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Enhanced and sustainable pretreatment for bioconversion and extraction of resveratrol from peanut skin using ultrasound-assisted surfactant aqueous system with microbial consortia immobilized on cellulose

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Abstract

In this study, the ultrasound-assisted surfactant aqueous system coupled with microbial consortia immobilized by cellulose has been created as an enhanced and sustainable method for the bioconversion and extraction of resveratrol from peanut skin. Based on central composite design, and several single-factor experiments, we derived the optimal bioconversion and extraction system. Microbial consortia consist of Yeast CICC 1912, Aspergillus oryzae 3.951 and Aspergillus niger 3.3148 were chosen to be immobilized using cellulose. Other treatment conditions include concentration of surfactant as 3% (w/v), temperature as 30 °C, time as 36 h, ultrasonic power as 250 W and liquid to solid ratio as 25:1 mL/g. Under these conditions, we achieved a promising yield of resveratrol 96.58 μg/g, which is 4.02 folds compared to the untreated sample. This sustainable and green method not only enhanced the production of resveratrol but also improved the safety and reliability of the bioconversion and extraction process. Our novel method has shown great potential to realize large-scale bioconversion and extraction of bioactive compounds from plant waste.

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Acknowledgements

The authors gratefully acknowledge the financial supported by Special Fund of Natural Science Foundation of Heilongjiang province (H2018053), University Nursing Program for Young Scholars with Creative Talents in Helongjiang Province (UNPYSCT-2017214), Excellent young teacher support program from Heilongjiang University of Chinese Medicine, China Postdoctoral Science special Foundation (2018T110321), Postdoctoral fund of China (2016M591567), Postdoctoral fund of Heilongjiang province (LBH-Z15206), Special Fund of National Natural Science Foundation of China (31270618).

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Authors and Affiliations

  1. College of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, 150040, People’s Republic of China

    Shuang Jin, Mengmeng Gao, Bingyou Yang, Haixue Kuang, Bo Yang, Yupeng Cheng & Huiling Li

  2. Key Laboratory of Chinese Materia Medica, Ministry of Education, Harbin, 150040, People’s Republic of China

    Shuang Jin, Mengmeng Gao, Bingyou Yang, Haixue Kuang, Bo Yang, Yupeng Cheng & Huiling Li

  3. Department of Bioengineering, University of Illinois at Urbana–Champaign, Urbana, IL, USA

    Wentao Kong

  4. State Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin, 150040, People’s Republic of China

    Yujie Fu

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  1. Shuang Jin
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  2. Mengmeng Gao
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  3. Wentao Kong
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  4. Bingyou Yang
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  5. Haixue Kuang
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  6. Bo Yang
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  7. Yujie Fu
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  8. Yupeng Cheng
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  9. Huiling Li
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Correspondence to Shuang Jin, Bingyou Yang, Haixue Kuang, Bo Yang or Yujie Fu.

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Jin, S., Gao, M., Kong, W. et al. Enhanced and sustainable pretreatment for bioconversion and extraction of resveratrol from peanut skin using ultrasound-assisted surfactant aqueous system with microbial consortia immobilized on cellulose. 3 Biotech 10, 293 (2020). https://doi.org/10.1007/s13205-020-02287-1

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