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Horse gram- an underutilized nutraceutical pulse crop: a review

Abstract

Horse gram is an underutilized pulse crop grown in wide range of adverse climatic conditions. It occupies an important place in human nutrition and has rich source of protein, minerals, and vitamins. Besides nutritional importance, it has been linked to reduced risk of various diseases due to presence of non-nutritive bioactive substances. These bioactive substances such as phytic acid, phenolic acid, fiber, enzymatic/proteinase inhibitors have significant metabolic and/or physiological effects. The importance of horse gram was well recognized by the folk/alternative/traditional medicine as a potential therapeutic agent to treat kidney stones, urinary diseases, piles, common cold, throat infection, fever etc. The inception of nutraceutical concept and increasing health consciousness the demand of nutraceutical and functional food is increased. In recent years, isolation and utilization of potential antioxidants from legumes including horse gram are increased as it decreases the risk of intestinal diseases, diabetes, coronary heart disease, prevention of dental caries etc. Keeping in view the increasing demand of food having nutraceutical values, the present review ascribed with recent scientific knowledge towards the possibilities of exploring the horse gram, as a source of food and nutraceuticals compounds.

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References

  1. Aaby K, Hvattum E, Skrede G (2004) Analysis of flavonoids and other phenolic compounds using high-performance liquid chromatography with coulometric array detection: relationship to antioxidant activity. J Agric Food Chem 52:4595–4603

  2. Acharya SN, Thomas JE (2007) Advances in medicinal plant research. Research Signpost, Kerala

  3. Achaya KT (1998) A historical dictionary of Indian food. Oxford University Press, Delhi

  4. Aiyer YN (1990) Horse gram. In: Aiyer YN (ed) Field crops of India, 7th edn. Bangalore Press, Banglore, pp 115–117

  5. Akin Ŏ, Temelli F, Kőseoğlu S (2012) Membrane applications in functional foods and nutraceuticals. Crit Rev Food Sci Nutr 52:347–371

  6. Alles MS, Hartemink R, Meyboom S, Harryvan JL, Van La ere K, Nagengast FM (1999) Effect of transgalactooligo-saccharides on the composition of the human intestinal microflora and on putative risk markers for colon cancer. Am J Clin Nutr 69:980–991

  7. Anderson JW, Bridge SR (1988) Dietary fiber content of selected foods. Am J Clin Nutr 47:440–447

  8. Anderson JW, Smith BM, Gustafson NJ (1994) Health benefits and practical aspects of high-fiber diets. Am J Clin Nutr 59:1242S–1247S

  9. Arinathan V, Mohan VR, De Britto AJ (2003) Chemical composition of certain tribal pulses in south India. Int J Food Sci Nutr 54:209–217

  10. Asp N-G, Van Amelsvoort JMM, Hautvast JGAJ (1996) Nutritional implications of resistant starch. Nutr Res Rev 9:1–31

  11. Bajpai RP, Dwivedi RK, Singh VK (1990) Performance of horsegram on different dates of sowing, phosphorus levels and intercropping. Indian J Pulses Res 3(2):159–162

  12. Barnes S, Boersma B, Patel R (2000) Isoflavonoids and chronic disease: mechanisms of action. Biofactors 12:209–215

  13. Bazzano L, He J, Ogden LG, Loria C, Vuputuri S, Myers L (2001) Legume consumption and risk of coronary heart disease in US men and women. Arch Intern Med 161:2573–2578

  14. Belem MAF (1999) Application of biotechnology in the product development of nutraceuticals in Canada. Trends Food Sci Tech 10(3):101–106

  15. Bhardwaj J, Yadav SK (2012) Comparative study on biochemical and antioxidant enzymes in a drought tolerant and sensitive variety of horse gram (Macrotyloma uniflorum) under drought stress. Am J Plant Physiol 7:17–29

  16. Blanca HL, Hsieh CC, Lumen BOD (2009) Lunacin and Bowman - Birk protease inhibitor (BBI) in US commercial soy foods. Food Chem 115:574–580

  17. Brand JC, Snow BJ, Nobhan GP, Truswell AS (1990) Plasma glucose and insulin responses to traditional Pima Indian meals. Am J Clin Nutr 51:416–420

