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High Frequency of Malignant Transformations on Ovarian Mature Teratomas at a Single University Hospital, Jakarta, Indonesia (2015–2018)

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Abbreviations

MT:

Mature teratoma

FIGO:

International Federation of Gynecology and Obstetrics

CT-SCAN:

Computed tomography scan

MRI:

Magnetic resonance imaging

ECOG:

Eastern Cooperative Oncology Group

CP:

Carboplatin and paclitaxel

BEP:

Bleomycin, etoposide, and platinum

FOLFOX:

Folinic acid, 5-fluorouracil, and oxaliplatin

References

  1. Tavassoli F, Devilee P. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: IARC Press (International Agency for Research of Cancer), 2003.

  2. Duffy S, Day EK, Bryson G, Millan D, Lindsay R. Malignant tumours arising within mature cystic teratomas of the ovary: prevalence and clinical outcomes. Eur J Obstet Gynecol Reprod Biol. 2018;221:198–9. https://doi.org/10.1016/j.ejogrb.2017.12.022.

    CAS  Article  PubMed  Google Scholar 

  3. Oranratanaphan S, Khemapech N. Characteristics and treatment outcomes of patients with malignant transformation arising from mature cystic teratoma of the ovary: experience at a single institution. Asian Pac J Cancer Prev. 2013;14(8):4693–7. https://doi.org/10.7314/apjcp.2013.14.8.4693.

    Article  PubMed  Google Scholar 

  4. Yoshikawa N, Teshigawara T, Ikeda Y, Nishino K. Fertility-sparing surgery of malignant transformation arising from mature cystic teratoma of the ovary. Oncotarget. 2018;9(44):27564–73.

    Article  Google Scholar 

  5. Black J, Roque D, Pasternak M, et al. A series of malignant ovarian cancers arising from within a mature cystic teratoma. Int J Gynecol Cancer. 2015;25(5):792–7. https://doi.org/10.1097/igc.0000000000000431.

    Article  PubMed  Google Scholar 

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Funding

None. All the research and writing was self-funded from the authors.

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Authors and Affiliations

Authors

Contributions

All authors have read and approved the manuscript. TWU interpreted the data regarding the malignant transformation of the mature teratoma and writing the manuscript; HMARP performed the data collection, co-author the manuscript, and corresponding author; TH performed the histological examination and pointed out the importance of the histological results.

Corresponding author

Correspondence to Henny Meitri Andrie Rachmasari Putri.

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Conflict of interest

No conflict of interest.

Ethics Approval

Ethics approval was obtained from the Ethics committee of the Faculty of Medicine, University of Indonesia (attached ethical approval letter); No. KET-498/UN2.F1/ETIK/PPM.00.02/2019 and Protocol Number: 19–05-0531.

Availability of Data and Material

Data and materials were available in the Case Report Form of Dr. Cipto Mangunkusumo Hospital.

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Tofan Widya Utami: Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Henny Meitri Andrie Rachmasari Putri: Gyn-oncologist, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Indonesia Army Hospital (RSPAD Gatot Soebroto), Jakarta, Indonesia. Tantri Hellyanti: Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Pathological Anatomy, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

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Utami, T.W., Putri, H.M.A.R. & Hellyanti, T. High Frequency of Malignant Transformations on Ovarian Mature Teratomas at a Single University Hospital, Jakarta, Indonesia (2015–2018). J Obstet Gynecol India 72, 270–273 (2022). https://doi.org/10.1007/s13224-020-01392-8

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  • DOI: https://doi.org/10.1007/s13224-020-01392-8