Comparison of Diagnostic Efficacy of Umbilical Artery and Middle Cerebral Artery Waveform with Color Doppler Study for Detection of Intrauterine Growth Restriction
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Background and Objectives
Intrauterine growth restriction is associated with increased perinatal mortality and morbidity, possibly extending also in adult life, as compared to fetuses and newborns presenting characteristics of normal growth. The present study had been planned to measure the pulsatility index (PI) and resistive index of the middle cerebral artery with pulsatility and resistive index of the umbilical artery in predicting fetal growth restriction.
Materials and Methods
A total of 60 pregnant women with a clinical history and grayscale-screened patients were taken for Doppler analysis, and a final comparison of accuracy of Doppler indices was done with perinatal outcome.
The statistical analysis was done using the Statistical Package for Social Sciences version 15.0 statistical analysis software. The values were represented in number (%) and mean ± SD.
Observation and Results
The umbilical artery PI had maximum sensitivity at the third visit (32–37 weeks) and maximum specificity also at the third visit (32–37 weeks). The umbilical artery resistive index had maximum sensitivity at the second visit (28–32 weeks) and maximum specificity at the third visit (32–37 weeks). The MCA PI had an overall diagnostic accuracy of 52.8 %.
The PI of the umbilical artery was more sensitive than the PI of the middle cerebral artery. Umbilical artery PI has the maximum overall diagnostic accuracy of 75 %.
KeywordsPulsatility index Resistive index Sensitivity Diagnostic accuracy Obstetrical Doppler
Middle cerebral artery
Intrauterine growth retardation
Positive predictive value
Negative predictive value
- 4.Gudmundsson S, Marsal K. Umbilical artery and uteroplacental blood flow velocity waveforms in normal pregnancy—a cross-sectional study. Eur J Obstet Gynaecol. 1988;67(4):347–54.Google Scholar
- 5.Dhand H, Kansal HK, Dave A. Middle cerebral artery doppler indices better predictor for fetal outcome in IUGR. J Obstet Gynecol India. 2011;61:166–71.Google Scholar
- 7.Narula H, Kapila AK, Mohi MK. Cerebral and umbilical arterial blood flow velocity in normal and growth retarded pregnancy. J Obstet Gynecol India. 2009;59(1):47–52.Google Scholar
- 10.Aali BS, Narooi S, Mojtabaean B, et al. Screening utility of umbilical artery Doppler indices in patients with preeclampsia. Iran J Reprod Med. 2010;8(4):167–72.Google Scholar