Abstract
This study was to diagnose stroke patients based on the application of Fe2O3 super nanoparticles in magnetic resonance imaging (MRI) to explore the magnetic properties, colloidal stability, and particle electrical properties of Fe2O3 super nanoparticles, so that they could be better used in MRI contrast agents. In addition, the nursing management of the medical department was evaluated to enable stroke patients to recover better. The inpatients with acute ischemic stroke (AIS) in the Department of Neurology of Wuhan Third Hospital from September 2020 to April 2021 were selected and divided into a routine group and a control group. The Fe2O3 super nanoparticle magnetic solvent was prepared and mixed with contrast agent, and the MRI image was observed to inspect the brain ischemic lesions. The self-care situation and hospitalization expenses of patients were assessed, so as to evaluate the quality of nursing. The results suggested that the particles were 16 nm in diameter, and were the most stable when the electricity was at 16 V, so the ischemic focus of MRI could be obviously easy to observe. The score on self-care ability of patients in the control group was improved by 0.33, and that in the routine group was improved by 7.11 when they were discharged from the hospital, showing statistically obvious difference (P < 0.05). In addition, the use of Fe2O3 magnetic nanoparticles can identify hypoperfusion lesions and distinguish the ischemic core from the ischemic penumbra in a short time. While meeting the clinical needs, the Fe2O3 magnetic nanoparticles can provide quantitative hemodynamic information to better help diagnose lesions. At the same time, using day medical nursing management quality evaluation can better track the care of stroke patients and guide the formulation of individualized treatments, showing good potential in clinical application.
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The study and all the participants were reviewed and approved by Ethics Committee of Wuhan Third Hospital (NO. WHTH2020T053).
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Li, J., Hou, L. & Zhang, M. Diagnosis and treatment of stroke with Fe2O3 super nanoparticles and quality evaluation of nursing management in day medical department. Appl Nanosci 13, 3571–3578 (2023). https://doi.org/10.1007/s13204-022-02728-8
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DOI: https://doi.org/10.1007/s13204-022-02728-8