Abstract
The increasing use of synthetic polymers and their disposal has raised concern due to their adverse effects on the environment. Thus, other sustainable alternatives to synthetic plastics have been sought, such as polyhydroxyalkanoates (PHAs), which are promising microbial polyesters, mainly due to their compostable nature, biocompatibility, thermostability, and resilience, making this biopolymer acceptable in several applications in the global market. The large-scale production of PHAs by microorganisms is still limited by the high cost of production compared to conventional plastics. This review reports some strategies mentioned in the literature aimed at production and recovery, paving the way for the bio-based economy. For this, some aspects of PHAs are addressed, such as synthesis, production systems, process control using by-products from industries, and advances and challenges in the downstream. The bioplastics properties made them a prime candidate for food, pharmaceutical, and chemical industrial applications. With this paper, it is possible to see that biodegradable polymers are promising materials, mainly for reducing the pollution produced by polymers derived from petroleum.
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Data supporting the findings of this study are available from the corresponding author upon reasonable request.
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Acknowledgements
The authors thank URI Erechim, the National Council for Scientific and Technological Development—Brazil (CNPq), Coordination for the Improvement of Higher Education Personnel—Brazil (CAPES), and the Research Support Foundation of the State of Rio Grande do Sul (FAPERGS).
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This study was financed in part by the National Council for Scientific and Technological Development—Brazil (CNPq)—project number 431493/2018-9, the Coordination for the Improvement of Higher Education Personnel—Brazil (CAPES)—Finance Code 001, and the Research Support Foundation of the State of Rio Grande of Sul—Brazil (FAPERGS).
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de Melo, R.N., de Souza Hassemer, G., Steffens, J. et al. Recent updates to microbial production and recovery of polyhydroxyalkanoates. 3 Biotech 13, 204 (2023). https://doi.org/10.1007/s13205-023-03633-9
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DOI: https://doi.org/10.1007/s13205-023-03633-9