Abstracts
Objective
To develop a predictive model for late stillbirth among women with hypertensive disorders of pregnancy (HDP) in low- and middle-income countries.
Materials and Methods
Study was part of the WHO newborn birth defect (NBBD) project and included all stillbirths occurring in the facility from November 2015 to December 2020. The age and parity matched subjects with HDP having live birth were taken as controls. All significant predictors were analyzed and a predictive model was developed.
Results
Out of 69,007 deliveries, 1691(24.5/1000) were stillborn. HDP was seen in (390/1691, 23.0%), in 265/390 (67.4%) cases it occurred at or after 28 weeks of gestation and were included as cases. On comparing the cases with controls, the significant factors were estimated fetal weight less than 2000 gms (P < 0.001, OR 10.3), poor antenatal care (p < 0.001, OR–5.9), family history of hypertension (p < 0.018, OR-4.4) and the presence of gestational hypertension (p = 0.001, OR 2.2). The predictive model had sensitivity and specificity of 80.3% and 70.03%, respectively, the receiver operating curve showed the area under the curve(AUC) in the range of good prediction (0.846).
Conclusion
The predictive model could play a potential role in stillbirth prevention in women with HDP in low- and middle-income countries.
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Acknowledgements
The Project has been funded by WHO SEARO. We are thankful to Mr. Yogember Negi for his contribution as a computer data operator of the project.
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Manisha Kumar, Professor, Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi. V Ravi, Assistant Professor, Department of Statistics, Lady Sri Ram College, New Delhi. Deepika Meena, Associate Professor, Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi. Kanika Chopra, Assistant Professor , Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi. Shilpi Nain, Professor, Department of Obstetrics and Gynecology, Lady Hardinge Medical College, New Delhi. Manju Puri, Director Professor and HOD, Department of Obstetrics and gynecology, Lady Hardinge Medical College, New Delhi.
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Kumar, M., Ravi, V., Meena, D. et al. Predictive Model for Late Stillbirth Among Antenatal Hypertensive Women. J Obstet Gynecol India 72 (Suppl 1), 96–101 (2022). https://doi.org/10.1007/s13224-021-01561-3
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DOI: https://doi.org/10.1007/s13224-021-01561-3