  18. Bravo L (1999) Polyphenols: chemistry, dietary sources, metabolism and nutritional significance. Nutr Rev 56:317–333

  19. Bravo L, Siddhuraju P, Saura-Calixto F (1998) Effect of various processing methods on the in vitro starch digestibility and resistant starch content of Indian pulses. J Agr Food Chem 46:4667–4674

  20. Bravo L, Siddhuraju P, Saura-Calixto F (1999) Composition of underexploited Indian pulses. Comparison with common legumes. Food Chem 64:185–192

  21. Brink M (2006) Macrotyloma uniflorum (Lam.) Verdc. In: Brink M, Belay G (eds) PROTA 1: cereals and pulses/céréales et légumes secs. PROTA, Wageningen

  22. Brower V (1998) Nutraceuticals: poised for a healthy slice of the healthcare market? Nat Biotechnol 16:728–731

  23. Cardador-Martinez A, Loarca-Pina G, Oomah BD (2002) Antioxidant activity in common beans (Phaseolus vulgaris L.). J Agric Food Chem 50:6975–6980

  24. Chatterton DEW, Smithers G, Roupas P, Brodkorb A (2006) Bioactivity of beta-lactoglobulin and alpha-lactalbumin – Technological implications for processing. Int Dairy J 16(11):1229–1240

  25. Chel-Guerrero L, Perez-Flores V, Bentacur-Ancona D, Davila-Ortiz G (2002) Functional properties of flours and protein isolates from Phaseolus lunatus and Canavalia ensiformis seeds. J Agric Food Chem 50:584–591

  26. Chen YW, Huang SC, Shiau SYL, Lin JK (2005) Bowman –Birk inhibitor abates proteosome function and suppresses the proliferation of MCF7 breast cancer cells through accumulation of MAP kinase phosphatase-1. Carcinogenesis 26:1296–1306

  27. Chitra U, Vimala V, Singh U, Geervani P (1995) Variability in phytic acid content and protein digestibility of grain legumes. Plant Food Hum Nutr 47:163–172

  28. Chunekar KC, Pandey GS (1998) Bhavaprakash Nighantu (Indian Materia Medica) of Sri Bhavamisra (c. 1500–1600 AD). Chaukhamba Bharati Academy, Varanasi, 984 pp (reprint)

  29. Clemente A, Domoney C (2006) Biological significance of polymorphism in legume protease inhibitors from the Bowman – Birk family. Curr Protein Pep Sci 7:201–216

  30. Cook BG, Pengelly BC, Brown SD, Donnelly JL, Eagles DA, Franco MA, Hanson J, Mullen BF, Partridge IJ, Peters M, Schultze-Kraft R (2005) Tropical Forages: an interactive selection tool. [CD-ROM], CSIRO, DPI&F(Qld). CIAT and ILRI, Brisbane

  31. Cummings JH, Stephen AM (2007) Carbohydrate terminology and classification. Eur J Clin Nutr 61(Suppl. 1): 5–18

  32. Cummings JH, Bingham S, Heaton KW, Eastwood MA (1992) Faecal weight colon cancer risk, and dietary intake of non-starch polysaccharides (dietary fibre). Gasteroenterology 103:1783–1789

  33. Daniel S (2003) An investigation into the neuroprotective prospective of curcumin. Rhodes University. Electronic thesis collection TR 03–17

  34. Davis KR (1981) Effect of processing on composition of tetrahymena relative nutritive value on green and yellow peas, lentils and white pea beans. Cereal Chem 58:454–460

  35. Dilis V, Trichopoulou A (2009) Nutritional and health properties of pulses. Mediterr J Nutr Metab 1:149–157

  36. Dillard CJ, German JB (2000) Phytochemicals: nutraceuticals and human health. J Food Agric Sci 80(12):1744–1756

  37. Domoney C, Welham T, Sidebottom C (1993) Purification and characterization of Pisum seed trypsin inhibitor. J Exp Bot 261:701–709

  38. Dos Santos MD, Almeida MC, Lopes NP, de Souza GEP (2006) Evaluation of the anti-inflammatory, analgesic and antipyretic activity of the natural polyphenol chlorogenic acid. Biol Pharm Bull 29:2236–2240

