Abstract
Objective
Early detection of changes in cardiovascular echocardiographic systolic parameters and their comparison with normotensives women.
Methods
This was a hospital-based prospective case–control study carried out in Department of Obstetrics and Gynaecology in S.M.S Medical College, Jaipur, during the period from February 2013 to December 2014. In total, 100 women were enrolled in the study after applying inclusion and exclusion criteria. All women underwent two-dimensional echocardiography at rest. Cardiac systolic parameters were recorded and studied.
Results
Mean LVEDV in the PIH group was 75.71 ± 4.8 versus 71.08 ± 5.6 ml in the control group, and the difference was statistically significant. Mean stroke volume was higher in the PIH group as compared to the control group, and the difference was statistically significant (59.83 ± 7.4 vs. 52.48 ± 6.4 ml/min). Mean aortic root diameter in the PIH group was 2.188 ± 1.04 cm as compared to the 1.866 ± 1.06 cm in the control group which was statistically significant. Mean left ventricular outflow tract diameter was slightly higher in the PIH group as compared to the controls although the P value was not significant (2.37 ± 1.06 and 1.99 ± 1.08 cm). Mean total vascular resistance was found to be higher in the PIH group as compared to the controls, and the difference was statistically significant (1389 ± 57.04 vs. 1286 ± 45.01 dynes/sec/cm−5).
Conclusion
Systolic parameters get worsened in pre-eclamptics. Early detection of change in these parameters could help to identify high-risk women who are prone to develop cardiovascular morbidity in later life.
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Neha Jain, Asha Verma and Lata Rajoria declared that they have no conflict of interest.
Ethical standards
Studies with human subjects include the following statement: all procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5).
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Informed consent was obtained from all patients included in the study.
Additional information
Jain Neha is final-year resident in Department of Obstetrics and Gynaecology at S.M.S Medical College Asha Verma is Professor in Department of Obstetrics and Gynaecology at S.M.S Medical College Lata Rajoria is Professor and HOD in Department of Obstetrics and Gynaecology at S.M.S Medical College.
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Jain, N., Verma, A. & Rajoria, L. Evaluation of Echocardiographic Systolic Parameters in Pre-Eclamptics and Normotensives Women. J Obstet Gynecol India 66 (Suppl 1), 187–191 (2016). https://doi.org/10.1007/s13224-015-0823-5
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DOI: https://doi.org/10.1007/s13224-015-0823-5