICFR, Ćirić A, Glamočlija J, Martins A, Queiroz MJRP, Soković M (2014) Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents. Food Funct 5:2521–2528

    Article  CAS  PubMed  Google Scholar 

  • Hettwer S, Bänziger S, Suter B, Obermayer B (2017) Grifolin derivatives from Albatrellus ovinus as TRPV1 receptor blockers for cosmetic applications. Int J Cosmet Sci 39:379–385

    Article  CAS  PubMed  Google Scholar 

  • Hou Y, Ding X, Hou W, Song B, Wang T, Wang F, Zhong J (2013a) Immunostimulant activity of a novel polysaccharide isolated from Lactarius deliciosus (L. ex Fr.) Gray. Indian J Pharm Sci 75:393–399

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hou Y, Ding X, Hou W, Zhong J, Zhu H, Ma B, Xu T, Li J (2013b) Anti-microorganism, anti-tumor, and immune activities of a novel polysaccharide isolated from Tricholoma matsutake. Pharmacogn Mag 9:244–249

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hou JX, Zhang JX, Zhao XJ, Duan SN, Liu HX, Guan ZL, Wang LA (2014) Anti-oxidative activity and hepatoprotective effect of lyophilized powder of liquid fermentation products from Cordyceps militaris. Drug Eval Res 37:25–29

    Google Scholar 

  • Hou Y, Ding X, Hou W, Song B, Yan X (2017) Structure elucidation and antitumor activity of a new polysaccharide from Maerkang Tricholoma matsutake. Int J Biol Sci 13:935–948

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hou CX, Yin Y, Qi QY, Song HS, Wang CS (2018) Identification and antimicrobial assays of the bioactive components isolated from the medicinal fungus Cordyceps cicadae. Mycosystema 37:1688–1694

    Google Scholar 

  • Hsieh YH, Chu FH, Wang YS, Chien SC, Chang ST, Shaw JF, Chen CY, Hsiao WW, Kuo YH, Wang SY (2010) Antrocamphin A, an anti-inflammatory principal from the fruiting body of Taiwanofungus camphoratus, and its mechanisms. J Agric Food Chem 58:3153–3158

    Article  CAS  PubMed  Google Scholar 

  • Hu HH, Zhang ZY, Lei ZF, Yang YN, Sugiura N (2009) Comparative study of antioxidant activity and antiproliferative effect of hot water and ethanol extracts from the mushroom Inonotus obliquus. J Biosci Bioeng 107:42–48

    Article  CAS  PubMed  Google Scholar 

  • Hu QX, Wang HX, Ng TB (2012) Isolation and purification of polysaccharides with anti-tumor activity from Pholiota adiposa (Batsch) P. Kumm. (higher Basidiomycetes). Int J Med Mushrooms 14:271–284

    Article  PubMed  Google Scholar 

  • Hu LL, Ma QY, Huang SZ, Dai HF (2013) Study on the chemical constituents from Ganoderma tropicum. Chin J Med Chem 23:115–119

    CAS  Google Scholar 

  • Hu W, Liu S, Zhang YX, Xun D, Xu CP (2014a) Mycelial fermentation characteristics and antiproliferative activity of Phellinus vaninii Ljup. Pharmacogn Mag 10:430–434

    Article  PubMed  PubMed Central  Google Scholar 

  • Hu XY, Wang CM, Zhang G, Jiang JZ, Long YG, Yu YS (2014b) Artificial cultivation of and their inhibitory effect on tumor cells. Chin J Exper Trad Med Formulae 20:161–164

    CAS  Google Scholar 

  • Hu K, Cheng WM, Li CR (2017a) Separation and structural identification of antifungal substances in the fermentation broth of Cordyceps cicadae. Mycosystema 36:332–338

    Google Scholar 

  • Hu T, Huang QL, Wong KH, Yang H (2017b) Structure, molecular conformation, and immunomodulatory activity of four polysaccharide fractions from Lignosus rhinocerotis sclerotia. Int J Biol Macromol 94:423–430

    Article  CAS  PubMed  Google Scholar 

  • Hu XL, Tian XM, Li WX, Sun YN, Zhang X, Yu G, Li M (2017c) Extraction and immune modulatory activities in vitro of polysaccharides from Lepista sordida mycelia. Food Sci 38:185–190

    Google Scholar 

  • Hu YP, Wang J, Zheng L, Tian XL, Dai L, Lin LH, Wang LA (2018a) Isolation, purification, antioxidant and antitumor activities of polysaccharides from Laetiporus sulphureus. Mod Chin Med 20:1131–1136

    Google Scholar 

  • Hu YP, Zhang BQ, Zhang JX, Zhao LQ, Wang LA (2018b) Chemical constituents of fruiting bodies of Coprinus comatus and their activities against diabetes. Mycosystema 37:371–378

    Google Scholar 

  • Hu YP, Zhang JX, Zhao LQ, Lin LH, Wang LA (2018c) Physicochemical property and antioxidant activity of polysaccharide from Gymnopilus spectabilis. Nat Prod Res Dev 30:274–279

    Google Scholar 

  • Huang WQ (2010) Study on the antitumor activities of Lasiosphaera fenzlii. Contemp Med 16:34–35

    Google Scholar 

  • Huang M, Bau T (2018) New findings of Coprinellus species (Psathyrellaceae, Agaricales) in China. Phytotaxa 374:119–128

