Abstract
Luminescent O, N-containing carbon nanoparticles (O, N-CNPs) were synthesized by the one-step method. Their surface chemistry was studied by TPD-MS, TGA, and 1H NMR. Different groups, carboxyl, imide, and amide groups, were found. The small (O, N)-CNPs dispersed in water have a high quantum yield of 0.26 with respect to quinine sulfate in 0.05 M sulfuric acid. We investigated the change in the fluorescence emission intensity using a titration of a colloidal solution of (O, N)-CNPs with unimolar solutions of KOH, HCl, or NaCl. The quenching efficiency strongly depends on the pH and is less dependent on the content of indifferent electrolytes. The small (O, N)-CNPs showed high fluorescence emission intensity in a neutral buffer in a Krebs solution. Besides, they showed a pronounced pH-dependent fluorescence quenching at acidic pH levels. These small (O, N)-CNPs are promising materials for biomedical applications as fluorescent probes with high acidic sensitivity because of high stability and high intensive fluorescence in a complex water matrix. With this aim, polymer hybrid hydrogels for wound dressings were modified with (O, N)-CNPs. Some of the obtained composites are potentially effective for fluorescence pH-sensitive testing and the screening monitoring of wound healing.
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Acknowledgements
Vladyslav V. Lisnyak and Gauhar Mussabek acknowledge financial support from the Ministry of Education and Science of the Republic of Kazakhstan, Grant No. AP08856579. Vladyslav V. Lisnyak is grateful for the partial support of the Ministry of Education and Science of Ukraine under the Grant of the Ministry of Education and Science of Ukraine for perspective development of a scientific direction "Mathematical sciences and natural sciences" at the Taras Shevchenko National University of Kyiv and the partial support of the Ministry of Education and Science of Ukraine under the Grant No. 0122U002023.
Funding
This research was funded by the Ministry of Education and Science of the Republic of Kazakhstan within project No. AP08856579. Vladyslav V. Lisnyak was partially supported by the Ministry of Education and Science of Ukraine as part of the funding of the perspective development of a scientific direction "Mathematical sciences and natural sciences" at the Taras Shevchenko National University of Kyiv and the Grant No. 0122U002023.
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Diyuk, N.V., Keda, T.Y., Zaderko, A.N. et al. Luminescent carbon nanoparticles immobilized in polymer hydrogels for pH sensing. Appl Nanosci 12, 2357–2365 (2022). https://doi.org/10.1007/s13204-022-02536-0
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DOI: https://doi.org/10.1007/s13204-022-02536-0