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Journal of Food Science and Technology

, Volume 53, Issue 7, pp 3104–3112 | Cite as

Sea fennel (Crithmum maritimum L.): phytochemical profile, antioxidative, cholinesterase inhibitory and vasodilatory activity

  • Ivana Generalić MekinićEmail author
  • Ivica Blažević
  • Ivana Mudnić
  • Franko Burčul
  • Mia Grga
  • Danijela Skroza
  • Iva Jerčić
  • Ivica Ljubenkov
  • Mladen Boban
  • Mladen Miloš
  • Višnja Katalinić
Original Article

Abstract

Sea fennel, a rediscovered star of the coastal cuisine, has been investigated for its phytochemical profile and biological potential. Sea fennel flowers, stems and leaves were analyzed for essential oils (EOs) isolated by hydrodistillation, as well as non-volatiles obtained by ethanolic extraction. Limonene were found to be a dominant compound in EOs and ethanolic extracts; ranging from 57.5–74.2 % and 0.7–8.1 mg/g dry plant material, respectively. In addition total phenolic content was determined for ethanolic extracts. All samples and their main phytochemicals were tested for various methods. EO and extract obtained from flowers were tested for vasodilatory activity on rat aortic rings. Antioxidant activity of EOs was extremely low in comparison to extracts, on the contrary to cholinesterase inhibition where EOs showed better activity than extracts. Flower extract and chlorogenic acid showed stronger vasodilators in comparison to EO and limonene. The obtained results point out the potential impact of the dominant compounds from EO and extract on the biological properties of the sea fennel.

Keywords

Chlorogenic acid Limonene Antioxidation Cholinesterase inhibition Vasodilatation 

Notes

Acknowledgments

This work has been fully supported by Croatian Science Foundation under the projects IP-2014-09-6897 and IP-2013-11-8652.

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Copyright information

© Association of Food Scientists & Technologists (India) 2016

Authors and Affiliations

  • Ivana Generalić Mekinić
    • 1
    Email author
  • Ivica Blažević
    • 2
  • Ivana Mudnić
    • 3
  • Franko Burčul
    • 4
  • Mia Grga
    • 1
  • Danijela Skroza
    • 1
  • Iva Jerčić
    • 3
  • Ivica Ljubenkov
    • 5
  • Mladen Boban
    • 3
  • Mladen Miloš
    • 4
  • Višnja Katalinić
    • 1
  1. 1.Department of Food Technology and Biotechnology, Faculty of Chemistry and TechnologyUniversity of SplitSplitCroatia
  2. 2.Department of Organic Chemistry, Faculty of Chemistry and TechnologyUniversity of SplitSplitCroatia
  3. 3.Department of Pharmacology, School of MedicineUniversity of SplitSplitCroatia
  4. 4.Department of Biochemistry, Faculty of Chemistry and TechnologyUniversity of SplitSplitCroatia
  5. 5.Department of Chemistry, Faculty of ScienceUniversity of SplitSplitCroatia

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