Skip to main content

Advertisement

SpringerLink
Log in

Interesting Presentation of Mycosis Fungoides in Staging on F-18 FDG PET/CT

  • Case Report
  • Published:
Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

Abstract

Mycosis fungoides is the major form of primary cutaneous T cell lymphoma. Its staging is based on the percentage of body surface involvement and biopsy-proven extra cutaneous nodal or visceral involvement. Literature shows F-18 FDG accumulation in disease-involved nodes and viscera with non-specific uptake due to co-existing inflammation limits its specificity. We report an interesting case of mycosis fungoides with bilateral upper limb edema and share its findings on F-18 FDG PET/CT.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

Data Availability

Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.

References

  1. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines); Primary Cutaneous Lymphoma, Version 2.2022- June 8 2022. https://www.nccn.org/professionals/physician_gls/pdf/primary_cutaneous.pdf. Accessed 16 Aug 2022.

  2. Olsen E, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, Knobler R, et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood. 2007;110:1713–22.

    Article  CAS  PubMed  Google Scholar 

  3. Willemze R, Jaffe ES, Burg G, Cerroni L, Berti E, Swerdlow SH, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105:3768–85.

    Article  CAS  PubMed  Google Scholar 

  4. Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow SH, et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood. 2019;133:1703–14.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Hristov AC, Tejasvi T, Wilcox RA. Mycosis fungoides and Sézary syndrome: 2019 update on diagnosis, risk-stratification, and management. Am J Hematol. 2019;94:1027–41.

    Article  PubMed  Google Scholar 

  6. D’Souza MM, D’Souza P, Sharma R, Jaimini A, Mondal A. Mycosis fungoides: positron emission tomography/computed tomography in staging and monitoring the effect of therapy. Indian J Nucl Med. 2015;30:165–7.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Proctor MS, Price NM, Cox AJ, Hoppe RT. Subcutaneous mycosis fungoides. Arch Dermatol. 1978;114:1326–8.

    Article  CAS  PubMed  Google Scholar 

  8. Tsai EY, Taur A, Espinosa L, Quon A, Johnson D, Dick S, et al. Staging accuracy in mycosis fungoides and sezary syndrome using integrated positron emission tomography and computed tomography. Arch Dermatol. 2006;142:577–84.

    Article  PubMed  Google Scholar 

  9. Sabet A, Ahmadzadehfar H, Schmid-Wendtner Hildegard M, Hinterthaner B, Biersack HJ, Ezziddin S. The impact of 18F-FDG-PET-CT findings in the management of a patient with mycosis fungoides. Int J Radiat Res. 2013;11:127–9.

    Google Scholar 

  10. Borella L, Lin M, Cains G, Watsom MA, Lin P. Utility of FDG-PET for staging in a case of mycosis fungoides. Dermatology. 2007;214:185–7.

    Article  PubMed  Google Scholar 

  11. Xu L, Pang H, Zhu J, Chen X, Guan L, Wang J, et al. Mycosis fungoides staged by 18F-flurodeoxyglucose positron emission tomography/computed tomography: case report and review of literature. Medicine. 2016;95:45 (e5044).

    Article  PubMed  Google Scholar 

  12. Feeney J, Horwitz S, Gönen M, Schöder H. Characterization of T-cell lymphomas by FDG PET/CT. Am J Roentgenol. 2010;195:333–40.

    Article  Google Scholar 

  13. Vaidya T, Badri T. Mycosis Fungoides. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2022 Available from: https://www.ncbi.nlm.nih.gov/books/NBK519572/. Accessed 16 Aug 2022.

Download references

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, All India Institute of Medical Sciences, Jodhpur, India

    Deepanksha Datta, Tanvi Sarwal & Rajesh Kumar

  2. Department of Medical Oncology, All India Institute of Medical Sciences, Jodhpur, India

    Sandeep Bairwa

  3. Department of Pathology & Lab Medicine, All India Institute of Medical Sciences, Jodhpur, India

    Vinay N. Gowda & Aasma Nalwa

Authors
  1. Deepanksha Datta
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tanvi Sarwal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rajesh Kumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sandeep Bairwa
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Vinay N. Gowda
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Aasma Nalwa
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

The study was designed by DD. PET/CT was performed and its images were prepared by TS, DD and RK. The pathology slides were studied and images were prepared by VG and AN. The first draft of the manuscript was prepared by TS and edited by DD, SB and RK. Treatment planning and chemotherapy was started and supervised by SB. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Rajesh Kumar.

Ethics declarations

Conflict of Interest

Deepanksha Datta, Tanvi Sarwal, Rajesh Kumar, Sandeep Bairwa, Vinay N Gowda and Aasma Nalwa declare that they have no competing interests.

Ethics Approval and Consent to Participate

The study was approved by the Institutional Ethics Committee of All India Institute of Medical Sciences, Jodhpur (Ref. No. AIIMS/IEC/2022/5363), and the requirement for written consent was waived by the Institutional Ethics Committee. All procedures performed in studies involving human participants were in accordance with the Helsinki declaration as revised in 2013 and its later amendments.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Datta, D., Sarwal, T., Kumar, R. et al. Interesting Presentation of Mycosis Fungoides in Staging on F-18 FDG PET/CT. Nucl Med Mol Imaging 57, 243–246 (2023). https://doi.org/10.1007/s13139-023-00794-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13139-023-00794-6

Keywords

Search

Navigation