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The Journal of Obstetrics and Gynecology of India

, Volume 68, Issue 6, pp 440–446 | Cite as

Pregnancy Check Point for Diagnosis of CKD in Developing Countries

  • A. Kaul
  • D. Bhaduaria
  • M. Pradhan
  • R. K. Sharma
  • N. Prasad
  • A. Gupta
Original Article
  • 23 Downloads

Abstract

Objective

Evidences suggest that females with CKD are associated with high risk of maternal and fetal complications. Early referral in CKD with pregnancy for specialist care may prove useful for maternal and fetal outcome.

Methods

Study looked for assessment of impact of CKD detection at the time of pregnancy and its impact on fetal and maternal outcome.

Results

A total of 465 females were retrospectively evaluated for renal status during their pregnancies, 172 females were unaware about their renal illness at the time of pregnancy, while 208 females were under regular obstetrical and nephrological follow-up during their pregnancy. 44.1% of these females in both groups had GFR < 60 ml/min. Preeclampsia was observed in 17.6% of planned pregnancies, while it was observed in 47.5% of unplanned pregnancies. Worsening of renal failure during and following pregnancy was observed among all stages of CKD, and there was greater decline in GRF with progression to ESRD earlier during or after pregnancy among unplanned pregnancies. Planned pregnancy group had better fetal outcome. Low birth babies weighing < 2500 g in unplanned group were much higher than in planned pregnancies.

Conclusions

Chronic kidney disease is often clinically silent until renal impairment is advanced. Pregnancy can be a check point for detection of renal disease and managed appropriately for better maternal and fetal outcome.

Keywords

Pregnancy Chronic kidney disease Maternal outcome Foetal outcome Dialysis dependancy 

Notes

Compliance with ethical standards

Conflict of interest

There is no conflict of interest between any of the authors.

Ethical approval

The paper is as per ethical standards approved by our own ethical committee in our institute.

Research involving human patients/animals rights

This research focussed on the human patients.

Informed consent

The informed consent was obtained from all the patients enrolled in the study.

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Copyright information

© Federation of Obstetric & Gynecological Societies of India 2017

Authors and Affiliations

  • A. Kaul
    • 1
  • D. Bhaduaria
    • 1
  • M. Pradhan
    • 2
  • R. K. Sharma
    • 1
  • N. Prasad
    • 1
  • A. Gupta
    • 1
  1. 1.Department of NephrologySanjay Gandhi Post Graduate Institute of Medical SciencesLucknowIndia
  2. 2.Department of Maternal and Foetal MedicineSanjay Gandhi Post Graduate Institute of Medical SciencesLucknowIndia

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