    Article  Google Scholar 

  • Huang CC, Hsu MC, Huang WC, Yang HR, Hou CC (2012a) Triterpenoid-rich extract from Antrodia camphorata improves physical fatigue and exercise performance in mice. Evid Based Compl Alt. https://doi.org/10.1155/2012/364741

    Article  Google Scholar 

  • Huang HC, Liaw CC, Yang HL, Hseu YC, Kuo HT, Tsai YC, Chien SC, Amagaya S, Chen YC, Kuo YH (2012b) Lanostane triterpenoids and sterols from Antrodia camphorata. Phytochemistry 84:177–183

    Article  CAS  PubMed  Google Scholar 

  • Huang TZ, Du DY, Chen YQ, Yuan B, Ju XY, Feng YJ, Wang L, Jiang JH (2012c) Chemical constituents and antitumor activity of fruiting body of Fomes fomentarius. Mycosystema 5:775–783

    Google Scholar 

  • Huang YT, Li NS, Wan JB, Zhang DZ, Yan CY (2015) Structural characterization and antioxidant activity of a novel heteropolysaccharide from the submerged fermentation mycelia of Ganoderma capense. Carbohydr Polym 134:752–760

    Article  CAS  PubMed  Google Scholar 

  • Huang CL, Zheng JL, Li FL, Gong JL (2016a) Effect of pachymaran to the antioxidant capacity and Bax, Bcl-2 protein expression of renal tissue in mice with type II diabetes. J Food Sci Biotechnol 35:82–88

    CAS  Google Scholar 

  • Huang CL, Zheng JL, Li FL, Gong JL (2016b) Hypoglycemic effects of polysaccharides from Wolfiporia cocos (Schw.) Ryv. & Cilbn. in type II diabetic mice. Food Res Dev 37:21–25

    Google Scholar 

  • Huang J, Li AX, Zhou X, Wang SM (2016c) The immune function and anti-tumor effects of Ganoderma tsugae fermentation product on H22 liver ascites tumor mice. J Pharm Res 35:575–578

    CAS  Google Scholar 

  • Huang JF, Huang YQ, Lai YD, Ou YX, Chen JM, Zhang XF, Pan YT (2016d) In vivo protective and repairde effects of polysaccharide from Grifola frondosa on gastric mucosa trauma. Mycosystema 35:326–334

    CAS  Google Scholar 

  • Huang M, Zhao P, Xiong M, Zhou Q, Zheng S, Ma X, Xu C, Yang J, Yang X, Zhang TC (2016e) Antidiabetic activity of perylenequinonoid-rich extract from Shiraia bambusicola in KK-Ay mice with spontaneous type 2 diabetes mellitus. J Ethnopharmacol 191:71–81

    Article  CAS  PubMed  Google Scholar 

  • Huang J, Huang YY, Liu DM, Chen SQ, Pan WC (2017a) Optimization of extraction process of polysaccharides from wild Lactarius volemus by response surface method and investigation of antioxidant activity. Sci Technol Food Ind 38:55–60

    Google Scholar 

  • Huang XL, Zhu PX, Hu YL, Ge XY (2017b) The improvement of Cordyceps militaris polysaccharides on acute liver injuried mice model induced by alcohol. Mycosystema 36:242–250

    Google Scholar 

  • Huang YT, Zou F, Sun Q, Ye DW, Wang K, Liu CL (2018) Extraction and antioxidant activities of polysaccharides from Cortinarius collinitus fruiting bodies. Acta Edulis Fungi 25:72–78

    Google Scholar 

  • Jameel GH, Al-Ezzy AIA (2017) Evaluation of antifungal activity of Calvatia Craniiformis and iver-mectin as novel alternative therapies for Aspergillus niger associated acute otitis media with special refer to sociodemographic factors among rural children of Diyala Province-Iraq. Int J Pharm Clin Res 9:581–589

    Article  Google Scholar 

  • Jaszek M, Osińska-Jaroszuk M, Janusz G, Matuszewska A, Stefaniuk D, Sulej J, Polak J, Ruminowicz M, Grzywnowicz K, Jarosz-Wilkołazka A (2013) New bioactive fungal molecules with high antioxidant and antimicrobial capacity isolated from Cerrena unicolor idiophasic cultures. BioMed Res Int. https://doi.org/10.1155/2013/497492

    Article  PubMed  PubMed Central  Google Scholar 

  • Ji HF, Zhang LW, Wang Q, Zhang HR, Song RQ (2011) Antimicrobial activity and stability of extraction from Lactarius vellereus fermenting liquor. J Harbin Univ Comm (Nat Sci Ed) 27:581–586

    CAS  Google Scholar 

  • Jia XW, Zheng K, Liu S, Xu CP (2015) Optimization, purification, characterization, and antioxidant activity of exopolysaccharide produced by the northern tooth mushroom, Climacodon septentrionalis (Basidiomycota). Int J Med Mushrooms 17:857–866

    Article  PubMed  Google Scholar 

  • Jia HQ, Liu W, Lang L, Zheng RF, Ran L, Yan J, Gou XJ, He G (2017) Isolation and purification, structure identification and antioxidant activity of Monascus purpureus exopolysaccharide. Sci Technol Food Ind 38:92–96

    Google Scholar 

  • Jiang ZK, Wang XF (2017) Improvement effect of Poria cocos peels water extract on liver fibrosis in rats induced by carbon tetrachloride. China Pharm 28:3065–3068

    Google Scholar 

  • Jiang YJ, Wang HY, Xie BG, Deng YJ, Gong LY, Zhao C (2011) Antioxidant activities of mushrooms and extraction process optimization for Dictyophora echinovolvata. Chin J Trop Crops 32:1075–1081