  39. Duranti M (2006) Grain legume proteins and nutraceutical properties. Fitoterapia 77:67–82

  40. Duranti M, Gius C (1997) Legume seeds: protein content and nutritional value. Field Crop Res 53:31–45

  41. Eggum BO, Beames RM (1983) The nutritive value of seed protein. In: Gottschalk W, Müller HP (eds) Seed proteins: biochemistry, genetics, nutritive value. Kluwer Academic Publishers, The Hague, pp 499–531

  42. Frokiaer H, Horlyck L, Sorenson S, Sorenson H (1994) Immunoaffmity chromatography, purification and characterization of pea trypsin inhibitors. J Sci Food Agric 66:61–69

  43. Gary RL, Julius JD, Seymour K, James DL, Kennedy AR, Ware JH (2008) Bowman –Birk inhibitor concentrate: a novel therapeutic agent for patients with active ulcerative colitis. Digest Dis Sci 53:175–180

  44. Ghani A (2003) Medicinal plants of Bangladesh: chemical constituents and uses, 2nd edn. Asiatic Society of Bangladesh, Dhaka, pp 5–16

  45. Gopalan C, Sastri B, Rama V, Balasubramanian SC (1989) Nutritive value of Indian foods. ICMR. National Institute of Nutrition, Hyderabad, pp 110–125

  46. Graf E, Eaton JW (1990) Antioxidant functions of phytic acid. Free Radic Biol Med 8:61–69

  47. Gran B, Tabibzadeh N, Martin A, Ventura ES, Ware JH, Zhang GX, Parr JL, Kennedy AR, Rostami AM (2006) The protease inhibitor, Bowman–Birk Inhibitor, sup-pressesexperimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis. Mult Scler 12:688–697

  48. Granfeldt Y, Liljeberg H, Drews A, Newman R, Bjorck IM (1994) Glucose and insulin responses to barley products. Influence of food structure and amylose-amylopectin ratio. Am J Clin Nutr 59:1075–1082

  49. Gupta S, Abu-Ghannam N (2012) Probiotic fermentation of plant based products: possibilities and opportunities. Crit Rev Food Sci Nutr 52:183–199

  50. Gupta SK, Sharma PK, Ansari SH (2005) Antimicrobial activity of Dolichos biflorus seeds. Indian J Nat Prod 21:20–21

  51. Handa G, Singh J, Nandi LN, Sharma ML, Kaul A (1990) Pyroglutaminylgltamine- a new diurectic principle from Dolichos biflorus seeds. Indian J Chem, Sec B 29:1156–1158

  52. Harris RA, Joshi M, Jeoung NH, Obayashi M (2005) Overview of the molecular and biochemical basis of branched-chain amino acid catabolism. J Nutr 135(6):1527S–1530S

  53. Hasler CM (2000) The changing face of functional food. J Am Coll Nutr 19(5):499S–506S

  54. Hudson BJF, El-Difrawi EA (1979) The Sapogenins of the seeds of four lupinspecies. J Plant Food 3:181–186

  55. Jones JR, Lineback DM, Levine MJ (2006) Dietary reference intakes: implications for fiber labeling and consumption: a summary of the International Life Sciences Institute North American Fiber Workshop, June 1–2, 2004.Washington, DC. Nutr Rev 64:31–38

  56. Kawale SB, Kadam SS, Chavan UD, Chavan JK (2005) Effect of processing on insoluble dietary fiber and resistant starch in kidney bean and horse gram. J Food Sci Technol 42:361–362

  57. Kawsar SMA, Rahman MR, Huq E, Mosihuzzaman M, Nahar N, Mamun MIR (2003) Studies of different extractives of Macrotyloma uniflorum. Dhaka Univ J Pharm Sci 2:81–84

  58. Kawsar SMA, Huq E, Nahar N, Ozeki Y (2008) Identification and quantification of phenolic acids in Macrotyloma uniflorum by reversed phase-HPLC. Am J Plant Physiol 3(4):165–172

  59. Kawsar SMA, Mostafa G, Huq E, Nahar N, Ozeki Y (2009) Chemical constituents and hemolytic activity of Macrotyloma uniflorum L. Int J Biol Chem 3:42–48

  60. Kennedy A, Billings P, Maki A, Newberne P (1993) Effects of various preparations of dietary protease inhibitors on oral carcinogenesis in hamster induced by DMBA. Nutr Cancer 19:191–200

