Paraneoplastic Syndrome Associated with the Retroperitoneal Dedifferentiated Liposarcoma: an Atypical Presentation and Review of the Literature

  • Jeewan Ram VishnoiEmail author
  • Ankit Jain
  • Sanjeev Misra
  • Puneet Pareek
  • Meenakshi Rao
  • Binit Sureka
  • Ashok Puranik
Case Report


Retroperitoneal liposarcoma is usually asymptomatic until it is large enough to compress the surrounding organs. Here, we report a rare atypical case of primary retroperitoneal dedifferentiated liposarcoma who presented primarily with the misguiding and challenging paraneoplastic symptoms of high-grade fever and thrombocytosis instead of demonstrating the usual compressive symptoms. Such an extremely rare clinical presentation may mislead the diagnostic and treatment approach towards the search for medical causes, without a hint, that the tumor itself is causing these symptoms. Complete tumor excision usually leads to resolution of these paraneoplastic symptoms.


Paraneoplastic syndrome Dedifferentiated liposarcoma Retroperitoneum Fever Thrombocytosis 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.


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Copyright information

© Indian Association of Surgical Oncology 2019

Authors and Affiliations

  1. 1.Department of Surgical OncologyAll India Institute of Medical SciencesJodhpurIndia
  2. 2.Department of Surgical Oncology, Director & CEOAll India Institute of Medical SciencesJodhpurIndia
  3. 3.Department of RadiotherapyAll India Institute of Medical SciencesJodhpurIndia
  4. 4.Department of PathologyAll India Institute of Medical SciencesJodhpurIndia
  5. 5.Department of Diagnostic and Interventional RadiologyAll India Institute of Medical SciencesJodhpurIndia
  6. 6.Department of General SurgeryAll India Institute of Medical SciencesJodhpurIndia

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