    Google Scholar 

  • Jiang JP, Xiong YK, Yu B, Zhang SL, Zhang CC (2013) Effect of Tremella mesenterica polysacchrides on pulmonary function in asthmatic model of guinea pigs. Chin J Tradit Chin Med Pharm 28:206–209

    CAS  Google Scholar 

  • Jiang HT, Wu YL, Wang RL, Wang ZJ, Hua C (2014a) Protective effect of polysaccharides from Cordyceps militaris stroma against alcohol-induced acute liver injury in mice. Food Sci 35:223–227

    CAS  Google Scholar 

  • Jiang J, Yang Y, Qiao YR, Zhou S, Liu YF, Zhang JS, Feng ZY (2014b) Physicochemical properties and biological activities of decolored and not decolored polysaccharides from Hericium erinaceus. Mycosystema 33:78–86

    CAS  Google Scholar 

  • Jiang N, Li Y, Wang WJ, Imoulan A, Yao YJ (2017) Total phenolic content and antioxidant activity of mycelial extracts from the medicinal fungus Paecilomyces hepiali (Ascomycetes). Int J Med Mushrooms 19:35–44

    Article  PubMed  Google Scholar 

  • Jiao CW, Xie YZ, Yang XL, Li HR, Li XM, Pan HH, Cai MH, Zhong HM, Yang BB (2013) Anticancer activity of Amauroderma rude. PloS ONE 8:e66504

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Jiao JL, Zhang MS, Fang YK, Ning AH, Zhong MT, Huang M (2018a) Anti-tumor effect of protein LP1 from Lentinula edodes C91-3 in mice bearing hepatic carcinoma H22 cell. Chin J Microecol 30:895–899

    Google Scholar 

  • Jiao YC, Kuang H, Hu JJ, Chen QH (2018b) Structural characterization and anti-hypoxia activities of polysaccharides from the sporocarp, fermentation broth and cultured mycelium of Agaricus bitorquis (Quél.) Sacc. Chaidam in mice. J Funct Foods 51:75–85

    Article  CAS  Google Scholar 

  • Jiao YC, Kuang H, Wu JN, He CR, Chen QH (2018c) The anti-fatigue activities of polysaccharides extracted from the Agaricus bitorquis (Quél.) Sacc. Chaidam. Mod Food Sci Technol 34:24–30

    Google Scholar 

  • Jin X, Chen C, Chen ZQ, Huang WL (2017) Phylogenetic analysis on different truffles and immunomodulatory effects on mice. Nat Prod Res Dev 29:1677–1682

    Google Scholar 

  • Jin SS, Liu X, Hou RL, Yu QM, Wang DT, Hu KH, Zheng MF, Fu JS (2018) Identification and biological activity of a medicinal Inonotus. J Northwest Agric For Univ (Nat Sci Ed) 46(12):130–139

    Google Scholar 

  • Jin LD, Ou WB, Xu XQ (2019) Preliminary study on tumor cell activity inhibition effect of triterpene from submerged fermentation of Inonotus obliquus. J Zhejiang Sci Technol Univ 41:98–105

    Google Scholar 

  • Jo WS, Choi YJ, Kim HJ, Lee JY, Nam BH, Lee JD, Lee SW, Seo SY, Jeong MH (2010) The anti-inflammatory effects of water extract from Cordyceps militaris in murine macrophage. Mycobiology 38:46–51

    Article  PubMed  PubMed Central  Google Scholar 

  • John PA, Wong KH, Naidu M, Sabaratnam V, David P (2013) Combination effects of curcumin and aqueous extract of lignosus rhinocerotis mycelium on neurite outgrowth stimulation activity in PC-12 cells. Nat Prod Commun 8:711–714

    CAS  Google Scholar 

  • Johnsy G, Kaviyarasan V (2011) Antimicrobial and antioxidant properties of Trametes gibbosa (pers) Fr. J Pharm Res 4:3939–3942

    Google Scholar 

  • Kaewnarin K, Suwannarach N, Kumla J, Lumyong S (2016) Phenolic profile of various wild edible mushroom extracts from Thailand and their antioxidant properties, anti-tyrosinase and hyperglycaemic inhibitory activities. J Funct Foods 27:352–364

    Article  CAS  Google Scholar 

  • Kalyoncu F, Oskay M, Kayalar H (2010) Antioxidant activity of the mycelium of 21 wild mushroom species. Mycology 1:195–199

    Article  CAS  Google Scholar 

  • Kang MG, Kim YH, Bolormaa Z, Kim MK, Seo GS, Lee JS (2013) Characterization of an antihypertensive angiotensin I-converting enzyme inhibitory peptide from the edible mushroom Hypsizygus marmoreus. BioMed Res Int. https://doi.org/10.1155/2013/283964

    Article  PubMed  PubMed Central  Google Scholar 

  • Karaman M, Stahl M, Vulić J, Vesić M, Čanadanović-Brunet J (2014) Wild-growing lignicolous mushroom species as sources of novel agents with antioxidative and antibacterial potentials. Int J Food Sci Nutr 65:311–319

    Article  CAS  PubMed  Google Scholar 

  • Kaygusuz O, Kaygusuz M, Dodurga Y, Seçme M, Herken EN, Gezer K (2017) Assessment of the antimicrobial, antioxidant and cytotoxic activities of the wild edible mushroom Agaricus lanipes (F.H. Møller & Jul. Schäff.) Hlaváček. Cytotechnology 69:135–144