  61. Ko KM, Godin DV (1991) Effects of phytic acid on the myoglobin-t-butylhydroperoxide-catalysed oxidation of uric acid and peroxidation of erythrocyte membrane lipids. Mol Cell Biochem 101:23–29

  62. Koratkar R, Rao AV (1997) Effect of soybean saponins on azoxymethane-induced preneoplastic lesions in the colon of mice. Nutr Cancer 27:206–209

  63. Kumar V, Gowda LR (2013a) The contribution of two disulfide bonds in the trypsin binding domain of horsegram (Dolichos biflorus) Bowman-Birk inhibitor to thermal stability and functionality. Arch Biochem Biophys 537:49–61

  64. Kumar V, Gowda LR (2013b) Production of horsegram (Dolichos biflorus) Bowman-Birk inhibitor by an intein mediated protein purification system. Protein Express Purif 89:16–24

  65. Kumar P, Sreerama YN, Gowda LR (2002) Formation of Bowman – Birk inhibitors during the germination of horsegram (Dolichos biflorus). Phytochemistry 60:581–588

  66. Kumar P, Appu Rao AG, Hariharaputran S, Chandra N, Gowda LR (2004) Molecular mechanism of dimerisation of Bowman–Birk inhibitors, pivotal role of Asp76 in the dimerization. J Biol Chem 279:30425–30432

  67. Lairon D, Amiot MJ (1999) Flavonoids in food and natural antioxidants in wine. Curr Opin Lipidol 10:23–28

  68. Lajolo FM, Saura-Calixto F, Penna EW, Menezes EW (2001) Fibra dietética en Iberoamérica: tecnología y salud: obtención, caracterización, efecto fisiológico y aplicación en alimentos. Livraria Varela, São Paulo, 469

  69. Leterme P (2002) Recommendations by health organizations for pulse consumption. Brit J Nutr 88(Supplement 3):S239–S242

  70. Lori O, Thava V, James HH (2001) Phytic acid. Food Rev Int 17(4):419–431

  71. Losso JN (2008) The biochemical and functional food properties of the Bowman-Birk inhibitor. Crit Rev Food Sc Nutr 48:94–118

  72. Lule SU, Xia W (2005) Food phenolics, pros and coin: a review. Food Rev Int 21:367–388

  73. Maga JA (1978) Simple phenol and phenolic compounds in food flavor. Crit Rev Food Sci Nutr 10:323–372

  74. Malhotra SL (1982) Faecal urobilinogen levels and pH of stools in population groups with different incidence of cancer of the colon and their possible role in its etiology. J Roy Soc Med 75:709–714

  75. Marathe SA, Rajalakshmi V, Jamdar SN, Sharma A (2011) Comparative study on antioxidant activity of different varieties of commonly consumed legumes in India. Food Chem Toxicol 49:2005–2012

  76. Markievicz M, Kolanowka A, Gulewics K (1988) The chemical composition of debittered lupine seeds and their extract. Bull Pol Acad Sci Biol Sci 36:1–3

  77. McDougall GJ, Stewart D (2005) The inhibitory effects of berry polyphenols on digestive enzymes. Biofactors 23:189–195

  78. Mehra KL (2000) History of crop cultivation in pre-historic India. In: Choudhary SL, Sharma GS, Nene YL (eds) Ancient and medieval history of Indian agriculture and its relevance to sustainable agriculture in the 21st century. Rajasthan College of Agriculture, Udaipur, pp 11–16

  79. Messina MJ (1999) Legume and soybeans: overview of their nutritional profiles and health effects. Am J Clin Nutr 70(Suppl):439S–449S

  80. Morris JB (2008) Macrotyloma axillare and M. uniflorum; descriptor analysis, anthocyanin indexes and potential uses. Genet Resour Crop Ev 55:5–8

  81. Motsei ML, Lindsey KL, Van Staden J, Jaeger AK (2003) Screening of traditionally used South African plants for antifungal activity against Candida albicans. J Ethnopharmacol 86:235–241

  82. Muricken DG, Gowda LR (2010) Functional expression of horsegram (Dolichos biflorus) Bowman – Birk inhibitor and its self-association. Biochim Biophys Acta 1804:1413–1423

