Skip to main content
Log in

Meconium Amniotic Fluid is Associated with Endomyometritis

  • Original Article
  • Published:
The Journal of Obstetrics and Gynecology of India Aims and scope Submit manuscript

Abstract

Purpose

This study aimed to determine whether MSAF is associated with endometritis after delivery.

Methods

This cohort study was conducted from 2012 to 2013 in Kosar Hospital of Qazvin, Iran. All women with cesarean delivery (1239 women) beyond 37 weeks of gestational age participated in the study. Data were collected on rates of endomyometritis, quality of amniotic fluid and were analyzed with bivariate and multivariate statistics. Probability values of <.05 were considered statistically significant.

Results

We found that among 1239 women with cesarean delivery at term 2.34 % were diagnosed with endometritis. Compared with deliveries with clear amniotic fluid, those with MSAF had higher rates of endomyometritis (1.5 vs 3.2 %, P < .04).

Conclusion

We found that the presence of MSAF is associated with puerperal infection even when being controlled for confounders.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Unsworth J, Vause S. Meconium in labour. Obstet Gynecol Reprod Med. 2010;20(10):289–94.

    Article  Google Scholar 

  2. Scott H, Walker M, Gruslin A. Significance of meconium-stained amniotic fluid in the preterm population. J Perinatol. 2001;21(3):174–7.

    Article  CAS  PubMed  Google Scholar 

  3. Boonprasert K, Painchkul P. The association between meconium—stained amniotic fluid and chorioamnionitis or endometritis. J Med Thai. 2007;90(3):442–7.

    Google Scholar 

  4. Miller PW, Coen RW, Benirschke K. Dating the time interval from meconium passage to birth. Obstet Gynecol. 1985;66(4):459–62.

    CAS  PubMed  Google Scholar 

  5. Cunningham FG, Leveno KJ, Bloom SL, et al. Williams obstetrics. 23rd ed. New York: McGraw-Hill; 2010.

    Google Scholar 

  6. Wiswell TE, Tuggle JM, Turner BS. Meconium aspiration syndrome: Have we made a difference? Pediatrics. 1990;85:715–21.

    CAS  PubMed  Google Scholar 

  7. Rahman S, Unsworth J, Vause S. Meconium in labour. Obstet Gynecol Reprod Med. 2013;28:247–52.

    Article  Google Scholar 

  8. Susan H, Aaron B, Thomas J. Meconium-stained amniotic fluid is associated with puerperal infections. Am J Obstet Gynecol. 2003;189(3):746–50.

    Article  Google Scholar 

  9. Kabiru W, Raynor BD. Obstetric outcomes associated with increase in BMI category during pregnancy. Am J Obstet Gynecol. 2004;191(3):928–32.

    Article  PubMed  Google Scholar 

  10. Casey BM, Cox SM. Chorioamnionitis and endomyometritis. Infect Dis Clin North Am. 1997;11:203–22.

    Article  CAS  PubMed  Google Scholar 

  11. Usta IM, Sibai BM, Mercer BM. Use of maternal plasma level of zinc-coproporphyrin in the prediction of intrauterine passage of meconium: a pilot study. J Matern Fetal Med. 2000;9:201–3.

    Article  CAS  PubMed  Google Scholar 

  12. Piper JM, Newton ER, Berkus MD, et al. Meconium: a marker for peripartum infection. Obstet Gynecol. 1998;91:741–5.

    CAS  PubMed  Google Scholar 

  13. Siriwachirachai T, Sangkomkamhang US, Lumbiganon P, et al. Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections (review). This is a reprint of a Cochrane review, prepared and maintained by The Cochrane Collaboration and published in The Cochrane Library 2014, Issue 11.

  14. Rahimi Sharbaf F, Davari Tanha F, Niromansh Sh. Meconium-stained amniotic fluid as an independent risk factor for fever and postpartum infection in term pregnancy. Tehran Univ Med J. 2008;66(3):203–7.

    Google Scholar 

  15. Mostaghel N, Abbasi N, Zamani A. Meconium—stained amniotic fluid and puerperal infection. Pejouhesh. 2008;32(3):189–92.

    Google Scholar 

  16. Salari Z, Ranjbar M, Ranjbar M. The comparison of maternal endometritis in meconium—stained amniotic fluid and clear amniotic fluid. J Kerman Univ Med Sci. 2007;14(3):203–9.

    Google Scholar 

  17. Jazayeri A, Jazayeri MK, Sahinler M. Is meconium passage a risk factor for maternal infection in termpregnancies. Obstet Gynecol. 2002;99(4):548–52.

    PubMed  Google Scholar 

  18. Piper JM, Netwon ER, Berkus MD. Meconium: a marker for peripartum infection. Obstet Gynecol. 1998;91:741–5.

    CAS  PubMed  Google Scholar 

  19. Mostaghel N, Abbasi N, Zamani A. Meconium amniotic fluid is associated with puerperal infections. Pazhohesh Med. 2008;32(3):189–92.

    Google Scholar 

  20. Balchin I, Whittaker JC, Lamont RF, et al. Maternal and fetal characteristics associated with meconium—stained amniotic fluid. Obstet Gynecol. 2011;117(4):828–35.

    Article  PubMed  Google Scholar 

  21. Sedaghatian M, Othman L, Rashid N, Ramachandran P, et al. An 8-year study of meconium stained amniotic fluid in different ethnic groups. Kuwait Med J. 2004;36(4):266.

    Google Scholar 

  22. Satomi M, Hiraizumi Y, Suzuki Sh. Perinatal outcomes associated with meconium-stained amniotic fluid in Japanese singleton pregnancies. OJOG. 2011;1:42–6.

    Article  Google Scholar 

  23. Suzuki S. Post-term pregnancy as a risk factor for intrapartum fetal distress. J Perinat Med. 2009;37:420–1.

    PubMed  Google Scholar 

  24. Zarkesh M, Asgharnia M, Faraji R, et al. Maternal risk factors and neonatal complications in term pregnancies with meconium stained amniotic fluid. ZUMS J. 2013;21(87):94–102.

    Google Scholar 

  25. Gulmezolgu AM, Crowther CA, Middleton P. Induction of labour for improving birth outcomes for women at or beyond term. Cochrane Database Syst Rev. 2006;4:pub2.

    Google Scholar 

Download references

Acknowledgments

This study is a funded research project which was approved at the Faculty of Nursing and Midwifery. We would like to thank all people who helped us to conduct this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fatemeh Ranjkesh.

Ethics declarations

Conflict of interest

The research proposal of this study has been reviewed by the Medical Research Ethical Committee of the Qazvin University of Medical Science, and there is no conflict with ethical consideration date: January 15, 2012. The authors of this paper have not declared any conflicts of interest.

Additional information

Hamideh Pakniat is Assistant Professor in Department of Obstetric and Gynecology at School of Medical, Qazvin University of Medical Science; Fatemeh Mohammadi is Assistant Professor in Gerontology, Department of Midwifery at School of Nursing and Midwifery, Qazvin University of Medical Sciences; Fatemeh Ranjkesh is Instructor in Faculty of Nursing and Midwifery, Department of Midwifery, School of Nursing and Midwifery, Qazvin University of Medical Sciences.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pakniat, H., Mohammadi, F. & Ranjkesh, F. Meconium Amniotic Fluid is Associated with Endomyometritis. J Obstet Gynecol India 66 (Suppl 1), 136–140 (2016). https://doi.org/10.1007/s13224-015-0828-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13224-015-0828-0

Keywords

Navigation