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ke RD, Lin SF, Chen Y, Ji CR, Shu QG (2010) Analysis of chemical composition of polysaccharides from Poria cocos Wolf and its anti-tumor activity by NMR spectroscopy. Carbohydr Polym 80:31–34

    Article  CAS  Google Scholar 

  • Khatua S, Acharya K (2017) Alkaline extractive crude polysaccharide from Russula senecis possesses antioxidant potential and stimulates innate immunity response. J Pharm Pharmacol 69:1817–1828

    Article  CAS  PubMed  Google Scholar 

  • Khatua S, Roy T, Acharya K (2013) Antioxidant and free radical scavenging capacity of phenolic extract from Russula laurocerasi. Asian J Pharm Clin Res 6:156–160

    Google Scholar 

  • Kim HS, Kim JY, Ryu HS, Park HG, Kim YO, Kang JS, Kim HM, Hong JT, Kim Y, Han SB (2010) Induction of dendritic cell maturation by β-glucan isolated from Sparassis crispa. Int Immunopharmacol 10:1284–1294

    Article  CAS  PubMed  Google Scholar 

  • Kim SP, Kang MY, Kim JH, Nam SH, Friedman M (2011) Composition and mechanism of antitumor effects of Hericium erinaceus mushroom extracts in tumor-bearing mice. J Agric Food Chem 59:9861–9869

    Article  CAS  PubMed  Google Scholar 

  • Kim HH, Lee S, Singh TSK, Choi JK, Shin TY, Kim SH (2012) Sparassis crispa suppresses mast cell-mediated allergic inflammation: role of calcium, mitogen-activated protein kinase and nuclear factor-κB. Int J Mol Med 30:344–350

    Article  PubMed  Google Scholar 

  • Kim TW, Yoon DH, Cho JY, Sung GH (2013) Cordyceps scarabaeicola inhibits inflammatory mediators by suppressing NF-κB activation. FASEB J 27:lb207

    Google Scholar 

  • Kim HG, Yang WS, Sung GH, Kim JH, Baek GS, Kim E, Yang S, Park YC, Sung JM, Yoon DH, Kim TW, Hong S, Kim JH, Cho JY (2014) IKK β-targeted anti-inflammatory activities of a butanol fraction of artificially cultivated Cordyceps pruinosa fruit bodies. Evid Based Compl Alt. https://doi.org/10.1155/2014/562467

    Article  Google Scholar 

  • Kim KC, Lee IS, Yoo ID, Ha BJ (2015) Sesquiterpenes from the fruiting bodies of Ramaria formosa and their human neutrophil elastase inhibitory activity. Chem Pharm Bull 63:554–557

    Article  Google Scholar 

  • Kim S, So HM, Roh HS, Kim J, Yu JS, Lee S, Seok S, Pang C, Baek KH, Kim KH (2017) Vulpinic acid contributes to the cytotoxicity of Pulveroboletus ravenelii to human cancer cells by inducing apoptosis. R Soc Chem 7:35297–35304

    CAS  Google Scholar 

  • Klančnik A, Megušar P, Sterniša M, Jeršek B, Bucar F, Smole Možina S, Kos J, Sabotič J (2017) Aqueous extracts of wild mushrooms show antimicrobial and antiadhesion activities against bacteria and fungi. Phytother Res 31:1971–1976

    Article  PubMed  CAS  Google Scholar 

  • Klaus A, Kozarski M, Niksic M, Jakovljevic D, Todorovic N, van Griensven LJLD (2011) Antioxidative activities and chemical characterization of polysaccharides extracted from the basidiomycete Schizophyllum commune. LWT Food Sci Technol 44:2005–2011

    Article  CAS  Google Scholar 

  • Ko HJ, Song AR, Lai MN, Ng LT (2011) Immunomodulatory properties of Xylaria nigripes in peritoneal macrophage cells of Balb/c mice. J Ethnopharmacol 138:762–768

    Article  PubMed  Google Scholar 

  • Kolundžić M, Grozdanić NĐ, Dodevska M, Milenković M, Sisto F, Miani A, Farronato G, Kundaković T (2016) Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae. Ind Crop Prod 79:110–115

    Article  CAS  Google Scholar 

  • Kosanić M, Ranković B, Dasić M (2013) Antioxidant and antimicrobial properties of mushrooms. Bulg J Agric Sci 19:1040–1046

    Google Scholar 

  • Kosanić M, Ranković B, Rančić A, Stanojković T (2016) Evaluation of metal concentration and antioxidant, antimicrobial, and anticancer potentials of two edible mushrooms Lactarius deliciosus and Macrolepiota procera. J Food Drug Anal 24:477–484

    Article  PubMed  CAS  Google Scholar 

  • Kovács B, Zomborszki ZP, Orbán-Gyapai O, Csupor-Löffler B, Liktor-Busa E, Lázár A, Papp V, Urbán E, Hohmann J, Ványolós A (2017) Investigation of antimicrobial, antioxidant, and xanthine oxidase-inhibitory activities of Phellinus (Agaricomycetes) mushroom species native to central Europe. Int J Med Mushrooms 19:387–394

    Article  PubMed  Google Scholar 

  • Kozarski M, Klaus A, Niksic M, Jakovljevic D, Helsper JPFG, Van Griensven LJLD (2011) Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus. Food Chem 129:1667–1675