  83. Naik RG (2001) Effect of date of sowing on disease incidence and yields of horsegram (Macrotyloma uniflorum) Lamverdec. Legume Res 24(3):182–185

  84. Nakakuki T (2003) Development of functional oligosaccharides in Japan. Trends Glycosci Glyc 15:57–64

  85. Neelam DA (2007) Identification and quantification of nutraceuticals from bengal gram and horse gram seed coat. Dissertation for Bachelor of Technology. Department of Biotechnology, Sathyabama University Chennai (India), India

  86. Norazalina S, Norhaizan ME, Hairuszah I, Norashareena MS (2010) Anticarcinogenic efficacy of phytic acid extracted from rice bran on azoxymethane-induced colon carcinogenesis in rats. Exp Toxicol Pathol 62:259–268

  87. Oku T (1996) Oligosaccharides with beneficial health effects: a Japanese perspective. Nutr Rev 54:S59–S66

  88. Paśko P, Bartoń H, Zagrodzki P, Gorinstein S, Fołta M, Zachwieja Z (2009) Anthocyanins., total polyphenols and antioxidant activity in amaranth and quinoa seeds and sprouts during their growth. Food Chem 115:994–998

  89. Patwardhan B, Warude D, Pushpangadan P, Bhatt N (2005) Ayurveda and traditional Chinese medicine: a comparative overview. eCAM 2(4):465–473

  90. Perez RM (2003) Antiviral activity of compounds isolated from plants. Pharm Biol 41:107–157

  91. Perumal S, Sellamuthu M (2007) The antioxidant activity and free radical-scavenging capacity of dietary phenolic extracts from horse gram (Macrotyloma uniflorum (Lam.) Verdc.) seeds. Food Chem 105:950–958

  92. Phillips RD (1993) Starchy legumes in human nutrition, health and culture. Plant Food Hum Nutr 44:195–211

  93. Porres JM, Stahl CH, Cheng WH (1999) Dietary intrinsic phytate protects colon from lipid peroxidation in pigs with a moderately high dietary iron intake. Proc Soc Exp Biol Med 221:80–86

  94. Prosky L, DeVries JW (1991) Controlling dietary fiber in food products. In: Gottschalk W, Muller HP (eds) Proteins. Van Nostrand Reinhold, New York, pp 499–531

  95. Purseglove JW (1974) Dolichos uniflorus. In: Tropical Crops: Dicotyledons, Longman, London, pp 263–264

  96. Ramasarma PR, Rao DR (1991) Nature of the tryptic chymotryptic inhibitor from horse gram (Dolichos biflorus). Indian J Biochem Biophys 28:418–424

  97. Ramesh CK, Abdul R, Prabhakar BT, Vijay Avin BR, Aditya Rao SJ (2011) Antioxidant potentials in sprouts vs. seeds of Vigna radiata and Macrotyloma uniflorum. JAPS 01(07):99–103

  98. Ramulu P, Udayasekhararao P (1997) Effect of processing on dietary fiber content of cereals and pulses. Plant Food Hum Nutr 50:249–257

  99. Rao PS, Liu XK, Das DK, Weinstein GS, Tyras DH (1991) Protection of ischemic heart from reperfusion injury by myo-inositol hexaphosphate, a natural antioxidant. Ann Thorac Surg 52:908–912

  100. Raskin I, Ribnicky DM, Komarnytsky S, Ilic N, Poulev A, Borisjuk N, Brinker A, Moreno DA, Ripoll C, Yakoby N, O’Neal JM, Cornwell T, Pastor I, Fridlender B (2002) Plants and human health in the twenty first century. Trends Biotechnol 20:522–531

  101. Ravishankar K, Vishnu Priya PS (2012) In Vitro antioxidant activity of ethanolic seed extracts of macrotyloma uniflorum and cucumis melo for therapeutic potential. IJRPC 2(2):442–445

  102. Reddy BS (1999) Prevention of colon carcinogenesis by components of dietary fiber. Anticancer Res 19:3681–3683

  103. Reddy NRR, Pierson MD, Sathe SK (1984) Chemical, nutritional and physiological aspects of dry bean carbohydrates—a review. Food Chem 13:25–68

