Comparison of Diagnostic Efficacy of Umbilical Artery and Middle Cerebral Artery Waveform with Color Doppler Study for Detection of Intrauterine Growth Restriction

  • Sachin Khanduri
  • Umesh C. Parashari
  • Shazia Bashir
  • Samarjit Bhadury
  • Anurag Bansal
Original Article


Background and Objectives

Intrauterine growth restriction is associated with increased perinatal mortality and morbidity, possibly extending also in adult life, as compared to fetuses and newborns presenting characteristics of normal growth. The present study had been planned to measure the pulsatility index (PI) and resistive index of the middle cerebral artery with pulsatility and resistive index of the umbilical artery in predicting fetal growth restriction.

Materials and Methods

A total of 60 pregnant women with a clinical history and grayscale-screened patients were taken for Doppler analysis, and a final comparison of accuracy of Doppler indices was done with perinatal outcome.

Statistical Analysis

The statistical analysis was done using the Statistical Package for Social Sciences version 15.0 statistical analysis software. The values were represented in number (%) and mean ± SD.

Observation and Results

The umbilical artery PI had maximum sensitivity at the third visit (32–37 weeks) and maximum specificity also at the third visit (32–37 weeks). The umbilical artery resistive index had maximum sensitivity at the second visit (28–32 weeks) and maximum specificity at the third visit (32–37 weeks). The MCA PI had an overall diagnostic accuracy of 52.8 %.


The PI of the umbilical artery was more sensitive than the PI of the middle cerebral artery. Umbilical artery PI has the maximum overall diagnostic accuracy of 75 %.


Pulsatility index Resistive index Sensitivity Diagnostic accuracy Obstetrical Doppler 



Middle cerebral artery


Umblical artery


Pulsatility index


Resistive index




Intrauterine growth retardation


Positive predictive value


Negative predictive value






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Copyright information

© Federation of Obstetric & Gynecological Societies of India 2013

Authors and Affiliations

  • Sachin Khanduri
    • 1
  • Umesh C. Parashari
    • 1
  • Shazia Bashir
    • 1
  • Samarjit Bhadury
    • 1
  • Anurag Bansal
    • 1
  1. 1.Department of RadiologyEra’s Lucknow Medical College and HospitalLucknowIndia

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