Abstract
Coexistence of carcinoma colon and tuberculosis is rare. The aim of this study is to present our 12-year experience on colonic carcinoma with coexisting colonic TB. Histopathology and imaging records of 189 patients of colonic carcinoma patients who underwent treatment in surgical unit 6 in our institute between January 2006 and December 2017 were reviewed. In 7 patients, histopathology and/or imaging studies were suggestive of coexistence of colonic carcinoma and tuberculosis. Fifteen cases of colonic tuberculosis were also reviewed. Descriptive statistics were used to summarize the data. Colonoscopic biopsy was suggestive of only malignant lesion in 6 cases and coexistence of TB and carcinoma in 1 case. The duration of symptoms spanned between 2 and 7 weeks. Anorexia and weight loss were the predominant symptoms. Colonoscopic biopsy was suggestive of only malignant lesion in 6 cases and coexistence of TB and carcinoma in 1 case. The morbidity was low and there was no surgery associated mortality. Clinical awareness and advancement in diagnostic studies and improvement in management strategies may guide and lead to early diagnosis, optimum therapeutic guidelines and thus improved outcome.
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References
Underwood MJ, Thompson MM, Sayers RD, Hall AW (1992) Presentation of abdominal tuberculosis to general surgeons. Br J Surg 79:1077–1079
Sinan T, Sheikh M, Ramadan S, Sahwney S, Behbehani A (2002) CT features in abdominal tuberculosis: 20 year experience. BMC Med Imaging 2:3
Chaudhary P
Khaniya S, Koirala R, Shakya VK, Adhikary S, Regmi R, Pandey SR, Agrawal CS (2009) Anorectal tuberculosis coexisting with adenocarcinoma: an unusual association. Cases J 2:143–145
Tanaka K, Kondo S, Hattori F, Yamashita Y, Matsuda M, Itoh K, Okada Y, Kojima K, Nakagami K, Suzuki H (1987) A case of colonic carcinoma associated with intestinal tuberculosis and an analysis of 26 cases reported in Japan. Gan-No-Rinsho. 33:1117–1123
Jain BK, Chandra SS, Narsimhan R, Ananthkrishnan N, Mehta RB (1991) Coexisting tuberculosis and carcinoma of the colon. Aust N Z J Surg 61:828–831
Chakravartty S, Chattopadhyay G, Ray D, Choudhury CR, Mandal S (2010) Concomitant tuberculosis and carcinoma colon: coincidence or causal nexus? Saudi J Gastroenterol 16:292–294
Kaplan MH, Armstrong D, Rosen P (1974) Tuberculosis complicating neoplastic disease: a review of 201 cases. Cancer. 33:850–858
Rao RN, Pandey R, Rana MK, Praveer R, Gupta A (2013) Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine needle aspiration cytology. J Cytol 30:130–135
Hulnick DH, Megibow AJ, Naidich DP, Hilton S, Cho KC, Balthazar EJ (1985) Abdominal tuberculosis: CT evaluation. Radiology. 157:199–204
Sharma S, Kumar A, Kumar V, Kakkar N, Gupta V (2016) Coexisting tuberculosis and adenocarcinoma of colon. Indian J Pathol Microbiol 59:560–561
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Study design, concept, drafting, data analysis: Poras Chaudhary. Data collection: Utsav Bhadana. Critical analysis: Poras Chaudhary and Romesh Lal.
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Chaudhary, P., Bhadana, U. & Lal, R. A Retrospective Cohort Study of Coexistence of Carcinoma and Tuberculosis of Colon: 12-Year Experience. Indian J Surg Oncol 12, 61–66 (2021). https://doi.org/10.1007/s13193-020-01249-6
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DOI: https://doi.org/10.1007/s13193-020-01249-6