    Article  CAS  Google Scholar 

  • Kozarski M, Klaus A, Nikšić M, Vrvić MM, Todorović N, Jakovljević D, Van Griensven LJLD (2012) Antioxidative activities and chemical characterization of polysaccharide extracts from the widely used mushrooms Ganoderma applanatum, Ganoderma lucidum, Lentinus edodes and Trametes versicolor. J Food Compos Anal 26:144–153

    Article  CAS  Google Scholar 

  • Krupodorova TA, Rybalko S, Barshteyn V (2014) Antiviral activity of Basidiomycete mycelia against influenza type A (serotype H1N1) and herpes simplex virus type 2 in cell culture. Virol Sin 29:284–290

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Krupodorova TA, Barshteyn VY, Zabeida EF, Pokas EV (2016) Antibacterial activity of macromycetes mycelia and culture liquid. Microbiol Biotechnol Lett 44:246–253

    Article  CAS  Google Scholar 

  • Kumar VB, Yuan TC, Liou JW, Yang CJ, Sung PJ, Weng CF (2011) Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles. Mutat Res-Fund Mol M 707:42–52

    Article  CAS  Google Scholar 

  • Kumar A, Suman S, Kumar R, Singh JK, Ali M (2014) Hepatoprotective effect of edible oyster mushroom Pleurotus cornucopiae against sodium arsenite induced hepatotoxicity in rats. Int J Phytomed 9:528–678

    Google Scholar 

  • Kwon AH, Qiu Z, Hashimoto M, Yamamoto K, Kimura T (2009) Effects of medicinal mushroom (Sparassis crispa) on wound healing in streptozotocin-induced diabetic rats. Am J Surg 197:503–509

    Article  PubMed  Google Scholar 

  • Kwon YJ, Kim MH, Choi JS, Lee TS (2014) Free radical scavenging, anti-inflammatory and melannin synthesis inhibitory activities of Gloeostereum incarnatum. J Mushroom 12:107–116

    Article  Google Scholar 

  • Lai MN, Ng LT (2013) Antioxidant and antiedema properties of solid-state cultured honey mushroom, Armillaria mellea (higher Basidiomycetes), extracts and their polysaccharide and polyphenol contents. Int J Med Mushrooms 15:1–8

    Article  CAS  PubMed  Google Scholar 

  • Lai TK, Biswas G, Chatterjee S, Dutta A, Pal C, Banerji J, Bhuvanesh N, Reibenspies JH, Acharya K (2012) Leishmanicidal and anticandidal activity of constituents of Indian edible mushroom Astraeus hygrometricus. Chem Biodivers 9:1517–1524

    Article  CAS  PubMed  Google Scholar 

  • Lan WQ, Hu XY, Yan XY, Zhao Y, Pan YJ, Sun XH (2017) Antibacterial effect of extracts from Dictyophora indusiata Fisscher against foodborne pathogen. J China Inst Food Sci Technol 17:108–112

    Google Scholar 

  • Lau BF, Abdullah N, Aminudin N, Lee HB (2013) Chemical composition and cellular toxicity of ethnobotanical-based hot and cold aqueous preparations of the tiger’s milk mushroom (Lignosus rhinocerotis). J Ethnopharmacol 150:252–262

    Article  CAS  PubMed  Google Scholar 

  • Lau BF, Abdullah N, Aminudin N, Lee HB, Yap KC, Sabaratnam V (2014) The potential of mycelium and culture broth of Lignosus rhinocerotis as substitutes for the naturally occurring sclerotium with regard to antioxidant capacity, cytotoxic effect, and low-molecular-weight chemical constituents. PloS ONE 9:e102509

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Lavi I, Levinson D, Peri I, Nimri L, Hadar Y, Schwartz B (2010a) Orally administered glucans from the edible mushroom Pleurotus pulmonarius reduce acute inflammation in dextran sulfate sodium-induced experimental colitis. Br J Nutr 103:393–402

    Article  CAS  PubMed  Google Scholar 

  • Lavi I, Levinson D, Peri I, Tekoah Y, Hadar Y, Schwartz B (2010b) Chemical characterization, antiproliferative and antiadhesive properties of polysaccharides extracted from Pleurotus pulmonarius mycelium and fruiting bodies. Appl Microbiol Biotechnol 85:1977–1990

    Article  CAS  PubMed  Google Scholar 

  • Leal AR, Barros L, Barreira JCM, Sousa MJ, Martins A, Santos-Buelga C, Ferreira ICFR (2013) Portuguese wild mushrooms at the “pharma–nutrition” interface: nutritional characterization and antioxidant properties. Food Res Int 50:1–9

    Article  CAS  Google Scholar 

  • Lee SY, Lee YG, Byeon SE, Han S, Choi SS, Kim AR, Lee J, Lee SJ, Hong S, Cho JY (2010) Mitogen activated protein kinases are prime signalling enzymes in nitric oxide production induced by soluble β-glucan from Sparassis crispa. Arch Pharm Res 33:1753–1760

    Article  CAS  PubMed  Google Scholar 

  • Lee D, Boo KH, Lee JM, Viet CD, Quyen N, Unno T, Cho M, Riu KZ, Lee DS (2012a) Anti-viral activity of Hydnellum concrescens, a medicinal mushroom. Afr J Biotechnol 11:15241–15245

    Article  Google Scholar 

  • Lee MI, Tan NH, Fung SY, Tan CS, Ng ST (2012b) The antiproliferative activity of sclerotia of Lignosus rhinocerus (tiger milk mushroom). Evid Based Compl Alt. https://doi.org/10.1155/2012/697603

