Abstract
Purpose
This study aimed to determine whether MSAF is associated with endometritis after delivery.
Methods
This cohort study was conducted from 2012 to 2013 in Kosar Hospital of Qazvin, Iran. All women with cesarean delivery (1239 women) beyond 37 weeks of gestational age participated in the study. Data were collected on rates of endomyometritis, quality of amniotic fluid and were analyzed with bivariate and multivariate statistics. Probability values of <.05 were considered statistically significant.
Results
We found that among 1239 women with cesarean delivery at term 2.34 % were diagnosed with endometritis. Compared with deliveries with clear amniotic fluid, those with MSAF had higher rates of endomyometritis (1.5 vs 3.2 %, P < .04).
Conclusion
We found that the presence of MSAF is associated with puerperal infection even when being controlled for confounders.
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References
Unsworth J, Vause S. Meconium in labour. Obstet Gynecol Reprod Med. 2010;20(10):289–94.
Scott H, Walker M, Gruslin A. Significance of meconium-stained amniotic fluid in the preterm population. J Perinatol. 2001;21(3):174–7.
Boonprasert K, Painchkul P. The association between meconium—stained amniotic fluid and chorioamnionitis or endometritis. J Med Thai. 2007;90(3):442–7.
Miller PW, Coen RW, Benirschke K. Dating the time interval from meconium passage to birth. Obstet Gynecol. 1985;66(4):459–62.
Cunningham FG, Leveno KJ, Bloom SL, et al. Williams obstetrics. 23rd ed. New York: McGraw-Hill; 2010.
Wiswell TE, Tuggle JM, Turner BS. Meconium aspiration syndrome: Have we made a difference? Pediatrics. 1990;85:715–21.
Rahman S, Unsworth J, Vause S. Meconium in labour. Obstet Gynecol Reprod Med. 2013;28:247–52.
Susan H, Aaron B, Thomas J. Meconium-stained amniotic fluid is associated with puerperal infections. Am J Obstet Gynecol. 2003;189(3):746–50.
Kabiru W, Raynor BD. Obstetric outcomes associated with increase in BMI category during pregnancy. Am J Obstet Gynecol. 2004;191(3):928–32.
Casey BM, Cox SM. Chorioamnionitis and endomyometritis. Infect Dis Clin North Am. 1997;11:203–22.
Usta IM, Sibai BM, Mercer BM. Use of maternal plasma level of zinc-coproporphyrin in the prediction of intrauterine passage of meconium: a pilot study. J Matern Fetal Med. 2000;9:201–3.
Piper JM, Newton ER, Berkus MD, et al. Meconium: a marker for peripartum infection. Obstet Gynecol. 1998;91:741–5.
Siriwachirachai T, Sangkomkamhang US, Lumbiganon P, et al. Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections (review). This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2014, Issue 11.
Rahimi Sharbaf F, Davari Tanha F, Niromansh Sh. Meconium-stained amniotic fluid as an independent risk factor for fever and postpartum infection in term pregnancy. Tehran Univ Med J. 2008;66(3):203–7.
Mostaghel N, Abbasi N, Zamani A. Meconium—stained amniotic fluid and puerperal infection. Pejouhesh. 2008;32(3):189–92.
Salari Z, Ranjbar M, Ranjbar M. The comparison of maternal endometritis in meconium—stained amniotic fluid and clear amniotic fluid. J Kerman Univ Med Sci. 2007;14(3):203–9.
Jazayeri A, Jazayeri MK, Sahinler M. Is meconium passage a risk factor for maternal infection in termpregnancies. Obstet Gynecol. 2002;99(4):548–52.
Piper JM, Netwon ER, Berkus MD. Meconium: a marker for peripartum infection. Obstet Gynecol. 1998;91:741–5.
Mostaghel N, Abbasi N, Zamani A. Meconium amniotic fluid is associated with puerperal infections. Pazhohesh Med. 2008;32(3):189–92.
Balchin I, Whittaker JC, Lamont RF, et al. Maternal and fetal characteristics associated with meconium—stained amniotic fluid. Obstet Gynecol. 2011;117(4):828–35.
Sedaghatian M, Othman L, Rashid N, Ramachandran P, et al. An 8-year study of meconium stained amniotic fluid in different ethnic groups. Kuwait Med J. 2004;36(4):266.
Satomi M, Hiraizumi Y, Suzuki Sh. Perinatal outcomes associated with meconium-stained amniotic fluid in Japanese singleton pregnancies. OJOG. 2011;1:42–6.
Suzuki S. Post-term pregnancy as a risk factor for intrapartum fetal distress. J Perinat Med. 2009;37:420–1.
Zarkesh M, Asgharnia M, Faraji R, et al. Maternal risk factors and neonatal complications in term pregnancies with meconium stained amniotic fluid. ZUMS J. 2013;21(87):94–102.
Gulmezolgu AM, Crowther CA, Middleton P. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database Syst Rev. 2006;4:pub2.
Acknowledgments
This study is a funded research project which was approved at the Faculty of Nursing and Midwifery. We would like to thank all people who helped us to conduct this study.
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The research proposal of this study has been reviewed by the Medical Research Ethical Committee of the Qazvin University of Medical Science, and there is no conflict with ethical consideration date: January 15, 2012. The authors of this paper have not declared any conflicts of interest.
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Hamideh Pakniat is Assistant Professor in Department of Obstetric and Gynecology at School of Medical, Qazvin University of Medical Science; Fatemeh Mohammadi is Assistant Professor in Gerontology, Department of Midwifery at School of Nursing and Midwifery, Qazvin University of Medical Sciences; Fatemeh Ranjkesh is Instructor in Faculty of Nursing and Midwifery, Department of Midwifery, School of Nursing and Midwifery, Qazvin University of Medical Sciences.
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Pakniat, H., Mohammadi, F. & Ranjkesh, F. Meconium Amniotic Fluid is Associated with Endomyometritis. J Obstet Gynecol India 66 (Suppl 1), 136–140 (2016). https://doi.org/10.1007/s13224-015-0828-0
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DOI: https://doi.org/10.1007/s13224-015-0828-0