The Journal of Obstetrics and Gynecology of India

, Volume 67, Issue 6, pp 393–399 | Cite as

Down Syndrome Screening in India: Are We There Yet?

  • K. Manikandan
  • Suresh Seshadri
Invited Review Article


Down syndrome is the most common cause of intellectual disability among live born children and is amenable to prenatal detection. Screening for Down syndrome on a population basis requires a thorough understanding of the principles involved in the screening tests. We discuss the rationale behind the commonly available screening tests and the Indian scenario in this setting.


Down syndrome Prenatal screening Combined screening test Quadruple screening test Indian scenario 


Compliance with Ethical Standards

Conflict of interest

SS is Honorary Clinical Director of PerkinElmer Laboratory, Chennai. KM declares that he has no conflict of interest.

Human and Animals Rights

The authors declare that no human research participants or animals were involved in composing this invited review article.

Informed Consent

The authors declare that informed consent was not required for this invited review article as no human research participants were involved.


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Copyright information

© Federation of Obstetric & Gynecological Societies of India 2017

Authors and Affiliations

  1. 1.Department of Fetal MedicineMediscan SystemsChennaiIndia
  2. 2.Fetal Care Research FoundationChennaiIndia

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