    Article  Google Scholar 

  • Lee YP, Tsai WC, Ko CJ, Rao YK, Yang CR, Chen DR, Yang MH, Yang CC, Tzeng YM (2012c) Anticancer effects of eleven triterpenoids derived from Antrodia camphorata. Anticancer Res 32:2727–2734

    CAS  PubMed  Google Scholar 

  • Lee D, Boo KH, Lee JM, Unno T, Lee WS, Cho M, Riu KZ, Lee DS (2013) Anti-viral activity of blue chanterelle (Polyozellus multiplex) that inhibits α-glucosidase. Food Sci Biotechnol 22:747–750

    Article  Google Scholar 

  • Lee CI, Wu CC, Hsieh SL, Lee CL, Chang YP, Chang CC, Wang YZ, Wang JJ (2014a) Anticancer effects on human pancreatic cancer cells of triterpenoids, polysaccharides and 1,3-β-d-glucan derived from the fruiting body of Antrodia camphorata. Food Funct 5:3224–3232

    Article  CAS  PubMed  Google Scholar 

  • Lee SS, Tan NG, Fung SY, Sim SM, Tan CS, Ng ST (2014b) Anti-inflammatory effect of the sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden, the Tiger Milk mushroom. BMC Complement Altern Med 14:359

    Article  PubMed  PubMed Central  Google Scholar 

  • Lee HH, Lee S, Lee K, Shin YS, Kang H, Cho H (2015) Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis. DARU J Pharm Sci US 23:35

    Article  CAS  Google Scholar 

  • Lei P, Wu YZ, Zhang WJ, Xie YH, Du F (2015) Inhibitory effect of Phellinus igniarius mycelium on murine S180sarcoma. Acta Edulis Fungi 22(3):60–63

    Google Scholar 

  • Lemieszek MK, Nunes FM, Cardoso C, Marques G, Rzeski W (2018) Neuroprotective properties of Cantharellus cibarius polysaccharide fractions in differentin vitro models of neurodegeneration. Carbohydr Polym 197:598–607

    Article  CAS  PubMed  Google Scholar 

  • Li SZ (1957) Compendium materia medica, 1578. Commercial Press, Beijing, Reprinted

    Google Scholar 

  • Li H (2017) Extraction, purification, characterization and antioxidant activities of polysaccharides from Ramaria botrytis (Pers.) Ricken. Chem Cent J 11:24

    Article  PubMed  PubMed Central  Google Scholar 

  • Li ZJ, Bao HY (2018) Correlation between different soaking way and content of diisobutyl phthalate in Auricularia heimuer. Mycosystema 37:389–394

    Google Scholar 

  • Li XY, Fan L (2015) Antioxidant activities of different extracts from Tuber liyuanum. Mycosystema 34:456–472

    Google Scholar 

  • Li YQ, Hu JW (2010) Study on anti-hyperglycemic activity of polysaccharides of Inonotus hispidus (Bull.Fr.) P. Karst. Edible Fungi China 29:49–51

    Google Scholar 

  • Li J, Wei J (2017) Study on the anti-fatigue and improving immune function effects of Agaricus blazei polysaccharide. Food Res Dev 38:201–204

    Google Scholar 

  • Li XQ, Xu W (2011) TLR4-mediated activation of macrophages by the polysaccharide fraction from Polyporus umbellatus (Pers.) Fries. J Ethnopharmacol 135:1–6

    Article  CAS  PubMed  Google Scholar 

  • Li MX, Yu WY (2018) Inhibition effect of Polyporus polysaccharide on Lewis lung cancer in mice and influences on peripheral blood cells moderation. Chin J Trad Med Sci Technol 25:653–655

    Google Scholar 

  • Li B, Lu F, Suo XM, Nan HJ, Li B (2010) Antioxidant properties of cap and stipe from Coprinus comatus. Molecules 15:1473–1486

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Li FR, Chou LL, Fan XT (2011) Experimental studies on effects of EEPP on learning and memory dysfunctions. J Beihua Univ (Nat Sci) 12:172–176

    Google Scholar 

  • Li BY, Wu XL, Song B, Li TH, Zhong JX, Chen HQ (2013a) Distribution of the medicinal Ganoderma ssp in Hainan. Guangdong Agri Sci 3:171–173

    Google Scholar 

  • Li HJ, Feng CP, Chang MC, Cheng HY, Wang XW (2013b) Effects of Agaricus blazei Murill polysaccharide on splenic histomorphology and mRNA expression of the cytokines in the lead-poisoning rats. Acta Nutrimenta Sin 35(2):176–180

    Google Scholar 

  • Li YX, Han JJ, Yang XL, Li HR, Wang YQ, Wang SJ, Bao L (2013c) Bioactive composition of the solid culture of the edible mushroom Pleurotus citrinopileatus on rice and the antioxidant effect evaluation. Mycosystema 32:876–882

    CAS  Google Scholar 

  • Li ZM, Ke CL, Zeng XX (2013d) Extraction and immunomodulatory activity of polysaccharide from Pholiota dinghuensis Bi. Sci Technol Food Ind 34:251–255

    Google Scholar 

  • Li ZM, Xu H, Zeng XX (2013e) Antibacterial and antioxidant activity of polysaccharide from Pholiota dinghuensis Bi. Food Fermen Ind 39:167–170

    Google Scholar 

  • Li H, Lee HS, Kim SH, Moon BK, Lee C (2014a) Antioxidant and anti-inflammatory activities of methanol extracts of Tremella fuciformis and its major phenolic acids. J Food Sci 79:C460–C468