  104. Reddy PS, Ramanjulu S, Sudhakar C, Veeranjaneyulu K (1998) Differential sensitivity of stomatal and non-stomatal components of NaCl or Na2SO4 salinity in horsegram (Macrotyloma uniflorum (Lam.). Photosynthetica 35:99–105

  105. Reddy AM, Kumar SG, Jyothsnakumari G, Thimmanaik S, Sudhakar C (2005) Lead induced changes in antioxidant metabolism of horsegram (Macrotyloma uniflorum (Lam.) Verdc.) and bengalgram (Cicer arietinum L.). Chemosphere 60:97–104

  106. Reddy PCO, Sairanganayakulu G, Thippeswamy M, Sudhakar R, Reddy P, Sudhakar C (2008) Identification of stress-induced genes from the drought tolerant semi-arid legume crop horsegram (Macrotyloma uniflorum (Lam.) Verdc.) through analysis of subtracted expressed sequence tags. Plant Sci 175(3):372–384

  107. Redgwell RJ, Fischer M (2005) Dietary fiber as a versatile food component: an industrial perspective. Mol Nutr Food Res 49(6):521–535

  108. Richardson M (1991) The complete amino acid sequence of the major Kunitz trypsin inhibitor from the seeds of Prosopis juliflora. Phytochemistry 30:2829–2833

  109. Rickard SE, Thompson LU (1997) Interactions and biological effects of phytic acid. In: Shahidi F (ed) Antinutrients and phytochemicals in food. ACS symposium series No. 662. American Chemical Society, Washington, pp 294–312

  110. Russo S, Kema IP, Fokkema R, Boon JC, Willemse PHB, de Vries EGE, den Boer JA, Korf J (2003) Tryptophan as a link between psychopathology and somatic states. Psychosom Med 65(4):665–671

  111. Ryan CA (1981) Proteinase inhibitors. In: Marcus A (ed) The biochemistry of plants, vol 6. Academic, New York, pp 357–370

  112. Sandberg A-S (2002) Bioavailability of minerals in legumes. Brit J Nutr 88 (Suppl. 3): S281–S285

  113. Savithramma DL, Shambulingappa KG (1996) Genetic divergence studies in horse gram Macrotyloma uniflorum (L.) Verdec. Mysore J Agric Sci 30:223–229

  114. Scheppach W, Bartram HP, Richter F (1995) Role of short-chain fatty acids in the prevention of colorectal cancer. Eur J Cancer 31A:1077–1088

  115. Segev A, Badani H, Kapulnik Y, Shomer I, Oren-Shamir M, Galili S (2010) Determination of polyphenols, flavonoids, and antioxidant capacity in colored chickpea (Cicer arietinum L.). J Food Sci 75:S115–S119

  116. Severin S, Xia WS (2005) Milk biologically active components as nutraceuticals: review. Crit Rev Food Sci Nutr 45(7–8):645–656

  117. Seyler JE, Wildman REC, Layman DK (2007) Protein as a functional food ingredient for weight loss and maintaining body composition. In: Wildman REC (ed) Handbook of nutraceuticals and functional foods, 2nd edn. CRC Press, Boco Raton, pp 391–407

  118. Shamsuddin AM, Vucenik I, Cole KE (1997) IP6: a novel anticancer agent. Life Sci 61:343–354

  119. Sharma M, Kawatra A (1995) Effect of dietary fibre from cereal brans and legume seed coats on serum lipids in rats. Plant Food Hum Nutr 47:287–292

  120. Siddhuraju P, Becker K (2007) The antioxidant and free radical scavenging activities of processed cowpea (Vigna unguiculata (L.) Walp.) seed extracts. Food Chem 101:10–19

  121. Smartt J (1985) Evolution of grain legumes II. Old and new world pulses of lesser economic importance. Exp Agric 21:1–18

  122. Sodani SN, Paliwal RV, Jain LK (2004) Phenotypic stability for seed yield in rainfed Horsegram (Macrotyloma uniflorum [Lam.] Verdc). Paper presented in National Symposium on Arid Legumes for Sustainable Agriculture and Trade, 5–7 Nov., 2004. Central Arid Zone Research Institute, Jodhpur

  123. Soobrattee MA, Neergheen VS, Luximon-Ramma A, Aruomab OI, Bahorun T (2005) Phenolics as potential antioxidant therapeutic agents: mechanism and actions. Mutat Res 579:200–213

