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Recent Strategies and Paradigm Shift in Management of Hepatic Metastasis from Colorectal Cancer

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Abstract

The liver is the most common site for metastasis from colorectal cancers (CRCs). There are so many new armamentarium, which have increased the life expectancy and progression-free survival. There are various available guidelines, such as NCCN, ESMO, and ASCO, which provide an insight into the latest modalities and new protocols. We have tried to elucidate into paradigm shift of the management.

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References

  1. Misiakos EP, Karidis NP, Kouraklis G (2011) Current treatment for colorectal liver metastases. World J Gastroenterol 17(36):4067–4075

    Article  Google Scholar 

  2. Scheele J, Stangl R, Altendorf-Hofmann A (1990) Hepatic metastases from colorectal carcinoma: impact of surgical resection on the natural history. Br J Surg 77:1241–1246

    Article  CAS  Google Scholar 

  3. Clavien PA, Petrowsky H, DeOliveira ML et al (2007) Strategies for safer liver surgery and partial liver transplantation. N Engl J Med 356:1545–1155

    Article  Google Scholar 

  4. LiverMetSurvey: International registry of patients operated for colorectal liver metastasis. Available at: http://www.livermetsurvey.org

  5. Schmoll HJ, Van Cutsem E, Stein A et al (2012) ESMO Consensus Guidelines for management of patients with colon and rectal cancer: a personalized approach to clinical and decision making. Ann Oncol 23:2479–2516

    Article  CAS  Google Scholar 

  6. May BJ, Madoff DC (2012) Portal vein embolization: rationale, technique, and current application. Semin Interv Radiol 29(2):81–89

    Article  Google Scholar 

  7. Shoup M, Gonen M, D'Angelica M, Jamagin WR, DeMatteo RP, Schwartz LH et al (2003) Volumetric analysis predicts hepatic dysfunction in patients undergoing major liver resection. J Gastrointest Surg 7(3):325–330

    Article  Google Scholar 

  8. Viganò L, Capussotti L, Lapointe R, Barroso E, Hubert C, Giuliante F, Ijzermans JNM, Mirza DF, Elias D, Adam R (2014) Early recurrence after liver resection for colorectal metastases: risk factors, prognosis, and treatment. A LiverMetSurvey-based studyof 6,025 patients. Ann Surg Oncol 21:1276–1286

    Article  Google Scholar 

  9. Adam R (2003) Chemotherapy and surgery: new perspectives on the treatment of unresectable liver metastases. Ann Oncol 14(Suppl 2):13ii–1316ii

    Article  Google Scholar 

  10. Andres A, Toso C, Adam R, Barroso E, Hubert C, Capussotti L, Gerstel E, Roth A, Majno PE, Mentha G (2012) A survival analysis of the liver-first reversed management of advanced simultaneous colorectal liver metastases: a LiverMetSurvey-based study. Ann Surg 256:772–779

    Article  Google Scholar 

  11. Akgül Ö, Çetinkaya E, Ersöz Ş, Tez M (2014) Role of surgery in colorectal cancer liver metastases. World J Gastroenterol 20(20):6113–6122

    Article  Google Scholar 

  12. Salah S, Watanabe K, Welter S, Park JS, Park JW, Zabaleta J, Ardissone F, Kim J, Riquet M, Nojiri K, Gisabella M, Kim SY, Tanaka K, al-Haj Ali B (2012) Colorectal cancer pulmonary oligometastases: pooled analysis and construction of a clinical lung metastasectomy prognostic model. Ann Oncol 23:2649–2655

    Article  CAS  Google Scholar 

  13. Cassidy J, Clarke S, Dıaz-Rubio E et al (2008) Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol 26:2006–2012

    Article  CAS  Google Scholar 

  14. Somashekhar SP, Ashwin KR, Zaveri SS, Rauthan A, Patil P (2016) Assessment of tumor response and resection rates in unresectable colorectal liver metastases following neoadjuvant chemotherapy with cetuximab. Indian J Surg Oncol 7(1):11–17

    Article  CAS  Google Scholar 

  15. Pathak S, Jones R, Tang JM, Parmar C, Fenwick S, Malik H, Poston G (2011) Ablative ntherapies for colorectal liver metastases: a systematic review. Color Dis 13:252–265

    Article  Google Scholar 

  16. Jarnagin WR, Conlon K, Bodniewicz J, Dougherty E, DeMatteo RP, Blumgart LH et al (2001) A clinical scoring system predicts the yield of diagnostic laparoscopy in patients with potentially resectable hepatic colorectal metastases. Cancer 91:1121–1128

    Article  CAS  Google Scholar 

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Correspondence to Shekhar Gogna.

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Gogna, S., Goyal, P. Recent Strategies and Paradigm Shift in Management of Hepatic Metastasis from Colorectal Cancer. Indian J Surg Oncol 9, 456–460 (2018). https://doi.org/10.1007/s13193-018-0766-2

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  • DOI: https://doi.org/10.1007/s13193-018-0766-2

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