    Article  CAS  PubMed  Google Scholar 

  • Li W, Bao HY, Bau T (2014b) Chemical constituents and antioxidant activities of Laetiporus cremeiporus. Mycosystema 33:365–374

    Google Scholar 

  • Li W, Zhou W, Lee DS, Shim SH, Kim YC, Kim YH (2014c) Hericirine, a novel anti-inflammatory alkaloid from Hericium erinaceum. Tetrahedron Lett 55:4086–4090

    Article  CAS  Google Scholar 

  • Li ZP, Shang Y, Xiang L, Lu XM (2014d) Antioxidant activities of water extracts from fruiting bodies of two Albatrellus species. Sci Technol Food Ind 35:104–107

    Google Scholar 

  • Li F, Xie CM, Zhao Y, Zhang YH, Li JL, Du CM, Zhao YX (2015a) A comparative analysis on antioxidant activity for four kinds of Lepista epiphyte. J Anhui Agric Sci 43:15–17

    Google Scholar 

  • Li HJ, Xie JW, Zhang S, Zhou YJ, Ma PB, Zhou J, Sun CY (2015b) Amanita subpallidorosea, a new lethal fungus from China. Mycol Prog 14:43

    Article  Google Scholar 

  • Li MH, Wu HC, Yao HJ, Lin CC, Wen SF, Pan IH (2015c) Antrodia cinnamomea extract inhibits Th17 cell differentiation and ameliorates imiquimod-induced psoriasiform skin inflammation. Am J Chin Med 43:1401–1417

    Article  PubMed  Google Scholar 

  • Li MZ, Miao SS, Mao XH, Sun J (2015d) Lepista sordida polysaccharides LSPb1 inhibiting angiogenesis in laryngeal cancer cell xenograft model. J Harbin Med Univ 49:34–37

    CAS  Google Scholar 

  • Li SC, Yang XM, Ma HL, Yan JK, Guo DZ (2015e) Purification, characterization and antitumor activity of polysaccharides extracted from Phellinus igniarius mycelia. Carbohydr Polym 133:24–30

    Article  CAS  PubMed  Google Scholar 

  • Li TH, Hu HP, Deng WQ, Wu SH, Wang DM, Tsering T (2015f) Ganoderma leucocontextum, a new member of the G. lucidum complex from southwestern China. Mycoscience 56:81–85

    Article  Google Scholar 

  • Li Y, Li TH, Yang ZL, Bau T, Dai YC (2015g) Atlas of China macrofungal resources. ZhongYuan Farmers Press, Zhengzhou, pp 1–1351

    Google Scholar 

  • Li ZM, Ke CL, Wang YB (2015h) Hepatoprotective effect and antioxidant activity of crude polysaccharide from Calvatia gigantea mycelium grown in submerged culture. Acta Edulis Fungi 22:70–74

    Google Scholar 

  • Li J, Zhou WJ, Zhao SH, Lv HL (2016a) Isolation, purification, antioxidant and antitumor activities of polysaccharides from Morchella esculenta. Nat Prod Res Dev 28:1351–1356

    Google Scholar 

  • Li SS, Zhang WF, Wang L, Chen YY (2016b) Ultrasonic microwave assisted extraction technology of polysaccharides from Pleurotus ferulae and its antioxidant activity. Food Res Dev 37:72–76

    Google Scholar 

  • Li CJ, Yang Y, Wu D, Liu YF, Li QZ, Wang WH, Wu Y, Zhang JS, Zhang HN (2017a) Effects of ultrasonic degradation on physicochemical properties and in vitro immunological activity of Hericium erinaceus polysaccharide. Acta Edulis Fungi 24:44–49

    Google Scholar 

  • Li HJ, Meng G, Zheng F, Yuan Y, Si J (2017b) Antioxidant activities of Perenniporia robiniophila, P. subacida, and P. fraxinea during liquid cultivation. Mycosystema 36:229–241

    CAS  Google Scholar 

  • Li L, Li L, Liu MJ, Shu P (2017c) A research based on response-surface method for optimization of microwave-assisted extraction of polysaccharides from Boletus auripes Pk. and its antioxidation. Sci Technol Food Ind 38:293–318

    Article  Google Scholar 

  • Li MH, Sun YX, Zheng Y, Lei Y, Bao M (2017d) Extraction process of polysaccharide content of mycelium and extracellular polysaccharide from Morchella crassipes. J Fungal Res 25:195–200

    Google Scholar 

  • Li NN, Li HM, Xue CM, Zhao YX, Li JL, Du CM, Li L, Jing GY (2017e) The antioxidant activity of crude polysaccharide in Lepista nuda. J Anhui Agric Sci 45:63–65

    Google Scholar 

  • Li TT, Huang ZR, Pan YY, Jia RB, Hua PP (2017f) Analysis of chemical constituents of Ganoderma lucidum and its antioxidant activity in polysaccharides and triterpenoids. Sci Technol Food Ind 38:63–73

    Google Scholar 

  • Li ZW, Kuang Y, Tang SN, Li K, Huang Y, Qiao X, Yu SW, Tzeng YM, Lo JY, Ye M (2017g) Hepatoprotective activities of Antrodia camphorata and its triterpenoid compounds against CCl4-induced liver injury in mice. J Ethnopharmacol 206:31–39

    Article  CAS  PubMed  Google Scholar 

  • Li A, Yuan WB, Zhang ZG, Bai ZX, Du DJ, Wang SM (2018a) Study on the immunological activity of Irpex lacteus fermentation fluid and its distinct components. J Pharm Res 37:72–74

