Skip to main content
SpringerLink
Log in

Single-Step First Trimester Screening “Sooner the Better”

  • Original Article
  • Published:
The Journal of Obstetrics and Gynecology of India Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the role of single-step universal screening in first trimester and its effectiveness.

Materials and methods

Three thousand women attending antenatal clinic of Pt JNM Medical College, Raipur, were screened with 75 gm OGTT in their first trimester irrespective of their last meal, and those who were screened negative were again subjected to OGTT at 24–28 weeks. The women were followed throughout pregnancy till delivery. Any maternal or perinatal complications were noted.

Result

Overall incidence of GDM was 5.2 %. About 61.54 % women screened positive in first trimester. At 24–28 weeks, 38.46 % women were diagnosed with GDM. Women diagnosed in first trimester showed significantly low incidence of cesarean section rate (20.83 %), PIH (2.08 %), and macrosomia (14.44 %), in comparison to women diagnosed later in pregnancy.

Conclusion

The role of first trimester screening was found effective in reducing adverse maternal and perinatal outcomes in GDM.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. International Diabetes Federation. Policy briefing. Diabetes in pregnancy: protecting maternal health. Brussels: IDF.; 2011.

    Google Scholar 

  2. Kayal A, Anjana RM, Mohan V. Gestational diabetes—an update from India. Diabetes Voice. 2013;58(2):30–4.

    Google Scholar 

  3. Wahi P, Dogra V, Jandial K. Prevalence of gestational diabetes mellitus GDM and its outcomes in Jammu Region. JAPI. 2011;59:227–30.

    PubMed  Google Scholar 

  4. Vambergue A, Fajarde I. Consequences of gestational and pre-gestational diabetes on placental function and birth weight. World J Diabetes. 2011;2(11):196–203.

    PubMed  PubMed Central  Google Scholar 

  5. Rajput R, Yadav Y, Nanda S, et al. Prevalence of gestational diabetes mellitus & associated risk factors at a tertiary care hospital in Haryana. Indian J Med Res. 2013;137:728–33.

    PubMed  PubMed Central  Google Scholar 

  6. Anjana RM, Pradeepa R, Deepa M, et al. ICMR-INDIAB Collaborative study group, Prevalence of diabetes and prediabetes (Impaired fasting glucose and/or impaired glucose tolerance) in urban and rural India phase 1 result of Indian council of Medical Research-INdiaDIABates (ICMR-INDIAB) study. Diabetologia. 2011;54:3022–7.

    Article  CAS  PubMed  Google Scholar 

  7. Plasencia W, Garcia R, Pereira S, et al. Criteria for screening and diagnosis of gestational diabetes mellitus in the first trimester of pregnancy. Fetal Diagn Ther. 2011;30:108–15.

    Article  PubMed  Google Scholar 

  8. Seshiah V, Banerjee S, Balaji V, et al. Consensus evidence-based guidelines for management of gestational diabetes mellitus in India. Suppl JAPI. 2014;62:55–62.

    CAS  PubMed  Google Scholar 

  9. International Association of Diabetes and Pregnancy Study Groups. Recommendations on the diagnosis and classification of Hyperglycemia in pregnancy. Diabetes Care. 2010;33:3.

    Article  Google Scholar 

  10. WHO. Guidelines diagnostic criteria and classification of hyperglycemia first detected in pregnancy. 2013.

  11. NICE. Guidelines diabetes in pregnancy: management of diabetes and its complications from preconception to postnatal period nic.org.uk/guidence/ng3, 25 Feb 2015.

  12. Huynh J, Ratnaik S, Bartalotta C. Challenging the glucose challenge test. Aust N Z J Obstet Gynarcol. 2011;51:22–5.

    Article  Google Scholar 

  13. Savvidou M, Nelson MS, Makgoba M, et al. First—trimester prediction of diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures. Diabetes. 2010;59(12):3017–22.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Black MH, Sacks DA, Xiang AH, et al. Clinical outcome of pregnancies complicated by mild gestational diabetes differ by combinations of abnormal oral glucose tolerance test values. Diabetes Care. 2010;33(12):2524–30.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Landon MB, Mele L, Spong CY, et al. The relationship between maternal glycemia and perinatal outcome. Am Coll Obstet Gynecol. 2011;117:218–24.

    Article  CAS  Google Scholar 

  16. O’Sullivan EP, Avalos G, O’Reilly M, et al. Atlantic diabetes in pregnancy (DIP); the prevalence and outcomes of gestational diabetes mellitus using new diagnostic criteria. Diabetologia. 2011;54(7):1670–5.

    Article  PubMed  Google Scholar 

  17. Falavigna M, Prestes I, Schmidt MI, et al. Impact of gestational diabetes mellitus screening strategies on perinatal outcomes: a simulation study. Diabetes Res Clin Pract. 2013;99(3):358–65.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Obstetrics & Gynaecology, Pt. J.N.M. Medical College, E-8, Shankar Nagar, Raipur, Chhattisgarh, India

    Abha Singh

  2. Department of Obstetrics & Gynaecology, Pt. J.N.M. Medical College, A-12, Maruti Residency, Amlidih, Raipur, Chhattisgarh, India

    Avinashi Kujur

Authors
  1. Abha Singh
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Avinashi Kujur
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Avinashi Kujur.

Ethics declarations

Conflict of interest

Abha Singh and Avinashi declare they have no conflict of interest.

Ethical Approval

As this was prospective observational study, not an interventional or case–control study, informed consent with human subjects for being included in the study was not necessary; however, all procedures followed were in accordance with ethical standard of the responsible committee on human experiments (institutional and international) and with the Helsinki Declaration of 1975, as revised in 2008(5).

Additional information

Dr. Abha Singh is a Director, Professor, & HOD in the Department of Obstetrics & Gynaecology at Pt. J.N.M. Medical College. Dr. Avinashi Kujur is an Assistant Professor in the Department of Obstetrics & Gynaecology at Pt. J.N.M. Medical College.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Singh, A., Kujur, A. Single-Step First Trimester Screening “Sooner the Better”. J Obstet Gynecol India 66 (Suppl 1), 77–81 (2016). https://doi.org/10.1007/s13224-015-0785-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13224-015-0785-7

Keywords

Search

Navigation