  124. Spiller GA (2001) Dietary fiber in prevention and treatment of disease. In: Spiller GA (ed) CRC handbook of dietary fiber in human nutrition. CRC Press LLC, Washington, pp 363–431

  125. Sreerama YN, Das JR, Rao DR, Gowda LR (1997) Double-headed trypsin/chymotrypsin inhibitors from horse gram (Dolichos biflorus): purification, molecular and kinetic properties. J Food Biochem 21:461–477

  126. Sreerama YN, Dennis A, Neelam, Vadakkoot BS, Vishwas MP (2010a) Distribution of nutrients and antinutrients in milled fractions of chickpea and horse gram: Seed coat phenolics and their distinct modes of enzyme inhibition. J Agric Food Chem 58(7):4322–4330

  127. Sreerama YN, Vadakkoot BS, Vishwas MP (2010b) Variability in the distribution of phenolic compounds in milled fractions of chickpea and horse gram: evaluation of their antioxidant properties. J Agric Food Chem 58:8322–8330

  128. Stanley DW, Aguilera JM (1985) A review of textural defects in cooked reconstituted legumes: the influence of structure and composition. J Food Biochem 9:277–323

  129. Sundaram U, Marimuthu M, Anupama V, Gurumoorthi P (2013) Comparative antioxidant quality evaluation of underutilized/less common south Indian legumes. Int J Pharm Bio Sci 4(2):117–126

  130. Taguri T, Tanaka T, Kouno I (2006) Antibacterial spectrum of plant polyphenols and extracts depending upon hydroxyphenyl structure. Biol Pharm Bull 29:2226–2235

  131. Tan SC (2000) Determinants of eating quality in fruits and vegetables. Proc Nutr Soc Aust 24:183–190

  132. Thirumaran AS, Kanchana S (2000) Role of pulses in human diets. In: Pulses production strategies in Tamil Nadu. Centre for Plant Breeding and Genetics, Tamil Nadu Agricultural University, Coimbatore, India, pp 129. http://www.tnau.ac.in/tech/pulsesbook.pdf. Accessed 13 July 2012

  133. Thompson LU (1993) Potential health benefits and problems associated with antinutrients in foods. Food Res Int 26:131–149

  134. Turner BL, Paphazy JM, Haygarth MP, Mckelvie DI (2002) Inositol phosphate in the environment. Online J R Soc 357:449–469

  135. Udensi EA, Ekwu FC, Isinguzo JN (2007) Antinutrient factors of vegetable cowpea (Sesquipedalis) seeds during thermal processing. PJN 6:194–197

  136. Urbano G, Lopez-Jurado M, Aranda P, Vidal-Valverde C, Tenorio E, Porres J (2000) The role of phytic acid in legumes: antinutrient or beneficial function. J Physiol Biochem 56:283–294

  137. Utsumi S (1992) Plant food protein engineering. Adv Food Nutr Res 36:89–208

  138. Whitehead RG, Young GP, Bhathal PS (1986) Effect of short chain fatty acids on new human colon carcinoma cell line (LIM 1215). Gut 27:1457–1463

  139. Witcombe JR, Billore M, Singhal HC, Patel NB, Tikka SBS, Saini DP, Sharma LK, Sharma R, Yadav SK, Yadavendra JP (2008) Improving the food security of low-resource farmers: introducing horsegram into maize-based cropping systems. Expl Agric 44:339–348

  140. Yadav S, Negi KS, Mandal S (2004) Protein and oil rich wild horsegram. Genet Resour Crop Ev 51:629–633

  141. Yadava ND, Vyas NL (1994) Arid legumes. Agrobios, India

  142. Zeven AC, de Wet JMJ (1982) Dictionary of cultivated plants and their regions of diversity. Centre for Agricultural Publication and Documentation, Wageningen

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Prasad, S.K., Singh, M.K. Horse gram- an underutilized nutraceutical pulse crop: a review. J Food Sci Technol 52, 2489–2499 (2015). https://doi.org/10.1007/s13197-014-1312-z

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Keywords

  • Antinutritional compounds
  • Prebiotic
  • Phytochemicals
  • Antioxidant
  • Bioactive compounds
  • Oligosaccharides