    Google Scholar 

  • Li CR, Hywel-Jones N, Cao YP, Nam SH, Li ZZ (2018b) Tolypocladium dujiaolongae sp. nov. and its allies. Mycotaxon 133:229–241

    Article  Google Scholar 

  • Li QJ, Bao HY, Bau T, Li Y (2018c) Influence of Inonotus hispidus in hemorheology in rat model with blood stasis due to cold syndrome and analysis on spectral efficiency. J Jilin Univ (Med Ed) 44:30–35

    Google Scholar 

  • Liang JF, Yang ZL (2011) Two new taxa close to Lepiota cristata from China. Mycotaxon 116:387–394

    Article  Google Scholar 

  • Liang JD, Han YF, Tian WY, Liang ZQ, Li ZZ (2018) Advances in bioactive components in Cordyceps takaomontana and their pharmacological effects. Acta Edulis Fungi 25:113–119

    Google Scholar 

  • Liao X, Li WZ, Zheng SJ, Lu KK, Shi F, Wu SR, Ming J (2017) Fractionation and antioxidant activity of polyphenols from Morchella angusticeps Peck. Food Sci 38:26–31

    Google Scholar 

  • Liew GM, Khong HY, Kutoi CJ, Sayok AK (2015) Phytochemical screening, antimicrobial and antioxidant activities of selected fungi from Mount Singai, Sarawak, Malaysia. Int J Res Stud Biosci 3:191–197

    Google Scholar 

  • Liktor-Busa E, Kovács B, Urbán E, Hohmann J, Ványolós A (2016) Investigation of Hungarian mushrooms for antibacterial activity and synergistic effects with standard antibiotics against resistant bacterial strains. Lett Appl Microbiol 62:437–443

    Article  CAS  PubMed  Google Scholar 

  • Lim Y, Lee S, Kim JY, Shin JH, Kwon O (2016) A Phellinus baumii-based supplement containing Salvia miltiorrhiza Bunge improves atherothrombotic profiles through endothelial nitric oxide synthase and cyclooxygenase pathways in vitro and in vivo. J Funct Foods 24:231–243

    Article  CAS  Google Scholar 

  • Lin CQ, Lin RB, Chen JC, Zhang H, Lin XJ (2013) Radical scavenging and Fe2+ chelating activities of aqueous, ethanolic and ethyl acetate extracts of Dictyophora echinovolvata pilei. Acta Edulis Fungi 20(2):32–36

    Google Scholar 

  • Lin WC, Deng JS, Huang SS, Wu SH, Chen CC, Lin WR, Lin HY, Huang GJ (2017a) Anti-inflammatory activity of Sanghuangporus sanghuang mycelium. Int J Mol Sci 18:347

    Article  PubMed Central  CAS  Google Scholar 

  • Lin WC, Deng JS, Huang SS, Wu SH, Lin HY, Huang GJ (2017b) Evaluation of antioxidant, anti-inflammatory and anti-proliferative activities of ethanol extracts from different varieties of Sanghuang species. RSC Adv 7:7780–7788

    Article  CAS  Google Scholar 

  • Lin CQ, Wang YH, Chen JC, Zhang H, Lin XJ, Lin RB (2018a) GC-MS analysis and antioxidant activity of the oil in broken spore of Dictyophora echinovolvata. Nat Prod Res Dev 30:239–245

    Google Scholar 

  • Lin H, Xiong GH, He JG, Zhang XY (2018b) Optimization of ultrasonic assisted extraction of phenolic compounds from Lactarius hatsudake Tanaka. Food Mach 34:161–215

    Google Scholar 

  • Liu B (1984) The Chinese medical fungi. Shanxi People’s Press, Taiyuan, pp 1–228

    Google Scholar 

  • Liu J, Bau T (2018) New species and new records in the genus Conocybe (Bolbitaceae) from China. Phytotaxa 357:261–274

    Article  Google Scholar 

  • Liu XT, Winkler AL, Schwan WR, Volk TJ, Rott MA, Monte A (2010) Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis. Planta Med 76:182–185

    Article  CAS  PubMed  Google Scholar 

  • Liu CJ, Chiang CC, Chiang BH (2012a) The elicited two-stage submerged cultivation of Antrodia cinnamomea for enhancing triterpenoids production and antitumor activity. Biochem Eng J 64:48–54

    Article  CAS  Google Scholar 

  • Liu Y, Li YF, Zheng KY, Fei XF (2012b) Antitumor active protein-containing glycans from the body of Ganoderma tsugae. Chem Res Chin Univ 28:449–453

    CAS  Google Scholar 

  • Liu YN, Chen YP, Wang LH, Zhao ZJ, Liu WJ, Wang Z, Deng YY, Ma L (2012c) Effect of Cordyceps sobolifera mycelium on some protein and mRNA expressions such as α-SMA in tubular epithelial cells exposed to TGF-β. Chin J Integ Trad West Nephr 13:1046–1049

    CAS  Google Scholar 

  • Liu G, She SQ, Gao WS, Kang DZ (2013a) Five kinds of fungi in Changbai mountain crude extract of antioxidant research. J Med Sci Yanbian Univ 36:16–21

    Google Scholar 

  • Liu J, Jia L, Kan J, Jin CH (2013b) In vitro and in vivo antioxidant activity of ethanolic extract of white button mushroom (Agaricus bisporus). Food Chem Toxicol 51:310–316

    Article  CAS