Abstract
Hilar clamping is widely adopted in open partial nephrectomy, which is a treatment option for small renal cancer to reduce blood loss and improve surgical exposure, but whether to clamp either only artery or both artery and vein remains controversial. The purpose of this study is to determine whether artery only (AO) clamping is more beneficial than en bloc clamping by comparing perioperative variables in patients who underwent partial nephrectomy with either AO clamping or en bloc clamping. Eighty-eight patients with T1 renal tumor who underwent open partial nephrectomy with either AO or en bloc clamping between 2015 and 2018 at our institution were enrolled. They were randomly divided into two groups: AO group (n = 43) and artery and vein (AV) group (n = 45). Renal function was evaluated by serum creatinine (SCr) and differential renal function as determined by mercaptoacetyltriglycine renogram. AO clamping was associated with less total renal functional decrease until postoperative 7th day (P < 0.05). After postoperative 15th day, however, there was no significant difference in total renal functional impairment between AO and AV groups. There was also no significant difference in differential renal function change. Furthermore, AO clamping caused more blood loss and hemoglobin (Hb) decrease than en bloc clamping (P < 0.05). AO clamping is no more beneficial than en bloc clamping in partial nephrectomy, presenting with not significantly better long-term postoperative renal function than en bloc clamping.
Similar content being viewed by others
References
Laviana AA, Hu JC (2014) Current controversies and challenges in robotic-assisted, laparoscopic, and open partial nephrectomies. World J Urol 32(3):591–596
Thompson RH, Lane BR, Lohse CM, Leibovich BC, Fergany A, Frank I, Gill IS, Blute ML, Campbell SC (2010) Every minute counts when the renal hilum is clamped during partial nephrectomy. Eur Urol 58(3):340–345
Gong EM, Zorn KC, Orvieto MA, Lucioni A, Msezane LP, Shalhav AL (2008) Artery-only occlusion may provide superior renal preservation during laparoscopic partial nephrectomy. Urol 72(4):843–846
Berger A, Crouzet S, Canes D, Haber GP, Gill IS (2008) Minimally invasive nephron-sparing surgery. Curr Opin Urol 18(5):462–466
Volpe A, Panzarella T, Rendon RA, Haider MA, Kondylis FI, Jewett MA (2004) The natural history of incidentally detected small renal masses. Cancer 100(4):738–745
Scosyrev E, Messing EM, Sylvester R, Campbell S, van Poppel H (2014) Renal function after nephron-sparing surgery versus radical nephrectomy: results from EORTC randomized trial 30904. Eur Urol 65(2):372–377
Abuelo JG (2007) Normotensive ischemic acute renal failure. N Engl J Med 357(8):797–805
Secin FP (2008) Importance and limits of ischemia in renal partial surgery: experimental and clinical research. Adv Urol 2008:102461. https://doi.org/10.1155/2008/102461
Eckardt KU, Coresh J, Devuyst O, Johnson RJ, Köttgen A, Levey AS, Levin A (2013) Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 382(9887):158–169
Mir MC, Ercole C, Takagi T, Zhang Z, Velet L, Remer EM, Demirjian S, Campbell SC (2015) Decline in renal function after partial nephrectomy: etiology and prevention. J Urol 193(6):1889–1898
Neely WA, Turner MD (1959) The effect of arterial, venous, and arteriovenous occlusion on renal blood flow. Surg Gynecol Obstet 108(6):669–672
Acknowledgments
This research received no support from any other individuals or institutions.
Funding
In our country, the State provides all the citizens with free medical care and all the funds for scientific research are provided by the State.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of Interest
Kil-hun Song and Wol-song Jang declare that they have no conflict of interest.
Ethical Approval
All the procedures performed in our study were approved by the ethics committee of our institution and were in accordance with the 1964 Helsinki declaration and its later amendments.
Informed Consent
We obtained informed consents from all the patients who participated in our study.
Additional information
Publisher’s Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Song, Kh., Jang, Ws. Comparison of Hilar Clamping Techniques in Partial Nephrectomy: Is Artery Only Clamping Beneficial?. Indian J Surg Oncol 11, 325–328 (2020). https://doi.org/10.1007/s13193-020-01064-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13193-020-01064-z